Short Chain Fatty Acids (SCFAs)-Mediated Gut Epithelial and Immune Regulation and Its Relevance for Inflammatory Bowel Diseases

Parada Venegas, Daniela; De la Fuente, Marjorie K.; Landskron, Glauben; González, María Julieta; Quera, Rodrigo; Dijkstra, Gerard; Harmsen, Hermie J. M.; Faber, Klaas Nico; Hermoso, Marcela A.

doi:10.3389/fimmu.2019.00277

Short Chain Fatty Acids (SCFAs)-Mediated Gut Epithelial and Immune Regulation and Its Relevance for Inflammatory Bowel Diseases

Ulcerative colitis (UC) and Crohn's disease (CD), collectively known as Inflammatory Bowel Diseases (IBD), are caused by a complex interplay between genetic, immunologic, microbial and environmental factors. Dysbiosis of the gut microbiome is increasingly considered to be causatively related to I…