Excess of Free Fatty Acids as a Cause of Metabolic Dysfunction in Skeletal Muscle

TUMOVA, J.; ANDEL, M.; TRNKA, J.

doi:10.33549/physiolres.932993

Excess of Free Fatty Acids as a Cause of Metabolic Dysfunction in Skeletal Muscle

Obesity is often associated with metabolic impairments in peripheral tissues. Evidence suggests an excess of free fatty acids (FFA) as one factor linking obesity and related pathological conditions and the impact of FFA overload on skeletal muscle metabolism is described herein. Obesity is associ…