The DOI matches its Crossref record; 76 of the 76 references it cites were found in a registry or an index.
Therapy-related leukemia and myelodysplasia: susceptibility and incidence
Open accessAbstract
Therapy-related myelodysplastic syndrome/acute myeloid leukemia (t-MDS/AML) is an increasingly recognized treatment complication in patients treated with radiotherapy or chemotherapy for previous hematologic malignancies or solid tumors. Distinct clinical entities have been described according to the primary treatment, corresponding to defined genetic lesions. Chromosome 7 and/or 5 losses or deletions are typical of alkylating agent-induced AML, while development of t-AML with balanced translocations involving chromosome bands 11q23 and 21q22 has been related to previous therapy with drugs targeting DNA-topoisomerase II. In addition, antimetabolites, and in particular the immunosuppressant azathioprine, have been shown to induce defective DNA-mismatch repair. This could promote survival of misrepaired cells giving rise to the leukemic clone. Individual predisposing factors, including polymorphisms in detoxification and DNA repair enzymes have been identified. Their combination may significantly increase the risk of t-MDS/AML. Among patients with hematologic malignancies, long-term survivors of Hodgkin's lymphoma are exposed to an increased risk of t-MDS/AML, particularly when receiving MOPP-based, and escalated BEACOPP regimens, and when alkylators are combined with radiotherapy. Patients with Hodgkin's and non-Hodgkin's lymphoma are at highest risk when total body irradiation followed by autologous stem cell transplantation is used as rescue or consolidation therapy. The addition of granulocyte-colony-stimulating factor and radiotherapy plays a significant role in t-AML following treatment of children with acute lymphoblastic leukemia. In non-hematologic malignancies, treatment for breast cancer and germ-cell tumors has been associated with a 1-5% lifetime risk of both lymphoid as well as myeloid leukemia. In all cases the risk of t-MDS/AML drops sharply by 10 years after treatment.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Secondary cancers are frequently acute myeloid leukaemias 155 , which may be caused by previous exposure to DNA-damaging alkylators, often arising after a median of around 7 years after initial treatment 158 .”
From Osteosarcoma (2022) · cites this paper as [158]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Edwards, B. K., Brown, M. L., Wingo, P. A., Howe, H. L., Ward, E., Ries, L. A. G., Schrag, D., Jamison, P. M., Jemal, A., Wu, X. C., et al. (2005) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/dji289 · Cited by 955
Hydroxyurea Compared with Anagrelide in High-Risk Essential Thrombocythemia
Harrison, C. N., Campbell, P. J., Buck, G. A. N., Wheatley, K., East, C. L., Bareford, D., Wilkins, B. S., van der Walt, J. D., Reilly, J. T., Grigg, A., et al. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa043800 · Cited by 921
Smith, S. M., Beau, M. M. L., Huo, D., Karrison, T. G., Sobecks, R. M., Anastasi, J., Vardiman, J. W., Rowley, J. D., & Larson, R. A. (2003) · Blood · doi:10.1182/blood-2002-11-3343 · Cited by 681
Hematotoxicity in Workers Exposed to Low Levels of Benzene
Qing Lan, B., Zhang, L., Li, G., Vermeulen, R. C. H., Weinberg, R. S., Dosemeci, M., Rappaport, S. M., Shen, M., Alter, B. P., Wu, Y., et al. (2004) · Science · doi:10.1126/science.1102443 · Cited by 651
Environment and Cancer: Who Are Susceptible?
