Emergence and evolution of TP53 mutations are key features of disease progression in myelodysplastic patients with lower-risk del(5q) treated with lenalidomide
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Most known neosubstrate proteins have been identified through proteomic analyses of different cell lineages.
“Most known neosubstrate proteins have been identified through proteomic analyses of different cell lineages11,15,165,166.”
From Cancer therapies based on targeted protein degradation — lessons learned with lenalidomide (2021) · cites this paper as [165]
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References 15 · Cited by 52
- Authors
- Lodé, L., Ménard, A., Flet, L., Richebourg, S., Loirat, M., Eveillard, M., Le Bris, Y., Godon, C., Theisen, O., Gagez, A.-L., Cartron, G., Commes-Maerten, T., Villemagne, B., Luycx, O., Godmer, P., Pellat-Deceunynck, C., Soussi, T., Béné, M. C., Delaunay, J., & Peterlin, P.
- Affiliations
- Centre National de la Recherche Scientifique (FR)
- Centre Hospitalier Universitaire de Nantes (FR)
- Hôpital du Saint-Sacrement (CA)
- Centre Hospitalier Universitaire de Montpellier (FR)
- Centre Hospitalier Départemental Vendée (FR)
- Centre Hospitalier de Bretagne Sud (FR)
- Centre hospitalier Bretagne Atlantique (FR)
- Inserm (FR)
- ORCID
- Venue
- Haematologica
- Published
- 2017-12-21
- Volume
- 103
- Issue
- 4
- Pages
- e143-e146
- ISSN
- 0390-6078 (ISSN-L)
- 1592-8721
- PMC
- PMC5865441
- OpenAlex
- W2777262489
- Cited by
- 52
- References
- 15
- Citations by year
- 2025: 6 · 2024: 3 · 2023: 13 · 2022: 7 · 2021: 8 · 2020: 7 · 2019: 4 · 2018: 2 · 2017: 1
- FWCI
- 2.95
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- other-oa
- Locations
- Haematologica (publishedVersion, other-oa)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion, other-oa)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Funders
- Institut National Du Cancer
- Topics
- Health Sciences › Medicine › Hematology › Acute Myeloid Leukemia Research
- Health Sciences › Medicine › Oncology › Cancer-related Molecular Pathways
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Retinoids in leukemia and cellular processes
- Keywords
- TP53 mutation, del(5q) syndrome, myelodysplastic syndrome, lenalidomide, disease progression, lower-risk myelodysplastic syndromes
- MeSH terms
- Lenalidomide, Chromosome Deletion, Chromosomes, Human, Pair 5, Female, Humans, Male, Middle Aged, Mutation, Myelodysplastic Syndromes, Prognosis, Tumor Suppressor Protein p53, Disease Progression
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