The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Experimental Infection of Horses with West Nile virus
Open accessAbstract
A total of 12 horses of different breeds and ages were infected with West Nile virus (WNV) via the bites of infected Aedes albopictus mosquitoes. Half the horses were infected with a viral isolate from the brain of a horse (BC787), and half were infected with an isolate from crow brain (NY99-6625); both were NY99 isolates. Postinfection, uninfected female Ae. albopictus fed on eight of the infected horses. In the first trial, Nt antibody titers reached >1:320, 1:20, 1:160, and 1:80 for horses 1 to 4, respectively. In the second trial, the seven horses with subclinical infections developed Nt antibody titers >1:10 between days 7 and 11 post infection. The highest viremia level in horses fed upon by the recipient mosquitoes was approximately 460 Vero cell PFU/mL. All mosquitoes that fed upon viremic horses were negative for the virus. Horses infected with the NY99 strain of WNV develop low viremia levels of short duration; therefore, infected horses are unlikely to serve as important amplifying hosts for WNV in nature.
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Citations
Cites
Vector competence of North American mosquitoes (Diptera: Culicidae) for West Nile virus
Turell, M. J., O’Guinn, M. L., Dohm, D. J., & Jones, J. W. (2001) · Journal of Medical Entomology · doi:10.1603/0022-2585-38.2.130 · Cited by 633
Cited by
Epidemiology and Transmission Dynamics of West Nile Virus Disease
Hayes, E. B., Komar, N., Nasci, R. S., Montgomery, S. P., O'Leary, D. R., & Campbell, G. L. (2005) · Emerging Infectious Diseases · doi:10.3201/eid1108.050289a · Cited by 870
Self-citationWest Nile Virus: Epidemiology and Clinical Features of an Emerging Epidemic in the United States
Hayes, E. B., & Gubler, D. J. (2006) · Annual Review of Medicine · doi:10.1146/annurev.med.57.121304.131418 · Cited by 364
Verma, S., Lo, Y., Chapagain, M., Lum, S., Kumar, M., Gurjav, U., Luo, H., Nakatsuka, A., & Nerurkar, V. R. (2009) · Virology · doi:10.1016/j.virol.2008.11.047 · Cited by 254
MARRA, P. P., GRIFFING, S., CAFFREY, C., KILPATRICK, A. M., McLEAN, R., BRAND, C., SAITO, E., DUPUIS, A. P., KRAMER, L., & NOVAK, R. (2004) · BioScience · doi:10.1641/0006-3568(2004)054[0393:wnvaw]2.0.co;2 · Cited by 219
Metadata
- Authors
- Bunning, M. L., Bowen, R. A., Cropp, B. C., Sullivan, K. G., Davis, B. S., Komar, N., Godsey, M., Baker, D., Hettler, D. L., Holmes, D. A., Biggerstaff, B. J., & Mitchell, C. J.
- Venue
- Emerging Infectious Diseases
- Published
- 2002-04
- Volume
- 8
- Issue
- 4
- Pages
- 380-386
- ISSN
- 1080-6040 (ISSN-L)
- 1080-6059
- OpenAlex
- W2088899348
- Cited by
- 314
- References
- 1
- FWCI
- 19.33
- Type
- journal article
- Language
- en
- Open access
- diamond
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
