Non-bulky Lesions in Human DNA: The Ways of Formation, Repair, and Replication

Kinetic Mechanism for the Flipping and Excision of 1,N6-Ethenoadenine by Human Alkyladenine DNA Glycosylase

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Tyrosyl-DNA phosphodiesterase 1 initiates repair of apurinic/apyrimidinic sites

Lebedeva, N. A., Rechkunova, N. I., El‐Khamisy, S. F., & Lavrik, O. I. (2012) · Biochimie · doi:10.1016/j.biochi.2012.04.004 · Cited by 48

Handling the 3-methylcytosine lesion by six human DNA polymerases members of the B-, X- and Y-families

Furrer, A., & van Loon, B. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt889 · Cited by 48

Loss of Neil3, the major DNA glycosylase activity for removal of hydantoins in single stranded DNA, reduces cellular proliferation and sensitizes cells to genotoxic stress

Rolseth, V., Krokeide, S. Z., Kunke, D., Neurauter, C. G., Suganthan, R., Sejersted, Y., Hildrestrand, G. A., Bjørås, M., & Luna, L. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2012.12.024 · Cited by 45

Genetic and Biochemical Characterization of Human AP Endonuclease 1 Mutants Deficient in Nucleotide Incision Repair Activity

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Next-generation sequencing reveals the biological significance of the N 2,3-ethenoguanine lesion in vivo

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O6-Methylguanine-induced replication blocks

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Miscoding Properties of 3,N4-Etheno-2‘-deoxycytidine in Reactions Catalyzed by Mammalian DNA Polymerases

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DNA Synthesis across an Abasic Lesion by Human DNA Polymerase ι

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Identification of 5-formyluracil DNA glycosylase activity of human hNTH1 protein

Miyabe, I. (2002) · Nucleic Acids Research · doi:10.1093/nar/gkf460 · Cited by 38

Mutagenic Properties of 3-(Deoxyguanosin-N2-yl)-2-acetylaminofluorene, a Persistent Acetylaminofluorene-Derived DNA Adduct in Mammalian Cells

Yasui, M., Dong, H., Bonala, R., Suzuki, N., Ohmori, H., Hanaoka, F., Johnson, F., Grollman, A. P., & Shibutani, S. (2004) · Biochemistry · doi:10.1021/bi048279+ · Cited by 38

Basis of Miscoding of the DNA Adduct N2,3-Ethenoguanine by Human Y-family DNA Polymerases

Zhao, L., Pence, M. G., Christov, P. P., Wawrzak, Z., Choi, J.-Y., Rizzo, C. J., Egli, M., & Guengerich, F. P. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.403253 · Cited by 36

Quantitative analysis of the efficiency and mutagenic spectra of abasic lesion bypass catalyzed by human Y-family DNA polymerases

Sherrer, S. M., Fiala, K. A., Fowler, J. D., Newmister, S. A., Pryor, J. M., & Suo, Z. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq719 · Cited by 36

Human DNA polymerase κ forms nonproductive complexes with matched primer termini but not with mismatched primer termini

Carlson, K. D., Johnson, R. E., Prakash, L., Prakash, S., & Washington, M. T. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0605785103 · Cited by 35

Highly Mutagenic Exocyclic DNA Adducts Are Substrates for the Human Nucleotide Incision Repair Pathway

Prorok, P., Saint‐Pierre, C., Gasparutto, D., Fedorova, O. S., Ishchenko, A. A., Leh, H., Buckle, M., Tudek, B., & Saparbaev, M. K. (2012) · PLoS ONE · doi:10.1371/journal.pone.0051776 · Cited by 34

Generation and repair of AID-initiated DNA lesions in B lymphocytes

Chen, Z., & Wang, J. H. (2014) · Frontiers of Medicine · doi:10.1007/s11684-014-0324-4 · Cited by 34

Structure of human DNA polymerase iota and the mechanism of DNA synthesis

Makarova, А. V., & Kulbachinskiy, A. V. (2012) · Biochemistry (Moscow) · doi:10.1134/s0006297912060016 · Cited by 33

Replicative Bypass of Abasic Site in Escherichia coli and Human Cells: Similarities and Differences

