The DOI matches its Crossref record.
Evaluation of Commercially Available Anti–Dengue Virus Immunoglobulin M Tests
Open accessAbstract
Anti-dengue virus immunoglobulin M kits were evaluated.Test sensitivities were 21%-99% and specifi cities were 77%-98% compared with reference ELISAs.False-positive results were found for patients with malaria or past dengue infections.Three ELISAs showing strong agreement with reference ELISAs will be included in the World Health Organization Bulk Procurement Scheme.A n estimated 2.5-3 billion persons live in tropical and subtropical regions where dengue virus (DENV) is transmitted (1-3).Absence of inexpensive and accurate tests to diagnose dengue makes case management, surveillance, and outbreak investigation diffi cult.During infection, immunoglobulin (Ig) M against DENV can often be detected ≈5 days after onset of fever (4-6).First-time (primary) DENV infections typically have a stronger and more specifi c IgM response than subsequent (secondary) infections, for which the IgM response is low compared with a strong IgG response.These patterns underscore the need for evaluating the performance of commercially available tests, especially for diagnosis of secondary DENV infections (7-10). The StudyTo provide independent evaluation of dengue diagnostic tests, the United Nations International Children's Emergency Fund/United Nations Development Programme/World Bank/World Health Organization Special Programme for Research and Training in Tropical Diseases and the Pediatric Dengue Vaccine Initiative established a network of 7 laboratories based on criteria related to dengue expertise of the principal investigator, and type, capacity, management of the laboratory.The laboratories contributed serum specimens for the evaluation panel and conducted the evaluation.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Dengue: a continuing global threat
Guzman, M. G., Halstead, S. B., Artsob, H., Buchy, P., Farrar, J., Gubler, D. J., Hunsperger, E., Kroeger, A., Margolis, H. S., Martínez, E., et al. (2010) · Nature Reviews Microbiology · doi:10.1038/nrmicro2460 · Cited by 2,082
Self-citationVong, S., Khieu, V., Glass, O., Ly, S., Duong, V., Huy, R., Ngan, C., Wichmann, O., Letson, G. W., Margolis, H. S., et al. (2010) · PLoS Neglected Tropical Diseases · doi:10.1371/journal.pntd.0000903 · Cited by 118
Self-citation
Metadata
- Authors
- Hunsperger, E. A., Yoksan, S., Buchy, P., Nguyen, V. C., Sekaran, S. D., Enria, D. A., Pelegrino, J. L., Vázquez, S., Artsob, H., Drebot, M., Gubler, D. J., Halstead, S. B., Guzmán, M. G., Margolis, H. S., Nathanson, C.-M., Lic, N. R. R., Bessoff, K. E., Kliks, S., & Peeling, R. W.
- Venue
- Emerging Infectious Diseases
- Published
- 2009-03
- Volume
- 15
- Issue
- 3
- Pages
- 436-440
- ISSN
- 1080-6040 (ISSN-L)
- 1080-6059
- OpenAlex
- W2106667383
- Cited by
- 243
- References
- 0
- FWCI
- 17.60
- Type
- journal article
- Language
- en
- Open access
- diamond
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