Perera, F. P. (1997) · Science · doi:10.1126/science.278.5340.1068 · Cited by 638
Finazzi, G. (2004) · Blood · doi:10.1182/blood-2004-09-3426 · Cited by 433
Pharmacogenomics, Regulation and Signaling Pathways of Phase I and II Drug Metabolizing Enzymes
Rushmore, T. H., & Kong, A.-N. T. (2002) · Current Drug Metabolism · doi:10.2174/1389200023337171 · Cited by 425
Secondary leukemias induced by topoisomerase-targeted drugs
Felix, C. A. (1998) · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · doi:10.1016/s0167-4781(98)00139-0 · Cited by 416
Sterkers, Y., Preudhomme, C., Laï, J., Demory, J., Caulier, M. T., Wattel, E., Bordessoule, D., Bauters, F., & Fenaux, P. (1998) · Blood · doi:10.1182/blood.v91.2.616 · Cited by 369
Homologous repair of DNA damage and tumorigenesis:the BRCA connection
Jasin, M. (2002) · Oncogene · doi:10.1038/sj.onc.1206176 · Cited by 363
Research works printed but not linked: 4
- Felix CA, Walker AH, Lange BJ, Williams TM, Winick NJ, Cheung NK, et al. Association of CYP3A4 genotype with treatment-related leukemia. Proc Natl Acad Sci USA 1998;95:13176-81.
- Pui CH, Ribeiro RC, Hancock ML, Rivera GK, Evans WE, Raimondi SC, et al. Acute myeloid leukemia in children treated with epipodophillotoxins for acute lymphocytic leukemia. N Engl J Med 2001;325,1682-7.
- Cuzick J, Erskine S, Edelman D, Galton DA. A comparison of the inci- dence of the myelodisplasic syndrome and acute myeloid leukemia following melphalan and cyclophosphamide treatement for myelomatosis. Br J Cancer 1987;55:523-9.
- Harrison CN, Campbell PJ, Buck G, Wheatley K, East CL, Bareford D, et al. Hydroxyurea compared with anagre- lide in high-risk essential thrombocy- themia. N Engl J Med 2005;353: 33-45.
Cited by
Sorted by citations
Items 101–200 of 235
Childhood Exposures and Risk of Malignancy in Adulthood
Chang, V. Y., & Davidson, T. B. (2015) · Pediatric Annals · doi:10.3928/00904481-20151112-10 · Cited by 8
CLONAL HEMATOPOIESIS: ROLE IN HEMATOLOGIC NON-HEMATOLOGIC
Testa, U., Castelli, G., & Pelosi, E. (2022) · Mediterranean Journal of Hematology and Infectious Diseases · doi:10.4084/mjhid.2022.069 · Cited by 9
Bendle, M., Pealing, J., Papanastasopoulos, P., & Bower, M. (2014) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-014-2538-1 · Cited by 8
SIMILARITIES OF ELDERLY AND THERAPY-RELATED AML
D’Alò, F., Fianchi, L., Fabiani, E., Criscuolo, M., Greco, M., Guidi, F., Pagano, L., Leone, G. G. M., & Voso, M. T. (2011) · Mediterranean Journal of Hematology and Infectious Diseases · doi:10.4084/mjhid.2011.052 · Cited by 8
Self-citationSingh, A., Herr, M. M., Griffiths, E. A., Przespolewski, A., Faber, M. G., Mrad, C., Wang, E. S., Hahn, T., & Thota, S. (2021) · Scientific Reports · doi:10.1038/s41598-021-02497-4 · Cited by 8
Acute lymphoblastic leukaemia in a child with systemic lupus erythematosus
Gökçe, M., Buluş, D., Bilginer, Y., Gümrük, F., Beşbaş, N., & ÇETİN, M. (2012) · Lupus · doi:10.1177/0961203312436859 · Cited by 7
Kim, Y., Cho, S. Y., Park, T. S., Oh, S. H., & Yoon, H. J. (2011) · PubMed · Cited by 8