Weerasooriya, S., Jasti, V. P., & Basu, A. K. (2014) · PLoS ONE · doi:10.1371/journal.pone.0107915 · Cited by 32

Synthesis of Oligodeoxyribonucleotides Containing Analogs of O6-Methylguanine and Reaction with O6-Alkylguanine-DNA Alkyltransferase

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Potential artifacts in the measurement of DNA deamination

Lim, K. S., Huang, S. H., Jenner, A. M., Wang, H., Tang, S. Y., & Halliwell, B. B. (2006) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2006.01.030 · Cited by 30

Thymidine glycol: the effect on DNA molecular structure and enzymatic processing

Dolinnaya, N. G., Kubareva, E. A., Romanova, E. A., Trikin, R. M., & Oretskaya, T. S. (2012) · Biochimie · doi:10.1016/j.biochi.2012.09.008 · Cited by 30

NEIL1 Is the Major DNA Glycosylase that Processes 5-Hydroxyuracil in the Proximity of a DNA Single-Strand Break

Parsons, J. L., Kavli, B., Slupphaug, G., & Dianov, G. L. (2007) · Biochemistry · doi:10.1021/bi0622569 · Cited by 30

Nutritional Carcinogenesis

National Cancer Institute (2020) · Definitions · doi:10.32388/de0377 · Cited by 29

Inaccurate DNA Synthesis in Cell Extracts of Yeast Producing Active Human DNA Polymerase Iota

Makarova, А. V., Grabow, C. E., Gening, L. V., Tarantul, V. Z., Tahirov, T. H., Bessho, T., & Pavlov, Y. I. (2011) · PLoS ONE · doi:10.1371/journal.pone.0016612 · Cited by 27

Effect of 8-oxoguanine and abasic site DNA lesions on in vitro elongation by human DNA polymerase ϵ in the presence of replication protein A and proliferating-cell nuclear antigen

Locatelli, G. A., Pospiech, H., Gac, N. T. L., van Loon, B., Hübscher, U., Parkkinen, S., Syväoja, J. E., & Villani, G. (2010) · Biochemical Journal · doi:10.1042/bj20100405 · Cited by 26

The Block of DNA Polymerase δ Strand Displacement Activity by an Abasic Site Can Be Rescued by the Concerted Action of DNA Polymerase β and Flap Endonuclease 1

Maga, G., van Loon, B., Crespan, E., Villani, G., & Hübscher, U. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m900759200 · Cited by 26

Deletion of Individual Ku Subunits in Mice Causes an NHEJ-Independent Phenotype Potentially by Altering Apurinic/Apyrimidinic Site Repair

Choi, Y. J., Li, H., Son, M. Y., Wang, X.-H., Fornsaglio, J. L., Sobol, R. W., Lee, M., Vijg, J., Imholz, S., Dollé, M. E. T., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0086358 · Cited by 24

Inosine Nucleobase Acts as Guanine in Interactions with Protein Side Chains

Hajnić, M., de Ruiter, A., Polyansky, A. A., & Žagrović, B. (2016) · Journal of the American Chemical Society · doi:10.1021/jacs.6b02417 · Cited by 23

Roles of Aag, Alkbh2, and Alkbh3 in the Repair of Carboxymethylated and Ethylated Thymidine Lesions

You, C., Wang, P., Nay, S. L., Wang, J., Dai, X., O'Connor, T. R., & Wang, Y. (2016) · ACS Chemical Biology · doi:10.1021/acschembio.6b00085 · Cited by 22

Nucleic acid reactivity and conformation I. Deamination of cytosine by nitrous acid

Shapiro, R., & Yamaguchi, H. (1972) · Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis · doi:10.1016/0005-2787(72)90150-5 · Cited by 21

N-Nitrosodimethylamine in the Kashmiri Diet and Possible Roles in the High Incidence of Gastrointestinal Cancers

Chikan, N. A., Shabir, N., Shaffi, S. M., Mir, M. R., & Patel, T. (2012) · Asian Pacific Journal of Cancer Prevention · doi:10.7314/apjcp.2012.13.3.1077 · Cited by 19

