Factors that limit the quality, number and progress of randomised controlled trials

Cites (303)

Items 201–302 of 302

1. Unexpected difficulties in randomizing patients in a surgical trial: A prospective study comparing extracorporeal shock wave lithotripsy with open cholecystectomy
   P. W. Plaisier, Marjolein Y. Berger, René L. van der Hul, H. G. T. Nijs, R. Den Toom, Onno T Terpstra, HAYO A. BRUINING · 1994 · World Journal of Surgery
2. Blind man's bluff: Effectiveness and significance of psychotherapy and pharmacotherapy blinding procedures in a clinical trial.
   Kathleen M. Carroll, Bruce J. Rounsaville, Charla Nich · 1994 · Journal of Consulting and Clinical Psychology
3. Successful program for recovery of dropouts to a clinical trial
   Jeffrey L. Probstfield, Michael L. Russell, Janice C. Henske, Ron Reardon, William Insull · 1986 · The American Journal of Medicine
4. Minimizing the three stages of publication bias
   T. C. Chalmers · 1990 · JAMA
5. Parental Opinions about Biomedical Research in Children in Tours, France
   ELISABETH AUTRET, J.P. Dutertre, P. Barbier, A.‐P. Jonville‐Béra, F Pierre, Charles C. Berger · 2017 · Developmental Pharmacology and Therapeutics
6. The doctor's dilemma: physician participation in randomized clinical trials.
   K M Taylor · 1985 · PubMed
7. Contrasting clinical and statistical significance within the research setting
   Bruce R. Lindgren, Catherine L. Wielinski, Stanley M. Finkelstein, Warren J. Warwick · 1993 · Pediatric Pulmonology
8. Patients' preferences and randomised trials
   Thurstan B. Brewin, Hazel Thornton, Clare Bradley, Klim McPherson, SheilaM. Gore, WilliamA. Silverman, Douglas G. Altman · 1996 · The Lancet
9. Bias in Treatment Assignment in Controlled Clinical Trials
   1984 · New England Journal of Medicine
10. Program on surgical control of the hyperlipidemias (POSCH): Recruitment experience
    Hēnry Buchwald, John P. Matts, Betty J. Hansen, John M. Long, Laurie L. Fitch · 1987 · Controlled Clinical Trials
11. Reasons related to adherence in community-based field studies
    Jan R. Atwood, Joan E. Haase, Shirley Rees-McGee, George Blackwell, L. Giordano, D. Earnest, David Samuel Alberts, Edward T. Sheehan, J. Benedict, Mikel G. Aickin et al. · 1992 · Patient Education and Counseling
12. Bypass Angioplasty Revascularization Investigation: Patient screening, selection, and recruitment
    Martial G. Bourassa, Gary S. Roubin, Katherine M. Detre, George S. Sopko, Ronald J. Krone, Michael J. Attabuto, Preben Bjerregaad, Steven F. Boiling, Michael V. Herman, Robert L. Frye · 1995 · The American Journal of Cardiology
13. Economics in sample size determination for clinical trials
    David John Torgerson, Mandy Ryan, Julie Ratcliffe · 1995 · QJM
14. A study of diet and breast cancer prevention in Canada: why healthy women participate in controlled trials
    Heather J. Sutherland, Kathleen Carlin, William Harper, Lisa J Martin, Cary V. Greenberg, James E. Till, Norman F. Boyd · 1993 · Cancer Causes & Control
15. Recruiting healthy participants for a large clinical trial
    Cathy Rudick, Nicholas R. Anthonisen, Jure Manfreda · 1993 · Controlled Clinical Trials
16. Participant recruitment to the Lipid Research Clinics Coronary Primary Prevention Trial
    Reagan H. Bradford · 1987 · Controlled Clinical Trials
17. Some Problems With Clinical Trials
    Walter Lawrence · 1991 · Archives of Surgery
18. Critical review of the quality and development of randomized clinical trials (RCTs) and their influence on the treatment of advanced epithelial ovarian cancer
    Silvia Marsoni, Valter Torri, Anna Taiana, A. Gambino, Roberto Giuseppe Grilli, Paola Liati, M. G. Franzosi, Vanna Pistotti, Fabio Parazzini, F Focarile et al. · 1990 · Annals of Oncology
