The DOI matches its OpenAlex record.
Oseltamivir-Resistant Influenza Virus A (H1N1), Europe, 2007–08 Season
Open accessAbstract
In Europe, the 2007-08 winter season was dominated by influenza virus A (H1N1) circulation through week 7, followed by influenza B virus from week 8 onward. Oseltamivir-resistant influenza viruses A (H1N1) (ORVs) with H275Y mutation in the neuraminidase emerged independently of drug use. By country, the proportion of ORVs ranged from 0% to 68%, with the highest proportion in Norway. The average weighted prevalence of ORVs across Europe increased gradually over time, from near 0 in week 40 of 2007 to 56% in week 19 of 2008 (mean 20%). Neuraminidase genes of ORVs possessing the H275Y substitution formed a homogeneous subgroup closely related to, but distinguishable from, those of oseltamivir-sensitive influenza viruses A (H1N1). Minor variants of ORVs emerged independently, indicating multiclonal ORVs. Overall, the clinical effect of ORVs in Europe, measured by influenza-like illness or acute respiratory infection, was unremarkable and consistent with normal seasonal activity.
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Cited by
Grohskopf, L. A., Sokolow, L. Z., Broder, K. R., Olsen, S. J., Karron, R. A., Jernigan, D. B., & Bresee, J. S. (2016) · MMWR. Recommendations and Reports · doi:10.15585/mmwr.rr6505a1 · Cited by 593
Favipiravir, an anti-influenza drug against life-threatening RNA virus infections
Shiraki, K., & Daikoku, T. (2020) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2020.107512 · Cited by 573
Influenza Virus Neuraminidase Structure and Functions
McAuley, J. L., Gilbertson, B. P., Trifkovic, S., Brown, L. E., & McKimm-Breschkin, J. L. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.00039 · Cited by 466
Hurt, A. C., Besselaar, T. G., Daniels, R. S., Ermetal, B., Fry, A., Gubareva, L., Huang, W., Lackenby, A., Lee, R. T. C., Lo, J., et al. (2016) · Antiviral Research · doi:10.1016/j.antiviral.2016.06.001 · Cited by 270
Self-citationTramontana, A. R., George, B., Hurt, A. C., Doyle, J. S., Langan, K., Reid, A. B., Harper, J. M., Thursky, K., Worth, L. J., Dwyer, D. E., et al. (2010) · Emerging Infectious Diseases · doi:10.3201/eid1607.091691 · Cited by 127
Metadata
- Authors
- Meijer, A., Lackenby, A., Hungnes, O., Lina, B., van der Werf, S., Schweiger, B., Opp, M., Paget, J., van de Kassteele, J., Hay, A. J., Zambon, M. C. F. A., & Scheme, O. B. O. T. E. I. S.
- Venue
- Emerging infectious diseases
- Publisher
- Centers for Disease Control and Prevention
- Published
- 2009-03-31
- Volume
- 15
- Issue
- 4
- Pages
- 552-560
- ISSN
- 1080-6040 (ISSN-L)
- OpenAlex
- W2135934555
- Cited by
- 362
- References
- 0
- FWCI
- 40.92
- Type
- journal article
- Language
- en
- Open access
- diamond
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- CoChat. (2026). Citation check: Oseltamivir-Resistant Influenza Virus A (H1N1), Europe, 2007–08 Season. https://app.cochat.ai/papers/10.3201/eid1504.081280
- The paper
- Meijer, A., Lackenby, A., Hungnes, O., Lina, B., van der Werf, S., Schweiger, B., Opp, M., Paget, J., van de Kassteele, J., Hay, A. J., Zambon, M. C. F. A., & Scheme, O. B. O. T. E. I. S. (2009). Oseltamivir-Resistant Influenza Virus A (H1N1), Europe, 2007–08 Season. Emerging infectious diseases. https://doi.org/10.3201/eid1504.081280
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