Tanizawa, R. S. D. S., Kumeda, C. A., Azevedo, R. S., Leal, A., Ferreira, P. D. B., & Velloso, E. D. R. P. (2011) · Revista Brasileira de Hematologia e Hemoterapia · doi:10.5581/1516-8484.20110117 · Cited by 8
Non-Small Cell Lung Cancer Resection in Lymphoma Patients
Kim, M. P., Correa, A. M., Swisher, S. G., Hofstetter, W. L., Mehran, R. J., Rice, D. C., Walsh, G. L., Erasmus, J. J., Moran, C. A., Vaporciyan, A. A., et al. (2010) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2010.02.114 · Cited by 8
Yang, D., Fu, X., Zhang, X., Li, W., & Zhang, M. (2015) · Oncology Letters · doi:10.3892/ol.2015.3703 · Cited by 8
Kulkarni, B., AlOtaiby, S., Khashab, N. M., & Hadjichristidis, N. (2025) · Biomacromolecules · doi:10.1021/acs.biomac.5c00102 · Cited by 7
Bobadilla‐Morales, L., Pimentel‐Gutiérrez, H. J., Gallegos‐Castorena, S., Paniagua-Padilla, J. A., Ortega‐de-la-Torre, C., Sanchez-Zubieta, F. A., Silva‐Cruz, R., Corona‐Rivera, J. R., Zepeda‐Moreno, A., Gonzalez-Ramella, O. R., et al. (2015) · Molecular Cytogenetics · doi:10.1186/s13039-014-0105-4 · Cited by 7
Chromosomal analysis of myelodysplastic syndromes among atomic bomb survivors in Nagasaki
Horai, M., Satoh, S., Matsuo, M., Iwanaga, M., Horio, K., Jo, T., Takasaki, Y., Kawaguchi, Y., Tsushima, H., Yoshida, S., et al. (2017) · British Journal of Haematology · doi:10.1111/bjh.15050 · Cited by 7
Akiyoshi, M., Hisasue, M., Asakawa, M. G., Neo, S., & Akiyoshi, M. (2022) · Veterinary Clinical Pathology · doi:10.1111/vcp.13086 · Cited by 7
Myelodysplastic Syndromes: Challenges to Improving Patient and Caregiver Satisfaction
Smith, B. D. (2012) · The American Journal of Medicine · doi:10.1016/j.amjmed.2012.04.020 · Cited by 7
Integrated genomics of susceptibility to alkylator-induced leukemia in mice
Cahan, P., & Graubert, T. A. (2010) · BMC Genomics · doi:10.1186/1471-2164-11-638 · Cited by 8
SWR/J mice are susceptible to alkylator-induced myeloid leukemia
Janke, M. R., Baty, J., & Graubert, T. A. (2013) · Blood Cancer Journal · doi:10.1038/bcj.2013.59 · Cited by 7
Commentary on “Clinical Presentation, Diagnosis, and Prognosis of Myelodysplastic Syndromes”
Repasy, A. (2012) · The American Journal of Medicine · doi:10.1016/j.amjmed.2012.04.016 · Cited by 7
Myeloproliferative Neoplasms: Challenging Dogma
Spivak, J. L. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13226957 · Cited by 6
Preleukemic Fusion Genes Induced via Ionizing Radiation
Košík, P., Škorvaga, M., & Belyaev, I. Y. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24076580 · Cited by 6
Bang, J.-I., Lee, E. S., Kim, T. S., & Kim, S.-K. (2014) · Nuclear Medicine and Molecular Imaging · doi:10.1007/s13139-014-0302-4 · Cited by 6
Structural and Expression Changes of Septins in Myeloid Neoplasia
Cerveira, N., Santos, J., & Teixeira, M. R. (2009) · Critical Reviews™ in Oncogenesis · doi:10.1615/critrevoncog.v15.i1-2.40 · Cited by 6
Bravo, M. M. E., Peralta, M., Neira, V. P., & Itriago, G. L. (2013) · Revista Médica Clínica Las Condes · doi:10.1016/s0716-8640(13)70198-6 · Cited by 8
Myelodysplasia in the Wellington region 2002–2007: disease incidence and treatment patterns
