The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Norwalk Virus Shedding after Experimental Human Infection
Open accessAbstract
Noroviruses are the most common cause of viral gastroenteritis in the United States. To determine the magnitude and duration of virus shedding in feces, we evaluated persons who had been experimentally infected with Norwalk virus. Of 16 persons, clinical gastroenteritis (watery diarrhea and/or vomiting) developed in 11; symptomatic illness lasted 1-2 days. Virus shedding was first detected by reverse transcription-PCR (RT-PCR) 18 hours after participant inoculation and lasted a median of 28 days after inoculation (range 13-56 days). The median peak amount of virus shedding was 95 x 10(9) (range 0.5-1,640 x 10(9)) genomic copies/g feces as measured by quantitative RT-PCR. Virus shedding was first detected by antigen ELISA approximately 33 hours (median 42 hours) after inoculation and lasted 10 days (median 7 days) after inoculation. Understanding of the relevance of prolonged fecal norovirus excretion must await the development of sensitive methods to measure virus infectivity.
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Cites
Food-Related Illness and Death in the United States
Mead, P. S., Slutsker, L., Dietz, V., McCaig, L. F., Bresee, J. S., Shapiro, C., Griffin, P. M., & Tauxe, R. V. (1999) · Emerging Infectious Diseases · doi:10.3201/eid0505.990502 · Cited by 7,235
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Human susceptibility and resistance to Norwalk virus infection
Lindesmith, L., Moe, C., Marionneau, S., Ruvoen, N., Jiang, X., Lindblad, L., Stewart, P., LePendu, J., & Baric, R. (2003) · Nature Medicine · doi:10.1038/nm860 · Cited by 1,119
Natural History of Human Calicivirus Infection: A Prospective Cohort Study
Rockx, B., de Wit, M., Vennema, H., Vinjé, J., de Bruin, E., van Duynhoven, Y., & Koopmans, M. (2002) · Clinical Infectious Diseases · doi:10.1086/341408 · Cited by 512
Clinical Immunity in Acute Gastroenteritis Caused by Norwalk Agent
Parrino, T. A., Schreiber, D. S., Trier, J. S., Kapikian, A. Z., & Blacklow, N. R. (1977) · New England Journal of Medicine · doi:10.1056/nejm197707142970204 · Cited by 478
Norwalk Virus Infection of Volunteers: New Insights Based on Improved Assays
Graham, D. Y., Jiang, X., Tanaka, T., Opekun, A. R., Madore, H. P., & Estes, M. K. (1994) · Journal of Infectious Diseases · doi:10.1093/infdis/170.1.34 · Cited by 449
Self-citationDiagnosis of Noncultivatable Gastroenteritis Viruses, the Human Caliciviruses
Atmar, R. L., & Estes, M. K. (2001) · Clinical Microbiology Reviews · doi:10.1128/cmr.14.1.15-37.2001 · Cited by 375
Self-citationAmar, C. F. L., East, C. L., Gray, J., Iturriza-Gomara, M., Maclure, E. A., & McLauchlin, J. (2007) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-007-0290-8 · Cited by 318
The Epidemiologic and Clinical Importance of Norovirus Infection
Atmar, R. L., & Estes, M. K. (2006) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2006.03.001 · Cited by 311
Self-citationIn Vitro Cell Culture Infectivity Assay for Human Noroviruses
Straub, T. M., Höner zu Bentrup, K., Coghlan, P. O., Dohnalkova, A., Mayer, B. K., Bartholomew, R. A., Valdez, C. O., Bruckner-Lea, C. J., Gerba, C. P., Abbaszadegan, M. A., et al. (2007) · Emerging Infectious Diseases · doi:10.3201/eid1303.060549 · Cited by 304
Cited by
Replication of human noroviruses in stem cell–derived human enteroids
Ettayebi, K., Crawford, S. E., Murakami, K., Broughman, J. R., Karandikar, U., Tenge, V. R., Neill, F. H., Blutt, S. E., Zeng, X.-L., Qu, L., et al. (2016) · Science · doi:10.1126/science.aaf5211 · Cited by 1,305
Self-citationBuss, S. N., Leber, A., Chapin, K., Fey, P. D., Bankowski, M. J., Jones, M. K., Rogatcheva, M., Kanack, K. J., & Bourzac, K. M. (2015) · Journal of Clinical Microbiology · doi:10.1128/jcm.02674-14 · Cited by 554
Bányai, K., Estes, M. K., Martella, V., & Parashar, U. D. (2018) · The Lancet · doi:10.1016/s0140-6736(18)31128-0 · Cited by 445
Self-citationDesign, recruitment, and microbiological considerations in human challenge studies
Darton, T. C., Blohmke, C. J., Moorthy, V. S., Altmann, D. M., Hayden, F. G., Clutterbuck, E. A., Levine, M. M., Hill, A. V. S., & Pollard, A. J. (2015) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(15)00068-7 · Cited by 130
Foodborne and Food-Handler Norovirus Outbreaks: A Systematic Review
Hardstaff, J. L., Clough, H. E., Lutje, V., McIntyre, K. M., Harris, J. P., Garner, P., & O'Brien, S. J. (2018) · Foodborne Pathogens and Disease · doi:10.1089/fpd.2018.2452 · Cited by 114
Metadata
- Authors
- Atmar, R. L., Opekun, A. R., Gilger, M. A., Estes, M. K., Crawford, S. E., Neill, F. H., & Graham, D. Y.
- Venue
- Emerging Infectious Diseases
- Published
- 2008-10
- Volume
- 14
- Issue
- 10
- Pages
- 1553-1557
- ISSN
- 1080-6040 (ISSN-L)
- 1080-6059
- OpenAlex
- W2125283487
- Cited by
- 760
- References
- 19
- FWCI
- 23.07
- Type
- journal article
- Language
- en
- Open access
- diamond
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- Atmar, R. L., Opekun, A. R., Gilger, M. A., Estes, M. K., Crawford, S. E., Neill, F. H., & Graham, D. Y. (2008). Norwalk Virus Shedding after Experimental Human Infection. Emerging Infectious Diseases. https://doi.org/10.3201/eid1410.080117
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
