Autochthonous Gnathostomiasis in Madagascar
Open accessAbstract
We used molecular tools to identify an autochthonous case of gnathostomiasis in Madagascar. This severe ocular infection, caused by Gnathostoma spinigerum nematodes, led to vision loss in the patient's left eye. Clinicians should be aware of this parasitosis in Madagascar and other countries in Africa.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In a recent report from Madagascar, mebendazole (200 mg daily for 21 days) was prescribed after surgical extraction of a G. spinigerum larva from an eye to treat probable further infection and cure intestinal nematode infections.
“in a recent report from Madagascar, a G. spinigerum 3rd-stage larva was surgically extracted from an eye of a woman, and then mebendazole (200 mg daily for 21 days) was prescribed to treat probable further infection by Gnathostoma parasites and also to cure a wide spectrum of intestinal nematode infections [142]”
From Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update (2021) · cites this paper as [142]
The Study reports removal of a third-stage G. spinigerum larva from the woman’s eye, followed by mebendazole at 100 mg twice daily for 21 days to treat probable further Gnathostoma infection. The Conclusions say mebendazole was prescribed under a local protocol used to cure a wide spectrum of nematode infections, but do not specify intestinal infections. The claimed daily total of 200 mg is correct. (LLM, conf=0.87)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
No references could be resolved yet.
Research works printed but not linked: 14
- [1]Bravo F, Gontijo B. Gnathostomiasis: an emerging infectious disease relevant to all dermatologists. An Bras Dermatol. 2018; 93: 172– 80. 10.1590/abd1806-4841.20187498 29723377 PMC5916386 · DOI
- [2]Jongthawin J, Intapan PM, Sanpool O, Sadaow L, Janwan P, Thanchomnang T, et al. Three human gnathostomiasis cases in Thailand with molecular identification of causative parasite species. Am J Trop Med Hyg. 2015; 93: 615– 8. 10.4269/ajtmh.15-0284 26055743 PMC4559707 · DOI
- [3]Herman JS, Chiodini PL. Gnathostomiasis, another emerging imported disease. Clin Microbiol Rev. 2009; 22: 484– 92. 10.1128/CMR.00003-09 19597010 PMC2708391 · DOI · Paper page
- [4]Katchanov J, Sawanyawisuth K, Chotmongkoi V, Nawa Y. Neurognathostomiasis, a neglected parasitosis of the central nervous system. Emerg Infect Dis. 2011; 17: 1174– 80. 10.3201/eid1707.101433 21762569 PMC3321562 · DOI
- [5]Nawa Y, Katchanov J, Yoshikawa M, Rojekittikhun W, Dekumyoy P, Kusolusuk T, et al. Ocular gnathostomiasis: a comprehensive review. The Journal of Tropical Medicine and Parasitology. 2010; 33: 77– 86.
- [6]Herman JS, Wall EC, van-Tulleken C, Godfrey-Faussett P, Bailey RL, Chiodini PL. Gnathostomiasis acquired by British tourists in Botswana. Emerg Infect Dis. 2009; 15: 594– 7. 10.3201/1504.081646 19331741 PMC2671435 · DOI
- [7]Boonroumkaew P, Sanpool O, Rodpai R, Sadaow L, Somboonpatarakun C, Laymanivong S, et al. Molecular identification and genetic diversity of Gnathostoma spinigerum larvae in freshwater fishes in southern Lao PDR, Cambodia, and Myanmar. Parasitol Res. 2019; 118: 1465– 72. 10.1007/s00436-019-06292-z 30911911 · DOI
- [8]Tamura K, Peterson D, Peterson N, Stecher G, Nei M, Kumar S. MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol Biol Evol. 2011; 28: 2731– 9. 10.1093/molbev/msr121 21546353 PMC3203626 · DOI
- [9]Jeremiah CJ, Harangozo CS, Fuller AJ. Gnathostomiasis in remote northern Western Australia: the first confirmed cases acquired in Australia. Med J Aust. 2011; 195: 42– 4. 10.5694/j.1326-5377.2011.tb03188.x 21728942 · DOI
- [10]Hale DC, Blumberg L, Frean J. Case report: gnathostomiasis in two travelers to Zambia. Am J Trop Med Hyg. 2003; 68: 707– 9. 10.4269/ajtmh.2003.68.707 12887031 · DOI
- [11]Müller-Stöver I, Richter J, Häussinger D. [Infection with Gnathostoma spinigerum as a cause of eosinophilic oesophagitis]. Dtsch Med Wochenschr. 2004; 129: 1973– 5. 15375739
- [12]Frean J. Gnathostomiasis acquired by visitors to the Okavango Delta, Botswana. Trop Med Infect Dis. 2020; 5: 39. 10.3390/tropicalmed5010039 32155896 PMC7157749 · DOI
- [13]Moore DA, McCroddan J, Dekumyoy P, Chiodini PL. Gnathostomiasis: an emerging imported disease. Emerg Infect Dis. 2003; 9: 647– 50. 10.3201/eid0906.020625 12781003 PMC3000140 · DOI
- [14]Veraldi S, Carrera C, Pravettoni C, Alessi E. A case of suspected cutaneous gnathostomiasis. G Ital Dermatol Venereol. 2000; 135: 363– 5.
Cited by
Sorted by citations
Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update
Chai, J.-Y., Jung, B.-K., & Hong, S.-J. (2021) · The Korean Journal of Parasitology · doi:10.3347/kjp.2021.59.3.189 · Cited by 286 · see citing works
- Authors
- Raharisoa, A., Izri, A., Andrianjafy, R. L., Rajaona, R. A., Marteau, A., Durand, R., & Akhoundi, M.
- Affiliations
- Université Paris-Saclay (FR)
- Corresponding author
- Akhoundi, Mohammad
- Venue
- Emerging Infectious Diseases
- Published
- 2020-08
- Volume
- 26
- Issue
- 8
- Pages
- 1875-1877
- ISSN
- 1080-6040 (ISSN-L)
- 1080-6059
- PMC
- PMC7392461
- OpenAlex
- W3042552889
- Cited by
- 7
- References
- 0
- Citations by year
- 2026: 1 · 2024: 1 · 2022: 2 · 2021: 3
- FWCI
- 0.88
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- cc-by
- Locations
- Emerging infectious diseases (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Insect Science › Mollusks and Parasites Studies
- Health Sciences › Medicine › Pathology and Forensic Medicine › Parasitic infections in humans and animals
- Life Sciences › Immunology and Microbiology › Parasitology › Parasites and Host Interactions
- Keywords
- gnathostomiasis, Gnathostoma spinigerum, autochthonous infection, ocular infection, vision loss, Madagascar, Africa
- MeSH terms
- Africa, Animals, Gnathostoma, Humans, Madagascar, Gnathostomiasis
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