Irwin, J. R., D'Souza, A., Johnson, L., & Carter, J. (2011) · Internal Medicine Journal · doi:10.1111/j.1445-5994.2011.02443.x · Cited by 6
Sella, T., & Stone, R. M. (2018) · Gynecologic Oncology · doi:10.1016/j.ygyno.2018.10.013 · Cited by 6
Matnani, R. G., Parekh, V., Borate, U., Brazelton, J. D., Reddy, V., & Peker, D. (2015) · Pathology International · doi:10.1111/pin.12337 · Cited by 6
Yokoyama, H., Mori, S., Kobayashi, Y., Kurosawa, S., Saito, B., Fuji, S., Maruyama, D., Azuma, T., Kim, S. W., Watanabe, T., et al. (2010) · International Journal of Hematology · doi:10.1007/s12185-010-0640-7 · Cited by 6
Asurappulige, H. S. H., Thomas, A. D., & Morse, H. (2023) · Mutagenesis · doi:10.1093/mutage/gead018 · Cited by 5
Esquissato, G. N. M., de Sant’Anna, J. R., Franco, C. C. S., ROSADA, L. J., SANTOS, P. A. S. R. D., & de Castro‐Prado, M. A. A. (2014) · Anais da Academia Brasileira de Ciências · doi:10.1590/0001-3765201420130106 · Cited by 5
Abnormalities in Chromosomes 5 and 7 in Myelodysplastic Syndrome and Acute Myeloid Leukemia
Kendrick, T. S., Buic, D., Fuller, K. A., & Erber, W. N. (2025) · Annals of Laboratory Medicine · doi:10.3343/alm.2024.0477 · Cited by 7
Tokuhira, M., Kimura, Y., Nemoto, T., Sagawa, M., Tomikawa, T., Sakai, R., Okuyama, A., Amano, K., Higashi, M., Tamaru, J., et al. (2014) · Journal of the Japan Society of the Reticuloendothelial System · doi:10.3960/jslrt.54.137 · Cited by 5
Therapy-Related Acute Myeloid Leukemias
Guenova, M. L., Balatzenko, G. N., & Mihaylov, G. G. (2013) · InTech eBooks · doi:10.5772/52459 · Cited by 6
Shimada, N., Ohno, N., Tanosaki, R., Fuji, S., Suzuki, Y., Yuji, K., Uchimaru, K., & Tojo, A. (2017) · Internal Medicine · doi:10.2169/internalmedicine.56.7763 · Cited by 5
Ojima, M., Hirouchi, T., Etani, R., Ariyoshi, K., Fujishima, Y., & Kai, M. (2019) · Radiation Research · doi:10.1667/rr15359.1 · Cited by 4
Akiyama, H., Yamamoto, M., Sakashita, C., Umezawa, Y., Kurosu, T., Murakami, N., & Miura, O. (2015) · Internal Medicine · doi:10.2169/internalmedicine.54.3535 · Cited by 4
Felix, C. A. (2006) · Cambridge University Press eBooks · doi:10.1017/cbo9780511471001.032 · Cited by 4
Optimizing Chemotherapy Regimens for Patients With Early-Stage Breast Cancer
Dotan, E., & Goldstein, L. J. (2010) · Clinical Breast Cancer · doi:10.3816/cbc.2010.s.002 · Cited by 4
Role of Hematopoietic Stem Cell Transplantation in the Treatment of Non-Hodgkin’s Lymphoma
Bierman, P. J., & Phillips, G. L. (2008) · Cancer treatment and research · doi:10.1007/978-0-387-78580-6_15 · Cited by 4
Predictors of Multiple Primary Malignancies: Literature Review
Султанбаев, А. В., Меньшиков, К. В., Мусин, Ш. И., Измайлов, А. А., Menshikovа, I. A., & Султанбаева, Н. И. (2023) · Creative Surgery and Oncology · doi:10.24060/2076-3093-2023-13-3-221-228 · Cited by 3
Iatsyshyna, A. P. (2012) · Biopolymers and Cell · doi:10.7124/bc.000032 · Cited by 3
Dysplastic nevus syndrome and pancreatic cancer: A case report
Popa, L. G., Giurcăneanu, C., Niţipir, C., Popa, A. M., Stoica, C., Beiu, C., Tebeică, T., Negoita, S. I., & Mihai, M. M. (2021) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2021.10953 · Cited by 3