19. Recruitment in a primary care trial on smoking cessation.
    WILLIAM C. WADLAND, Hughes, R. H. Secker Walker, David Lee Bronson, James W. Fenwick · 1990 · PubMed
20. Physician participation in a randomized clinical trial for ocular melanoma.
    K M Taylor · 1992 · PubMed
21. The clinical characteristics of schizophrenic patients consenting or not consenting to a placebo controlled trial of antipsychotic medication
    J. T. Bowen, Thomas R. E. Barnes · 1994 · Human Psychopharmacology Clinical and Experimental
22. Research in general practice for smokers and excessive drinkers in Australia and the UK. II. Representativeness of the results
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23. Type II errors and ethics
    DAVID J. NEWELL · 1978 · BMJ
24. Recruitment rates and factors affecting recruitment for a clinical trial of a putative anti‐psychotic agent in the treatment of acute schizophrenia
    Joanna Bowen, Steven Richard Hirsch · 1992 · Human Psychopharmacology Clinical and Experimental
25. Monitoring clinical trials: Experience of, and proposals under consideration by, the cancer therapy committee of the British medical research council
    Mahesh Parmar, David Machin · 1993 · Statistics in Medicine
26. Fast-track publication at The Lancet
    David McNamee · 1998 · The Lancet
27. Avoiding the pitfalls of sponsored multicentre research in general practice.
    H A Waldron, R.F. Cookson · 1993 · BMJ
28. Are clinical trials a cost-effective investment?
    A. S. Detsky · 1989 · JAMA
29. Strategies for Accessment and Recruitment of Subjects for Nursing Research
    Judy M. Diekmann, Jane M. Smith · 1989 · Western Journal of Nursing Research
30. Recruitment experience in the Aspirin Myocardial Infarction Study
    James A. Schoenberger · 1987 · Controlled Clinical Trials
31. A reversal of fortune: Practical problems in the monitoring and interpretation of an EORTC breast cancer trial
    Richard J Sylvester, Harry G M M Bartelink, Robert D. Rubens, Eortc Breast Cancer Cooperative Group · 1994 · Statistics in Medicine
32. Consent and Randomized Clinical Trials: Are There Moral or Design Problems?
    Loretta M. Kopelman · 1986 · The Journal of Medicine and Philosophy A Forum for Bioethics and Philosophy of Medicine
33. Response to “inclusion of women and minorities in clinical trials and the NIH Revitalization Act of 1993 — The perspective of NIH clinical trialists”
    Otis Webb Brawley · 1995 · Controlled Clinical Trials
34. Feasibility of a telephone survey to recruit health maintenance organization members into a tamoxifen chemoprevention trial.
    Mary Beryl Daly, Janet Seay, Andrew M. Balshem, Caryn Lerman, P. F. Engstrom · 1992 · PubMed
35. Patient Experiences with Research In a Tertiary Care Setting
    Elaine Larson, Deborah B. McGuire · 1990 · Nursing Research
36. A comparison of recruitment methods for an osteoarthritis exercise study
    Brian T. Maurer, Steven I. Moreno, Amy R. Pickard, Brooke E. Wurst, Daniel K. Norden, H. Ralph Schumacher · 1995 · Arthritis & Rheumatism
37. An evaluation of physician determinants in the referral of patients for cancer clinical trials in the community setting.