Assessment of the genotoxic potential of nitric oxide-induced guanine lesions by in vitro reactions with Escherichia coli DNA polymerase I

Nakano, T., Asagoshi, K., Terato, H., Suzuki, T., & Ide, H. (2005) · Mutagenesis · doi:10.1093/mutage/gei027 · Cited by 18

The somatic autosomal mutation matrix in cancer genomes

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Roles of the active site residues and metal cofactors in noncanonical base-pairing during catalysis by human DNA polymerase iota

Makarova, А. V., Ignatov, A., Miropolskaya, N., & Kulbachinskiy, A. V. (2014) · DNA repair · doi:10.1016/j.dnarep.2014.07.006 · Cited by 15

Tumor‐associated mutations in O6‐methylguanine DNA‐methyltransferase (MGMT) reduce DNA repair functionality

Lamb, K. L., Liu, Y., Ishiguro, K., Kwon, Y., Paquet, N., Sartorelli, A. C., Sung, P., Rockwell, S., & Sweasy, J. B. (2012) · Molecular Carcinogenesis · doi:10.1002/mc.21964 · Cited by 12

Human DNA glycosylase enzyme TDG repairs thymine mispaired with exocyclic etheno-DNA adducts

Goto, M., Shinmura, K., Matsushima, Y., Ishino, K., Yamada, H., Totsuka, Y., Matsuda, T., Nakagama, H., & Sugimura, H. (2014) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2014.07.044 · Cited by 12

Structure and conformational dynamics of base excision repair DNA glycosylases

Zharkov, D. O. (2007) · Molecular Biology · doi:10.1134/s0026893307050044 · Cited by 11

Tyrosyl-DNA phosphodiesterase 1 is a new player in repair of apurinic/apyrimidinic sites

Rechkunova, N. I., Lebedeva, N. A., & Lavrik, O. I. (2015) · Russian Journal of Bioorganic Chemistry · doi:10.1134/s106816201505012x · Cited by 7

Role of Ku antigen in the repair of apurinic/apyrimidinic sites in DNA

Kosova, A. A., Lavrik, O. I., & Khodyreva, S. N. (2015) · Molecular Biology · doi:10.1134/s0026893315010070 · Cited by 7

Dihaloalkanes and polyhaloalkenes.

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[Repair of bulky DNA damages--derivatives of polycyclic aromatic hydrocarbons].

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Mechanisms of Coronavirus Genome Stability As Potential Targets for Antiviral Drugs

Yuyukina, S. K., & Zharkov, D. O. (2022) · Herald of the Russian Academy of Sciences · doi:10.1134/s1019331622040256 · Cited by 2

Chronic and Acute Toxicities of Aflatoxins: Mechanisms of Action

Benkerroum, N. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17020423 · Cited by 591

Bacterial Response to Oxidative Stress and RNA Oxidation

Seixas, A. F., Quendera, A. P., Sousa, J. P. A., Silva, A. F. Q., Arraiano, C. M., & Andrade, J. M. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2021.821535 · Cited by 272

Focus on UV-Induced DNA Damage and Repair—Disease Relevance and Protective Strategies

Kciuk, M., Marciniak, B., Mojzych, M., & Kontek, R. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21197264 · Cited by 168

Next-generation DNA damage sequencing

Mingard, C., Wu, J., McKeague, M., & Sturla, S. J. (2020) · Chemical Society Reviews · doi:10.1039/d0cs00647e · Cited by 92

Mitochondrial reactive oxygen species cause major oxidative mitochondrial DNA damages and repair pathways

Huang, Z., Chen, Y., & Zhang, Y. (2020) · Journal of Biosciences · doi:10.1007/s12038-020-00055-0 · Cited by 96

Translesion and Repair DNA Polymerases: Diverse Structure and Mechanism

Yang, W., & Gao, Y. (2018) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-062917-012405 · Cited by 245

Lost in replication: DNA polymerases encountering non-instructive DNA lesions

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DNA repair: Polymerases for passing lesions

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Replication of Damaged DNA

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Suffering in silence: the tolerance of DNA damage

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