Fante, M. A., Harrer, D. C., Zartner, B., Lüke, F., Mayer, S., Menhart, K., Reichle, A., Herr, W., Vogelhuber, M., & Heudobler, D. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1177330 · Cited by 3
Patil, L. S., Patil, V. L., Giraddi, T., Desai, K., & Gautam, A. (2014) · International Journal of Biomedical and Advance Research · doi:10.7439/ijbar.v5i9.863 · Cited by 3
Chronic Myeloid Leukemia Developing After Successful Treatment of Acute Promyelocytic Leukemia
Huang, F., Chang, J., Du, C., & Tao, R. (2015) · Indian Journal of Hematology and Blood Transfusion · doi:10.1007/s12288-015-0544-z · Cited by 3
Niscola, P. (2013) · Mediterranean Journal of Hematology and Infectious Diseases · doi:10.4084/mjhid.2013.030 · Cited by 3
Favourable prognostic factors in therapy related acute myeloid leukaemia
Antonijevic, N. M., Suvajdžić, N., Terzić, T., Jakovljević, B. D., Janković, G., Elezović, I. V., Milošević, R., & Čolović, M. (2011) · Srpski arhiv za celokupno lekarstvo · doi:10.2298/sarh1106347a · Cited by 3
Doi, K., Asano, T., & Kinoshita, T. (2010) · Nippon Jibiinkoka Gakkai Kaiho · doi:10.3950/jibiinkoka.113.556 · Cited by 3
Acute myeloid leukemia after kidney transplantation: a case report and literature review
Cardarelli, F., Bijol, V., Chandraker, A. K., Varga, C., & Riella, L. V. (2016) · Brazilian Journal of Nephrology · doi:10.5935/0101-2800.20160072 · Cited by 3
Shoumariyeh, K., Jung, J., Rassner, M. P., Dold, S. M., Riebl, V., Pantić, M., Herget, G. W., Marks, R., Lübbert, M., Wäsch, R., et al. (2021) · Annals of Hematology · doi:10.1007/s00277-021-04490-3 · Cited by 3
Pitts, E., Grainger, B. T., McKenzie, D., & Fiorenza, S. (2025) · Microorganisms · doi:10.3390/microorganisms13102302 · Cited by 2
Subsequent primary cancer risks for non-hereditary colorectal cancer survivors
Aung, Y. K., Jenkins, M. A., Baxter, N. N., Potter, J. D., Schmit, S. L., Samadder, J. J., Newcomb, P. A., Buchanan, D. D., & Win, A. K. (2026) · EClinicalMedicine · doi:10.1016/j.eclinm.2025.103716 · Cited by 2
5′-Azacitidine for therapy-related myelodysplastic syndromes after non-Hodgkin lymphoma treatment
Breccia, M., Salaroli, A., Loglisci, G., Martelli, M., D’Elia, G. M., Nanni, M., Mauro, F. R., & Alimena, G. (2011) · Leukemia Research · doi:10.1016/j.leukres.2011.05.030 · Cited by 2
Xu, M., Yang, Y., Fu, X., Li, C., Zhou, J., Li, M., & Xu, D. (2015) · Chemotherapy Open access · doi:10.4172/2167-7700.1000182 · Cited by 2
Consenso de leucemia mieloide aguda en México
Arana-Luna, L. L., Alvarado‐Ibarra, M., Silva-Michel, L. G., Morales-Maravilla, A., González-Rubio, M. D. C., Chavez-Aguilar, L. A., Tena-Iturralde, M. F., Mojica-Balderas, L., Zapata-Canto, N. P., Galindo-Delgado, P., et al. (2022) · Gaceta Médica de México · doi:10.24875/gmm.m21000597 · Cited by 2
Response of the Bone Marrow Stem Cells and the Microenvironment to Stress
Uçkan, D., & Muratoğlu, B. (2022) · Springer eBooks · doi:10.1007/978-981-19-2655-6_22 · Cited by 2
Multidrug Resistance Mechanism of Acute Lymphoblastic Leukemia
Su, Z., Zhu, H., Liu, Y., Yuan, H., Yin, J., & Xu, H. (2011) · InTech eBooks · doi:10.5772/26488 · Cited by 2
