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Prevention of Chronic Hepatitis B after 3 Decades of Escalating Vaccination Policy, China
Open accessAbstract
China's hepatitis B virus (HBV) prevention policy has been evaluated through nationally representative serologic surveys conducted in 1992 and 2006. We report results of a 2014 serologic survey and reanalysis of the 1992 and 2006 surveys in the context of program policy. The 2014 survey used a 2-stage sample strategy in which townships were selected from 160 longstanding, nationally representative, county-level disease surveillance points, and persons 1-29 years of age were invited to participate. The 2014 sample size was 31,713; the response rate was 83.3%. Compared with the 1992 pre-recombinant vaccine survey, HBV surface antigen prevalence declined 46% by 2006 and by 52% by 2014. Among children <5 years of age, the decline was 97%. China's HBV prevention program, targeted toward interrupting perinatal transmission, has been highly successful and increasingly effective. However, this progress must be sustained for decades to come, and elimination of HBV transmission will require augmented strategies.
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Cited by
Global burden of liver disease: 2023 update
Devarbhavi, H., Asrani, S. K., Arab, J. P., Nartey, Y. A., Pose, E., & Kamath, P. S. (2023) · Journal of Hepatology · doi:10.1016/j.jhep.2023.03.017 · Cited by 2,267
Pattyn, J., Hendrickx, G., Vorsters, A., & Van Damme, P. (2021) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiaa668 · Cited by 282
Metadata
- Authors
- Cui, F., Shen, L., Li, L., Wang, H., Wang, F., Bi, S., Liu, J., Zhang, G., Wang, F., Zheng, H., Sun, X., Miao, N., Yin, Z., Feng, Z., Liang, X., & Wang, Y.
- Venue
- Emerging Infectious Diseases
- Published
- 2017-05
- Volume
- 23
- Issue
- 5
- Pages
- 765-772
- ISSN
- 1080-6040 (ISSN-L)
- 1080-6059
- OpenAlex
- W2589531091
- Cited by
- 362
- References
- 0
- FWCI
- 21.15
- Type
- journal article
- Language
- en
- Open access
- diamond
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- CoChat. (2026). Citation check: Prevention of Chronic Hepatitis B after 3 Decades of Escalating Vaccination Policy, China. https://app.cochat.ai/papers/10.3201/eid2305.161477
- The paper
- Cui, F., Shen, L., Li, L., Wang, H., Wang, F., Bi, S., Liu, J., Zhang, G., Wang, F., Zheng, H., Sun, X., Miao, N., Yin, Z., Feng, Z., Liang, X., & Wang, Y. (2017). Prevention of Chronic Hepatitis B after 3 Decades of Escalating Vaccination Policy, China. Emerging Infectious Diseases. https://doi.org/10.3201/eid2305.161477
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
