The DOI matches its Crossref record; 170 of the 172 references it cites were found in a registry or an index.
Bilateral vestibulopathy: Diagnostic criteria Consensus document of the Classification Committee of the Bárány Society1
Open accessAbstract
This paper describes the diagnostic criteria for bilateral vestibulopathy (BVP) by the Classification Committee of the Bárány Society. The diagnosis of BVP is based on the patient history, bedside examination and laboratory evaluation. Bilateral vestibulopathy is a chronic vestibular syndrome which is characterized by unsteadiness when walking or standing, which worsen in darkness and/or on uneven ground, or during head motion. Additionally, patients may describe head or body movement-induced blurred vision or oscillopsia. There are typically no symptoms while sitting or lying down under static conditions.The diagnosis of BVP requires bilaterally significantly impaired or absent function of the vestibulo-ocular reflex (VOR). This can be diagnosed for the high frequency range of the angular VOR by the head impulse test (HIT), the video-HIT (vHIT) and the scleral coil technique and for the low frequency range by caloric testing. The moderate range can be examined by the sinusoidal or step profile rotational chair test.For the diagnosis of BVP, the horizontal angular VOR gain on both sides should be <0.6 (angular velocity 150-300°/s) and/or the sum of the maximal peak velocities of the slow phase caloric-induced nystagmus for stimulation with warm and cold water on each side <6°/s and/or the horizontal angular VOR gain <0.1 upon sinusoidal stimulation on a rotatory chair (0.1 Hz, Vmax = 50°/sec) and/or a phase lead >68 degrees (time constant of <5 seconds). For the diagnosis of probable BVP the above mentioned symptoms and a bilaterally pathological bedside HIT are required.Complementary tests that may be used but are currently not included in the definition are: a) dynamic visual acuity (a decrease of ≥0.2 logMAR is considered pathological); b) Romberg (indicating a sensory deficit of the vestibular or somatosensory system and therefore not specific); and c) abnormal cervical and ocular vestibular-evoked myogenic potentials for otolith function.At present the scientific basis for further subdivisions into subtypes of BVP is not sufficient to put forward reliable or clinically meaningful definitions. Depending on the affected anatomical structure and frequency range, different subtypes may be better identified in the future: impaired canal function in the low- or high-frequency VOR range only and/or impaired otolith function only; the latter is evidently very rare.Bilateral vestibulopathy is a clinical syndrome and, if known, the etiology (e.g., due to ototoxicity, bilateral Menière's disease, bilateral vestibular schwannoma) should be added to the diagnosis. Synonyms include bilateral vestibular failure, deficiency, areflexia, hypofunction and loss.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“For example, PPPD does not cause oscillopsia, but oscillopsia is present in only 30–40% of patients with bilateral vestibulopathy.”
In the citing paper
“Bilateral vestibulopathy is best distinguished from PPPD by its characteristic findings on physical examination and laboratory testing [45], such as bilaterally positive head thrusts and diminished responses on head impulse testing, caloric irrigation, or sinusoidal stimulation in a rotary chair.”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Lower-extremity function in persons over the age of 70 years as a predictor of subsequent disability
Guralnik, J. M., Ferrucci, L., Simonsick, E. M., Salive, M. E., & Wallace, R. B. (1995) · New England Journal of Medicine · doi:10.1056/nejm199503023320902 · Cited by 4,083
The Development of the Dizziness Handicap Inventory
Jacobson, G. P., & Newman, C. W. (1990) · Archives of Otolaryngology - Head and Neck Surgery · doi:10.1001/archotol.1990.01870040046011 · Cited by 2,412
Falls Efficacy as a Measure of Fear of Falling
Tinetti, M. E., Richman, D., & Powell, L. H. (1990) · Journal of Gerontology · doi:10.1093/geronj/45.6.p239 · Cited by 2,113
Hearing Loss and Incident Dementia
Lin, F. R., Metter, E. J., O’Brien, R., Resnick, S. M., Zonderman, A. B., & Ferrucci, L. (2011) · Archives of Neurology · doi:10.1001/archneurol.2010.362 · Cited by 1,633
Baltes, P. B., & Lindenberger, U. (1997) · Psychology and Aging · doi:10.1037/0882-7974.12.1.12 · Cited by 1,509
Lopez-Escamez (2015) · doi:10.3233/ves-150549 · Cited by 1,486
A Clinical Sign of Canal Paresis
Halmagyi, G. M., & Curthoys, I. S. (1988) · Archives of Neurology · doi:10.1001/archneur.1988.00520310043015 · Cited by 1,286 · cited 3×
“the tip of the examiner’s nose, which indicates a deficient VOR [27].”