Simultaneous Occurrence of Advanced Neuroblastoma and Acute Lymphoblastic Leukemia: A Case Report
Pedram, M., Vafaie, M., Jaseb, K., Fekri, K., & Haghi, S. (2011) · Middle East journal of cancer · Cited by 2
Chen, Y., Hsieh, Y., Lin, S., Kuo, S., Liu, C., Hwang, W., Huang, W., Feng, Y., Chuang, S., & Lin, C. (2011) · The Kaohsiung Journal of Medical Sciences · doi:10.1016/j.kjms.2011.06.026 · Cited by 2
Lyman, G. H., & Kuderer, N. M. (2010) · Cancer treatment and research · doi:10.1007/978-1-4419-7073-2_10 · Cited by 2
Coexistence of Chronic Lymphocytic Leukemia and Acute Myeloid Leukemia
Milošević, I. (2016) · Turkish Journal of Hematology · doi:10.4274/tjh.2016.0106 · Cited by 2
Consensus in acute myeloid leukemia in Mexico
Arana-Luna, L. L., Alvarado‐Ibarra, M., Silva-Michel, L. G., Morales-Maravilla, A., González-Rubio, M. D. C., Chávez-Aguilar, L. A., Tena-Iturralde, M. F., Mojica-Balceras, L., Zapata-Canto, N., Galindo-Delgado, P., et al. (2022) · Gaceta Médica de México · doi:10.24875/gmm.m21000598 · Cited by 2
Complex cytogenetic findings in the bone marrow of a chronic idiopathic myelofibrosis patient
Balcı, T. B., Yüksel, M. K., Yılmaz, Z., & Şahin, F. İ. (2010) · Turkish Journal of Hematology · doi:10.5152/tjh.2010.09 · Cited by 2
Acute erythroid leukemia in a child: insights from a rare case
Gupta, L. (2025) · American Journal of Blood Research · doi:10.62347/gcug1405 · Cited by 1
Uekusa, R., Yokoi, A., Watanabe, E., Inoue, M., Mizuno, K., Yoshida, K., Yoshikawa, N., Niimi, K., Suzuki, S., & Kajiyama, H. (2026) · Frontiers in Oncology · doi:10.3389/fonc.2026.1728766 · Cited by 1
Tai, W., Kim, D., Dib, J., Thomas, J., Gopishetty, S., Idogun, P., Anyadibe, A., Ayetoran, A., Zaidi, S., Balaraman, S., et al. (2026) · Cureus · doi:10.7759/cureus.103706 · Cited by 1
Aung, Y. K., Zhang, Y., Baxter, N. N., Jenkins, M. A., & Win, A. K. (2026) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-26-0386 · Cited by 1
ABVD vs. radiotherapy in early stage Hodgkin’s lymphoma
Wenz, F. K., Abo‐Madyan, Y., Welzel, G., & Giordano, F. A. (2012) · Strahlentherapie und Onkologie · doi:10.1007/s00066-012-0151-y · Cited by 1
Guo, L., Song, H., Mao, J., & Tang, Y. (2013) · The Indian Journal of Pediatrics · doi:10.1007/s12098-013-1064-1 · Cited by 1
Treatment related myeloid malignancies in childhood
van den Berg, H. (2014) · Hematology and Leukemia · doi:10.7243/2052-434x-2-3 · Cited by 1
Heredia, F. F., Sousa, J., Magalhães, S. M. M., & Pinheiro, R. (2010) · Leukemia Research · doi:10.1016/j.leukres.2010.07.008 · Cited by 1
Therapy-related leukemia cutis with histopathologic changes resembling xanthogranuloma
Hsiao, P., Lin, J., & Wu, Y. (2011) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2010.04.028 · Cited by 1
Secondary hematological malignancies following breast cancer treatment
Bayraktar, S., & Escalón, M. P. (2010) · Oncology Reviews · doi:10.1007/s12156-010-0037-0 · Cited by 1
Szotkowski, T., Jarošová, M., Zimmermannová, O., Meyer, C., Marschalek, R., Zuna, J., Hubáček, J., & Indrák, K. (2015) · Cancer Genetics · doi:10.1016/j.cancergen.2015.09.004 · Cited by 1
