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Cited by 310

The DOI matches its Crossref record; 69 of the 69 references it cites were found in a registry or an index.

Cost Effectiveness of a Potential Vaccine for Human papillomavirus

Open access
Sanders, Gillian D., Taira, Al V.·2003·Emerging Infectious Diseases

Abstract

Human papillomavirus (HPV) infection, usually a sexually transmitted disease, is a risk factor for cervical cancer. Given the substantial disease and death associated with HPV and cervical cancer, development of a prophylactic HPV vaccine is a public health priority. We evaluated the cost-effectiveness of vaccinating adolescent girls for high-risk HPV infections relative to current practice. A vaccine with a 75% probability of immunity against high-risk HPV infection resulted in a life-expectancy gain of 2.8 days or 4.0 quality-adjusted life days at a cost of $246 relative to current practice (incremental cost effectiveness of $22,755/quality-adjusted life year [QALY]). If all 12-year-old girls currently living in the United States were vaccinated, >1,300 deaths from cervical cancer would be averted during their lifetimes. Vaccination of girls against high-risk HPV is relatively cost effective even when vaccine efficacy is low. If the vaccine efficacy rate is 35%, the cost effectiveness increases to $52,398/QALY. Although gains in life expectancy may be modest at the individual level, population benefits are substantial.

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Metadata

Authors
Sanders, G. D., & Taira, A. V.
Venue
Emerging Infectious Diseases
Published
2003-01
Volume
9
Issue
1
Pages
37-48
ISSN
  • 1080-6040 (ISSN-L)
  • 1080-6059
OpenAlex
W1969228545
Cited by
310
References
69
FWCI
12.56
Type
journal article
Language
en
Open access
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CoChat. (2026). Citation check: Cost Effectiveness of a Potential Vaccine for Human papillomavirus. https://app.cochat.ai/papers/10.3201/eid0901.020168
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Sanders, G. D., & Taira, A. V. (2003). Cost Effectiveness of a Potential Vaccine for Human papillomavirus. Emerging Infectious Diseases. https://doi.org/10.3201/eid0901.020168

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