BackgroundInfluentialEpidemiology of benign paroxysmal positional vertigo: a population based study
von Brevern, M., Radtke, A., Lezius, F., Feldmann, M., Ziese, T., Lempert, T., & Neuhauser, H. K. (2006) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.2006.100420 · Cited by 1,262
Vestibular migraine: Diagnostic criteria
Lempert, T., Olesen, J., Furman, J., Waterston, J., Seemungal, B., Carey, J., Bisdorff, A., Versino, M., Evers, S., & Newman-Toker, D. (2012) · Journal of Vestibular Research · doi:10.3233/ves-2012-0453 · Cited by 1,109
Disorders of Balance and Vestibular Function in US Adults
Agrawal, Y., Carey, J. P., Santina, C. C. D., Schubert, M. C., & Minor, L. B. (2009) · Archives of Internal Medicine · doi:10.1001/archinternmed.2009.66 · Cited by 1,025
Research works printed but not linked: 4
- von, 2015, Benign paroxysmal positional vertigo: Diagnostic criteria, J Vestib Res, 25, 105
- Goulson, 2014, Balance Function Assessment and Management
- Agrawal, 2013, Semicircular canal, saccular and utricular function in patients with bilateral vestibulopathy: Analysis based on etiology, J Neurol, 260, 876, 10.1007/s00415-012-6724-y · DOI
- Kirchner, 2011, Clinical, electrophysiological, and MRI findings in patients with cerebellar ataxia and a bilaterally pathological head-impulse test, Ann N Y Acad Sci, 1233, 127, 10.1111/j.1749-6632.2011.06175.x · DOI
Cited by
Sorted by citations
Staab, J. P., Eckhardt-Henn, A., Horii, A., Jacob, R., Strupp, M., Brandt, T., & Bronstein, A. (2017) · Journal of Vestibular Research · doi:10.3233/ves-170622 · Cited by 840
“lopathy is best distinguished from PPPD by its characteristic findings on physical examination and laboratory testing [45], such as bilaterally positive head thrusts and diminished responses on head impulse testing, caloric irrigation, or sinusoidal stimulation in a rotary chair.”
BackgroundSelf-citationVestibular evoked myogenic potentials in practice: Methods, pitfalls and clinical applications
Rosengren, S. M., Colebatch, J. G., Young, A. S., Govender, S., & Welgampola, M. S. (2019) · Clinical Neurophysiology Practice · doi:10.1016/j.cnp.2019.01.005 · Cited by 302
“Since the diagnosis of definite BVP requires impairment of horizontal canal function (Strupp et al., 2017), the prevalence of abnormalities on caloric tests and vHIT is likely to be inflated in subjects diagnosed with BVP comparison to VEMP”
BackgroundAcute unilateral vestibulopathy/vestibular neuritis: Diagnostic criteria
Strupp, M. L., Bisdorff, A., FURMAN, J. M. R., Hornibrook, J., Jahn, K., Maire, R., Newman‐Toker, D. E., & Magnusson, M. (2022) · Journal of Vestibular Research · doi:10.3233/ves-220201 · Cited by 272
Cerebellar ataxia, neuropathy, vestibular areflexia syndrome due to RFC1 repeat expansion
Cortese, A., Tozza, S., Yau, W. Y., Rossi, S., Beecroft, S. J., Jaunmuktane, Z., Dyer, Z., Ravenscroft, G., Lamont, P. J., Mossman, S., et al. (2020) · Brain · doi:10.1093/brain/awz418 · Cited by 227
Agrawal, Y., van de Berg, R., Wuyts, F. L., Walther, L. E., Magnusson, M., Oh, E. S., Sharpe, M., & Strupp, M. L. (2019) · Journal of Vestibular Research · doi:10.3233/ves-190672 · Cited by 209
Metadata
- Authors
- Strupp, M., Kim, J.-S., Murofushi, T., Straumann, D., Jen, J. C., Rosengren, S. M., Della Santina, C. C., & Kingma, H.
- Affiliations
- LMU Klinikum (DE)
- Seoul National University (KR)
- Teikyo University Hospital, Mizonokuchi (JP)
- University of Zurich (CH)
- University of California, Los Angeles (US)
- The University of Sydney (AU)
- Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Baltimore, USA
- National Research Tomsk State University (RU)
- Corresponding author
- Strupp, Michael
- ORCID
- Venue
- Journal of Vestibular Research
- Publisher
- SAGE Publications
- Published
- 2017-10-21
- Volume
- 27
- Issue
- 4
- Pages
- 177-189
- ISSN
- 0957-4271 (ISSN-L)
- 1878-6464
- PMC
- PMC9249284
- OpenAlex
- W2758384006
- Cited by
- 592
- References
- 172
- Citations by year
- 2026: 55 · 2025: 92 · 2024: 67 · 2023: 83 · 2022: 66 · 2021: 82 · 2020: 73 · 2019: 42 · 2018: 28 · 2017: 4
- FWCI
- 19.94
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Vestibular Research (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Zurich Open Repository and Archive (University of Zurich) (acceptedVersion, cc-by-nc)
- Research Publications (Maastricht University) (submittedVersion, cc-by-nc)
- Zurich Open Repository and Archive (University of Zurich) (submittedVersion, cc-by-nc)
- Research Publications (Maastricht University) (submittedVersion, other-oa)
- Zurich Open Repository and Archive (University of Zurich)
- Funders
- Bundesministerium für Bildung und Forschung (01EO0901, 01EO1401)
- Russian Science Foundation (17-15-01249)
- Deutschen Schwindel- und Gleichgewichtszentrum
- Topics
- Life Sciences › Neuroscience › Neurology › Vestibular and auditory disorders
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Syncope and Autonomic Disorders
- Health Sciences › Medicine › Surgery › Nausea and vomiting management
- Keywords
- bilateral vestibulopathy, diagnostic criteria, vestibulo-ocular reflex, head impulse test, video head impulse test, caloric test, oscillopsia, vestibular function testing, otolith function, dynamic visual acuity, Romberg test, vestibular evoked myogenic potentials
- MeSH terms
- Point-of-Care Testing, Bilateral Vestibulopathy, Caloric Tests, Diagnosis, Differential, Head, Humans, Functional Laterality, Motion, Movement Disorders, Nystagmus, Pathologic, Reflex, Vestibulo-Ocular, Rotation, Sclera, Vestibular Function Tests, Vision Disorders, Vestibular Evoked Myogenic Potentials, Head Impulse Test
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