Parekh, V., & Peker, D. (2015) · Leukemia & lymphoma/Leukemia and lymphoma · doi:10.3109/10428194.2015.1083564 · Cited by 1
Nonhematologic Complications of Systemic Treatment of Cancer in the Older-Aged Person
Balducci, L. (2012) · Elsevier eBooks · doi:10.1016/b978-1-4377-1398-5.10014-1 · Cited by 1
Felix, C. A. (2012) · Cambridge University Press eBooks · doi:10.1017/cbo9780511977633.032 · Cited by 1
Association of systemic lupus erythematosus and acute myeloid leukemia: A case report
Randrianarisoa, R. M. F., Andrianiaina, A. M., Sendrasoa, F. A., Ramily, S. L., Razafimaharo, T. I., Ratovonjanahary, V. T., Ramarozatovo, L. S., & Rapelanoro, F. R. (2023) · Medicine Case Reports and Study Protocols · doi:10.1097/md9.0000000000000279 · Cited by 1
Perez, M., Barrionuevo-Villacis, V. M., Arias, C., & Baehring, J. M. (2024) · Cureus · doi:10.7759/cureus.61540 · Cited by 1
Comparative Characteristics of Abnormal Karyotypes in Secondary Acute Leukemia
Andreieva, S. V., Korets, K. V., Tsyapka, O. M., & Skorokhod, I. M. (2024) · Cytology and Genetics · doi:10.3103/s0095452724040029 · Cited by 1
Subsequent Malignant Neoplasms in Childhood Cancer Survivors
Becktell, K., Cotchett, K. R., Volmy, R., & Phelan, R. (2025) · Hematology/Oncology Clinics of North America · doi:10.1016/j.hoc.2026.02.002 · Cited by 1
Two cases of acute lymphoblastic leukaemia following acute myeloid leukaemia
Chevallier, P., Al‐Nawakil, C., Vigouroux, S., Talmant, P., Harousseau, J., & Garand, R. (2008) · Leukemia Research · doi:10.1016/j.leukres.2007.11.014 · Cited by 1
Nash, A. T., & Hambleton, H. (2022) · InnovAiT Education and inspiration for general practice · doi:10.1177/17557380211065056 · Cited by 1
Response of the Bone Marrow Stem Cells and the Microenvironment to Stress
Uçkan, D., & Muratoğlu, B. (2022) · Springer eBooks · doi:10.1007/978-981-16-6016-0_22-1 · Cited by 1
Leukemic Stem Cell-targeting Auger Electron Radioimmunotherapeutic Agent for Acute Myeloid Leukemia
Bergstrom, D. (2015) · TSpace (University of Toronto) · Cited by 1
Galy, A. S. D., Michonneau, D., & Socié, G. (2021) · Wiley eBooks · doi:10.1002/9781119612780.ch12 · Cited by 1
Therapy-related acute myeloid leukemia in autoimmune diseases: caveats and pitfalls
da Silva, R. L. (2015) · International Journal of Clinical Pharmacy · doi:10.1007/s11096-015-0173-5
Hematologic malignancies following external beam radiation therapy for localized prostate cancer
Ojha, R. P. (2010) · Digital Commons @ UNT Health Science Center
Integrated Genomics Of Susceptiblity To Therapy-Related Leukemia
Cahan, P. (2009) · Open Scholarship Institutional Repository (Washington University in St. Louis) · doi:10.7936/k7zg6q7v
Studies of anemia in the myelodysplastic syndromes
Jädersten, M. (2008) · Figshare
The Genetic Basis of Susceptibility to Therapy-related Leukemia in Mice
Janke, M. R. (2014) · Open Scholarship Institutional Repository (Washington University in St. Louis) · doi:10.7936/k75d8pvf
Melloni, G., Muriana, P., Sestini, S., Bandiera, A., Carretta, A., Ciriaco, P. P., Calori, G., Muriana, G., & Zannini, P. (2012) · European Journal of Surgical Oncology · doi:10.1016/j.ejso.2012.05.003
