Cited by 30Medicinal Plants and NeuroprotectionAlzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Alzheimer’s Disease and Herbal Combination Therapy: A Comprehensive Review

Open access
Pradeep, Sushma, Jain, Anisha S., Dharmashekara, Chandan, Prasad, Shashanka K., Kollur, Shiva Prasad, Syed, Asad, Shivamallu, Chandan·2020·Journal of Alzheimer s Disease Reports

Abstract

Alzheimer's disease (AD) was first described in 1907 and got its name after Alois Alzheimer, a German psychiatrist and neuropathologist. This disease starts slow, increasing gradually to worsen in the due course of time. AD is mainly characterized by the associated dementia, which is a decline of cognitive effects such as memory, praxis, and orientation. The dementia is further highlighted by the presence of psychological and behavioral symptoms. Additionally, AD is also associated with the multiple interconnected pathways linked neuropathological changes such as the formation of neurofibrillary tangles and amyloid-β plaques inside the brain. AD therapeutics have been of prime concern over the decades, resulting in the elucidation of promising therapeutic targets. The requirement of AD stage dependent optimized conditions has necessitated a combinatorial approach toward treatment. The priority in AD research has remained to develop disease-modifying and development-reducing drugs for treatment regimens followed during the early and later stages, respectively.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.3233/adr-200228

Cites

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

The citation lists haven’t been fetched yet

References 58 · Cited by 30

Authors
Pradeep, S., Jain, A. S., Dharmashekara, C., Prasad, S. K., Kollur, S. P., Syed, A., & Shivamallu, C.
Affiliations
  • JSS Academy of Higher Education and Research (IN)
  • Amrita Vishwa Vidyapeetham (IN)
  • King Saud University (SA)
Corresponding author
  • Kollur, Shiva Prasad
  • Shivamallu, Chandan
Venue
Journal of Alzheimer s Disease Reports
Published
2020-10-08
Volume
4
Issue
1
Pages
417-429
ISSN
2542-4823 (ISSN-L)
OpenAlex
W3092202660
Cited by
30
References
58
Citations by year
2026: 6 · 2025: 4 · 2024: 7 · 2023: 6 · 2022: 6 · 2021: 1
FWCI
0.66
Type
journal article
Language
en
Open access
Locations
  • Journal of Alzheimer s Disease Reports (publishedVersion, cc-by-nc)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics
  • Health Sciences › Medicine › Complementary and alternative medicine › Medicinal Plants and Neuroprotection
  • Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Keywords
Alzheimer's disease, herbal combination therapy, dementia, amyloid plaques, neurofibrillary tangles, disease-modifying drugs, symptomatic treatment, cognitive decline

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review