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SARS Transmission, Risk Factors, and Prevention in Hong Kong
Open accessAbstract
We analyzed information obtained from 1,192 patients with probable severe acute respiratory syndrome (SARS) reported in Hong Kong. Among them, 26.6% were hospital workers, 16.1% were members of the same household as SARS patients and had probable secondary infections, 14.3% were Amoy Gardens residents, 4.9% were inpatients, and 9.9% were contacts of SARS patients who were not family members. The remaining 347 case-patients (29.1%) had undefined sources of infection. Excluding those <16 years of age, 330 patients with cases from "undefined" sources were used in a 1:2 matched case-control study. Multivariate analysis of this case-control study showed that having visited mainland China, hospitals, or the Amoy Gardens were risk factors (odds ratio [OR] 1.95 to 7.63). In addition, frequent mask use in public venues, frequent hand washing, and disinfecting the living quarters were significant protective factors (OR 0.36 to 0.58). In Hong Kong, therefore, community-acquired infection did not make up most transmissions, and public health measures have contributed substantially to the control of the SARS epidemic.
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Cited by
Physical interventions to interrupt or reduce the spread of respiratory viruses
Jefferson, T., Del Mar, C. B., Dooley, L., Ferroni, E., Al-Ansary, L. A., Bawazeer, G. A., van Driel, M. L., Nair, N. S., Jones, M. A., Thorning, S., et al. (2011) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006207.pub4 · Cited by 805
Effect of hand hygiene on infectious disease risk in the community setting: a meta-analysis
Aiello, A. E., Coulborn, R. M., Perez, V., & Larson, E. L. (2008) · American Journal of Public Health · doi:10.2105/ajph.2007.124610 · Cited by 796
Smith, R. D. (2006) · Social Science & Medicine · doi:10.1016/j.socscimed.2006.08.004 · Cited by 759
Nonpharmaceutical Interventions for Pandemic Influenza, National and Community Measures
World Health Organization Writing Group (2012) · Emerging Infectious Diseases · doi:10.3201/eid1201.051371 · Cited by 470
van der Sande, M., Teunis, P., & Sabel, R. (2008) · PLoS ONE · doi:10.1371/journal.pone.0002618 · Cited by 458
Metadata
- Authors
- Lau, J. T. F., Tsui, H., Lau, M., & Yang, X.
- Venue
- Emerging Infectious Diseases
- Published
- 2004-04
- Volume
- 10
- Issue
- 4
- Pages
- 587-592
- ISSN
- 1080-6040 (ISSN-L)
- 1080-6059
- OpenAlex
- W2060617977
- Cited by
- 338
- References
- 0
- FWCI
- 8.05
- Type
- journal article
- Language
- en
- Open access
- diamond
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