Disrupted White Matter Integrity and Cognitive Functions in Amyloid-β Positive Alzheimer’s Disease with Concomitant Lobar Cerebral Microbleeds

Qiao, Yanan; Sun, Yu; Guo, Jing; Chen, Yaojing; Hou, Wenjie; Zhang, Junying; Peng, Dantao

doi:10.3233/jad-215251

Disrupted White Matter Integrity and Cognitive Functions in Amyloid-β Positive Alzheimer’s Disease with Concomitant Lobar Cerebral Microbleeds

Background Lobar cerebral microbleeds (CMBs), which can impair white matter (WM), are often concomitant with definite Alzheimer's disease (AD). Objective To explore the features of cognitive impairments and WM disruptions due to lobar CMBs in patients with AD. Methods There were 310 participants …