    R Winn, Jeremy Miransky, Jon F. Kerner, L Kennelly, R A Michaelson, S R Sturgeon · 1984 · PubMed
38. Patients' perceived understanding of informed consent in investigational drug studies
    Roberta M. Tankanow, Burgunda V. Sweet, Jill A. Weiskopf · 1992 · American Journal of Health-System Pharmacy
39. Variations in breast cancer treatment decisions and their impact in mounting trials
    Raisa Berlin Deber, Gail G. Thompson · 1990 · Controlled Clinical Trials
40. Incentives and Rewards for Subjects in Nursing Research
    NANCY MARGARET WINEMAN, Ellen J. Durand · 1992 · Western Journal of Nursing Research
41. Reporting randomized controlled trials. An experiment and a call for responses from readers
    D. Rennie · 1995 · JAMA
42. Randomized Clinical Trials
    Marilyn S. Fetter, SUZANNE L. FEETHAM, KAREN D??APOLITO, Chaze Ba, ARLENE FINK BARBARA B. FRINK, MARGARET K. HOUGHART, CINDY HYLTON RUSHTON · 1989 · Nursing Research
43. The effect of poor compliance and treatment side effects on sample size requirements in randomized clinical trials
    Kenneth B. Schechtman, Mae O. Gordon · 1994 · Journal of Biopharmaceutical Statistics
44. Clinical trials
    Jill S. Ratain, Marc C. Hochberg · 1990 · Arthritis & Rheumatism
45. Patient accrual and quality of participation in a multicentre study on myeloma: a comparison between major and minor participating centres
    Martin Hjorth, Erik C. Holmberg, Stig Rödjer, Adam Taube, Jan Westin · 1995 · British Journal of Haematology
46. Absolutely relative: How research results are summarized can affect treatment decisions
    Raymond F. Zambito · 1992 · Journal of Oral and Maxillofacial Surgery
47. The Atlantic gap: Clinical trials in Europe and the United States
    Marc Ansseau · 1992 · Biological Psychiatry
48. Protocol reviews at The Lancet
    David McNamee · 1997 · The Lancet
49. Selection of Patients for Clinical Trials
    Alastair Compston · 1987 · Neuroepidemiology
50. The perspective of patients with vascular disease on participation in clinical trials.
    M Wilcox, Sally Schroer · 1994 · PubMed
51. Methodological and Design Issues in Clinical Trials of New Neuroleptics: an Overview
    A. George Awad · 1993 · The British Journal of Psychiatry
52. Blinding and exclusions after allocation in randomised controlled trials: survey of published parallel group trials in obstetrics and gynaecology
    1996 · International Journal of Gynecology & Obstetrics
53. Clinical Research in the NHS Today
    Christopher John Dickinson · 1994 · Journal of the Royal College of Physicians of London
54. Improving the validity of clinical exercise testing: the relationship between practice and performance.
    Elizabeth Dean, Jocelyn Ross, J Bartz, S Purves · 1989 · PubMed
55. A GENERALIZED LINEAR MODEL FOR ANALYSING RECEIVER OPERATING CHARACTERISTIC CURVES
    PHILIP J. SMITH, Theodore J. Thompson, Michael Maurice Engelgau, William H. Herman · 1996 · Statistics in Medicine
56. Commentary: Placebo run ins have some value
    Lawrence E Ramsay · 1997 · BMJ
57. Trials and tribulations of multicenter studies
    Ronald J. Hogg · 1991 · Pediatric Nephrology
58. Relation of sociodemographic, clinical, and quality-of-life variables to adherence in the cardiac arrhythmia suppression trial.
