The DOI matches its Crossref record; 54 of the 54 references it cites were found in a registry or an index.
Soft Tissue Sarcomas
Open accessAbstract
Sarcomas are a heterogeneous group of rare tumors that arise predominantly from the embryonic mesoderm. They present most commonly as an asymptomatic mass originating in an extremity but can occur anywhere in the body, particularly the trunk, retroperitoneum, or the head and neck. Pretreatment radiologic imaging is critical for defining the local extent of a tumor, staging the disease, guiding biopsies, and aiding in diagnosis. Core-needle biopsy is the preferred biopsy technique for diagnosing soft tissue sarcomas. The American Joint Committee on Cancer (AJCC) staging system for soft tissue sarcomas is based on histologic grade, the tumor size and depth, and the presence of distant or nodal metastases. Despite improvements in local control rates with wide local resections and radiation therapy, metastasis and death remain a significant problem in 50% of patients who present with high-risk soft tissue sarcomas. The most common site of metastasis is the lungs, and metastasis generally occurs within two to three years after the completion of therapy. Progress in the molecular characteristics of these tumors should in the near future translate into molecularly based therapies that can be incorporated into standard treatment strategies.
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Cites
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Cited by
Yang, J. C., Chang, A. E., Baker, A. R., Sindelar, W. F., Danforth, D. N., Topalian, S. L., DeLaney, T., Glatstein, E., Steinberg, S. M., Merino, M. J., et al. (1998) · Journal of Clinical Oncology · doi:10.1200/jco.1998.16.1.197 · Cited by 1,541
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MDM2 Promotes Proteasome-Dependent Ubiquitin-Independent Degradation of Retinoblastoma Protein
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Trabectedin: A Review of its Use in the Management of Soft Tissue Sarcoma and Ovarian Cancer
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Metadata
- Authors
- Cormier, J. N., & Pollock, R. E.
- Venue
- CA: A Cancer Journal for Clinicians
- Publisher
- Wiley
- Published
- 2004-03-01
- Volume
- 54
- Issue
- 2
- Pages
- 94-109
- ISSN
- 0007-9235 (ISSN-L)
- OpenAlex
- W2020617188
- Cited by
- 835
- References
- 54
- FWCI
- 29.41
- Type
- journal article
- Language
- en
- Open access
- gold
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
