Breakthrough C. parapsilosis and C. guilliermondii blood stream infections in allogeneic hematopoietic stem cell transplant recipients receiving long-term caspofungin therapy
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Since 2004, when caspofungin became available at our institution for empirical treatment of fever, we have been faced with the occurrence of candidemia due to unusual species, i.e. C. parapsilosis and C. guilliermondii , which have been reported to exhibit decreased susceptibility to echinocandins
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Less common species such as C. lusitaniae and C. guilliermondii have also been reported in breakthrough Candida infections.
“Less common species such as C. lusitaniae and C. guilliermondii have also been reported.93”
From Epidemiology of Invasive Candidiasis (2024) · cites this paper as [93]
The paper’s case report (pp. 639–640) documents breakthrough C. guilliermondii bloodstream infection in a patient receiving caspofungin. It reports C. parapsilosis, not C. lusitaniae, as the other unusual species in its cases; the C. lusitaniae part of the claim is unsupported by this source. (LLM, conf=0.90)
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References 8 · Cited by 61
Research works printed but not linked: 3
- Pfaller MA, Boyken L, Hollis RJ, Messer SA, Tendolkar S, Diekema DJ. In vitro susceptibilities of Candida spp. to caspofungin: four years of global surveillance. J Clin Microbiol 2006;44:760-3.
- Arrieta AC, Telles Filho F, Berezin E, Freire A, Diekemann- Berndt H. A randomized, double-blind trial comparing micafungin (MCFG) and liposomal amphotericin B (L- AMB) in pediatric patients with invasive candidiasis (IC) (Abstract). Paper presented at the 46th Interscience Conference on Antimicrobial Agents and Chemotherapy, San Fransisco, 2006:M-1308b.
- Clinical Laboratory Standards institute. Reference method for broth dilution antifungal susceptibility testing of yeasts. Approved standard-2nd edition document M27- A2. 2002. CLSI/NCCLS, Wayne, PA, USA. Citation: Kabbara N, Lacroix C, de Latour RP Socié G, Ghannoum M, Ribaud P. Breakthrough C. parapsilosis and C. guilliermondii blood stream infections in allogeneic hematopoetic stem cell transplant recipients receiving long-term caspofungin therapy. Haematologica 2008 Apr; 93(4):639-640. doi: 10.3324/haematol.11149
- Authors
- Kabbara, N., Lacroix, C., Peffault de Latour, R., Socie, G., Ghannoum, M., & Ribaud, P.
- Affiliations
- Université Paris Diderot (FR)
- Venue
- Haematologica
- Published
- 2008-04-01
- Volume
- 93
- Issue
- 4
- Pages
- 639-640
- ISSN
- 0390-6078 (ISSN-L)
- 1592-8721
- OpenAlex
- W1986828869
- Cited by
- 61
- References
- 8
- Citations by year
- 2025: 2 · 2024: 3 · 2023: 3 · 2022: 3 · 2020: 1 · 2018: 2 · 2017: 6 · 2016: 3 · 2015: 3 · 2014: 6 · 2012: 4
- FWCI
- 5.42
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Haematologica (publishedVersion)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- Case Western Reserve University
- Topics
- Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
- Health Sciences › Medicine › Epidemiology › Fungal Infections and Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Yeasts and Rust Fungi Studies
- Keywords
- Candida parapsilosis, Candida guilliermondii, candidemia, bloodstream infection, allogeneic hematopoietic stem cell transplantation, caspofungin, echinocandin resistance, antifungal therapy, empirical antifungal therapy
- MeSH terms
- Caspofungin, Adolescent, Adult, Anemia, Aplastic, Antifungal Agents, Candida, Candidiasis, Humans, Lymphoma, Non-Hodgkin, Male, Middle Aged, Premedication, Retrospective Studies, Transplantation, Homologous, Fluconazole, Fungemia, Treatment Failure, Hematopoietic Stem Cell Transplantation, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Echinocandins, Lipopeptides
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