    ELEANOR B. SCHRON, Maria M. Brooks, Larry Gorkin, Joyce C. Kellen, Margaret J. Morris, Jeanne Campion, Sally Ann Shumaker, Jacqueline Corum · 1996 · PubMed
59. Carotid endarterectomy vs carotid angioplasty
    Martin M. Brown, Graham S Venables, Andy Clifton, P.A. Gaines, Robert S. Taylor · 1997 · The Lancet
60. Planning and implementing clinical trials
    Teresa J. Melink, Margaret Y. Whitacre · 1991 · Seminars in Oncology Nursing
61. Patient Registration and Treatment Allocation in Multicenter Clinical Trials Using a FAX-OCR System
    T Kamakura, Masumi Sakamoto, Tomohiro Odaka, Yukari NOSE, Kaho Akazawa · 1994 · Methods of Information in Medicine
62. Selection of patients for psoriasis clinical trials: a survey of the recent dermatological literature
    Petersen Lj, Kristensen Jk · 1992 · Journal of Dermatological Treatment
63. Relationship between rate of patient enrollment and quality of clinical center performance in two multicenter trials in ophthalmology
    Barbara S. Hawkins, Mary Jane Prior, Marian R. Fisher, Dawn W. Blackhurst · 1990 · Controlled Clinical Trials
64. Clinical trials of informed consent
    David L. Simel · 1992 · Controlled Clinical Trials
65. Commentary regarding “inclusion of women and minorities in clinical trials and the NIH Revitalization Act of 1993 — the perspective of NIH clinical trialists”
    Steven Piantadosi · 1995 · Controlled Clinical Trials
66. The inclusion of women in clinical trials of antihypertensive medications: A review of twenty-four trials in one pharmacology journal
    Janice D. Nunnelee · 1995 · Journal of Vascular Nursing
67. Selection of patients for randomised trials: a study based on the MACOP‐B vs CHOP in NHL study
    Janey M. Stone, Christine R. Laidlaw, F Page, I. A. Cooper · 1994 · Australian and New Zealand Journal of Medicine
68. An analysis of randomized controlled trials published in the US family medicine literature, 1987-1991.
    Chris A. Silagy, D Jewell, David Mant · 1994 · PubMed
69. Development of a contingency recruitment plan for a phase III chemoprevention trial of cervical dysplasia.
    Lois J. Loescher, Graham Ve, Mikel G. Aickin, Frank L. Meyskens, Surwit Ea · 1990 · PubMed
70. Funding research and development in the NHS
    M Drummond, Barbara J. Crump, Vincent Little · 1992 · The Lancet
71. Objectives of QC systems and QA function in clinical research.
    Elisabeth Poy · 1993 · PubMed
72. Trials and tribulations
    Desmond G. Julian · 1994 · Cardiovascular Research
73. Is proper methodology associated with the use of a clinically relevant outcome measure? The case of randomized clinical trials on medical treatment of open-angle glaucoma.
    Luca Mario Rossetti, Ilaria Marchetti, N. Orzalesi, Nicola Scorpiglione, Anna Marina Liberati · 1993 · PubMed
74. Discussion of “inclusion of women and minorities in clinical trials and the NIH Revitalization Act of 1993 — The perspective of NIH clinical trialists”
    Robert F. Woolson, Martha F. Jones, William R. Clarke, James C. Torner · 1995 · Controlled Clinical Trials
75. Requirements for controlled clinical trials of preoperative cardiovascular risk reduction
    Mylan C. Cohen, Carol McKenna, Stanley M. Lewis, James E. Muller · 1995 · Controlled Clinical Trials
76. Patient preferences and randomised clinical trials
    John R. F. Gladman, David H Barer · 1989 · BMJ
77. Triangular test and randomized trials: Practical problems in a small cell lung cancer trial
    Jean‐Pierre Pignon, Michèle Tarayre, Ariane Auquier, Rodrigo Arriagada, Thierry Le Chevalier, Pierre Ruffiè, Alain Rivière, I. Monnet, Pierre Chomy, Claude Tuchais · 1994 · Statistics in Medicine