Al-Tahou, K., Jamil, S., Mody, R. J., Knaus, A., Micale, M. A., & Huang, J. Z. (2012) · Cancer Genetics · doi:10.1016/j.cancergen.2012.06.004
Two Secondary Acute Lymphoblastic Leukemia Cases Developed After Cancer Treatment: Case Report
Ali Hakan, K. A. Y. A., KÜBRA, T., Bozdağ, S. C., Tekgündüz, E., & Altuntaş, F. (2015) · Turkiye Klinikleri Journal of Case Reports · doi:10.5336/caserep.2013-37455
Vega-Ruiz, A., O'Brien, S. M., Cortes, J. E., Kebriaei, P., Thomas, D. A., Kantarjian, H. M., & Ravandi, F. (2008) · Leukemia Research · doi:10.1016/j.leukres.2008.02.001
Remacha, A. F., Badell, I., Pujol‐Moix, N., Sánchez, J. H. P., & Muñiz‐Díaz, E. (2009)
Tevet, M., Dragan, C., Șaguna, C., Barbu, D., & Lupu, A. R. (2013) · Europe PMC (PubMed Central)
Raidelet, L. (2011) · OpenGrey (Institut de l'Information Scientifique et Technique)
Short title: Therapy-related MDS and AML after radioiodine treatment
Schroeder, T. A., Kuendgen, A., Käyser, S., Kröger, N. M., Braulke, F., Platzbecker, U., Klärner, V., Zohren, F., Haase, D. T., Stadler, M., et al. (2011)
Watkins, P. L., & Watkins, J. M. (2013) · PubMed
Metadata
- Authors
- Leone, G., Pagano, L., Ben-Yehuda, D., & Voso, M. T.
- Affiliations
- Università Cattolica del Sacro Cuore (IT)
- Corresponding author
- Leone, G.
- Venue
- Haematologica
- Published
- 2007-10-01
- Volume
- 92
- Issue
- 10
- Pages
- 1389-1398
- ISSN
- 0390-6078 (ISSN-L)
- 1592-8721
- OpenAlex
- W2148305047
- Cited by
- 236
- References
- 73
- Citations by year
- 2026: 9 · 2025: 6 · 2024: 4 · 2023: 9 · 2022: 16 · 2021: 15 · 2020: 2 · 2019: 5 · 2018: 6 · 2017: 8 · 2016: 12 · 2015: 16 · 2014: 15 · 2013: 15 · 2012: 19
- FWCI
- 10.79
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Haematologica (publishedVersion)
- PubMed (publishedVersion)
- Cineca Institutional Research Information System (Tor Vergata University) (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- INFM-OAR (INFN Catania) (submittedVersion, other-oa)
- Topics
- Health Sciences › Medicine › Hematology › Acute Myeloid Leukemia Research
- Health Sciences › Medicine › Epidemiology › Multiple and Secondary Primary Cancers
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Retinoids in leukemia and cellular processes
- Keywords
- therapy-related myelodysplastic syndrome, therapy-related acute myeloid leukemia, secondary malignancies, alkylating agents, topoisomerase II inhibitors, azathioprine, DNA mismatch repair, 11q23 translocation, Hodgkin's disease, non-Hodgkin lymphoma, total body irradiation, autologous stem cell transplantation, granulocyte colony-stimulating factor, acute lymphoblastic leukemia, breast cancer, germ cell tumors, genetic susceptibility, polymorphism
- MeSH terms
- Animals, Disease Susceptibility, DNA, DNA Topoisomerases, Type II, DNA Repair, Humans, Leukemia, Myelodysplastic Syndromes, Polymorphism, Genetic, Radiotherapy, Risk Factors, Incidence, Topoisomerase II Inhibitors, Drug-Related Side Effects and Adverse Reactions
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