78. Conceptual and Methodologic Problems in the Evaluation of a New Burn Treatment Modality
    D. W. Coombs, Alan R. Dimick, JANET M. BRONSTEIN, Linda H. Potts, B Bowens · 1993 · Journal of Burn Care & Rehabilitation
79. Evaluation of the methodological quality of clinical trial protocols
    Carles García-Cases, André Geraldo da Silva Duque, Javier Borja, Iñaki Izquierdo, V. De la Fuente, Josep Torrent-Farnell, F Jané · 1993 · European Journal of Clinical Pharmacology
80. Issues of enrollment bias in cancer chemoprevention trials
    Karen Suchanek Hudmon, Anita Yeomans Kinney · 1995 · The Cancer bulletin of the University of Texas M.D. Anderson Hospital and Tumor Institute at Houston
81. Interactions between Stroke Data Banks and Clinical Trials
    Ralph L. Sacco · 1994 · Neuroepidemiology
82. Clinical trials to study pain in patients with advanced cancer: practical difficulties
    Ian G. Kerr · 1995 · Anti-Cancer Drugs
83. Overcoming “Trial Fatigue”: A Strategy for Optimizing Patient Accrual Speed and Resource Utilization
    Gunther Winkler, Elizabeth A. Levin, Evelyn Y. Whalen, John Larus · 1996 · Drug Information Journal
84. Medical Editors' Trial Amnesty
    Robin Fox · 1998 · Journal of the Royal Society of Medicine
85. ASSESSMENT OF STUDY DESIGN IN CLINICAL TRIALS FOR BLADDER CANCER
    Ian F. Tannock · 1992 · Urologic Clinics of North America
86. Trials and tribulations: patients' perspectives of the Betaseron study.
    W Morrison · 1994 · PubMed
87. Randomized Clinical Trials on Medical Treatment of Glaucoma: Are They Appropriate to Guide Clinical Practice?
    Roger Vogel · 1994 · Archives of Ophthalmology
88. Statistical Problems in the Design of Antiarrhythmic Drug Trials
    Lawrence M. Friedman, ELEANOR B. SCHRON · 1992 · Journal of Cardiovascular Pharmacology
89. Statistical Problems in the Design of Antiarrhythmic Drug Trials
    Lawrence M. Friedman, ELEANOR B. SCHRON · 1992 · Journal of Cardiovascular Pharmacology
90. Who Is in Charge? Investigator and Sponsor Alliances
    Jan van Gijn · 1995 · Cerebrovascular Diseases
91. Prostate Cancer Intervention Versus Observation Trial: economic analysis in study design and conditions of uncertainty.
    Schwartz Js · 1995 · PubMed
92. Quality assurance in phase II and III studies.
    Wood Dj · 1993 · PubMed
93. Practical problems of undertaking clinical trials in the community
    V. Banks, Sue Bale · 1994 · Journal of Wound Care
94. Interpreting physician participation in randomized clinical trials: The physician orientation profile
    1987 · Controlled Clinical Trials
95. Carotid endarterectomy vs carotid angioplasty
    Charles P Warlow, Peter AG Sandercock · 1997 · The Lancet
96. Understanding and evaluating clinical trials
    Bruce G Howard · 1996 · Journal of the American Academy of Dermatology
97. Impact of the NIH inclusion Guidelines
    Wendy Baldwin · 1995 · Controlled Clinical Trials
98. Too Stringent Patient Selection Criteria in a Clinical Trial of Alpha-Blockers Reduce the Value of the Results
    T.P. Rosenbaum, P.J.R. Shaw · 1991 · European Urology
99. Quality of life for asthma patients : an existential-aesthetic theory.
    Neil Drummond · 1997 · OpenGrey (Institut de l'Information Scientifique et Technique)
100. The Jungle of Acute Stroke Trials, Trialists and Sponsors
     Julien Bogousslavsky · 1995 · Cerebrovascular Diseases
101. Patient and Clinical Site Compliance: Preparing User-Friendly Clinical Trial Materials
     Martin L. Jeiven, Martin L. Jeiven · 1994 · Clinical Research and Regulatory Affairs
102. Single-agent chemotherapy trials in small-cell lung cancer, 1970 to 1990: The case for studies in previously treated patients
     Grant SC · 1992 · Lung Cancer