Accurate Quantification and Characterization of Adeno-Associated Viral Vectors

Cited by (125)

Items 101–125 of 125

1. Phase-Appropriate Potency Assay Development for AAV-Based Gene Therapy Products
   Elaine E. Peters, Roland Pach, Shyamtanu Datta · 2023 · Springer eBooks
2. Bioanalytical Methods to Study Biodistribution and Shedding of AAV ‐Based Gene Therapy Vectors
   Christian Vettermann, Russell K. Soon · 2024 · Wiley eBooks
3. Counting DNA in the Clinic Using Digital PCR
   Carolyn Reifsnyder · 2021 · Inside Precision Medicine
4. A Validatable Droplet Digital Polymerase Chain Reaction Assay for the Detection of Adeno-Associated Viral Vectors in Bioshedding Studies of Tears
   Bryanna Longacre, Amanda Souaysene, Carrie A. Vyhlidal, Matthew R. Pennington · 2023 · Journal of Visualized Experiments
5. JoVE Video Dataset
   Bryanna Longacre, Amanda Souaysene, Carrie A. Vyhlidal, Matthew R. Pennington · 2023
6. JoVE Video Dataset
   2024
7. Development of gp64 Gene based Real-time Quantitative PCR Assay for Rapid and Accurate Determination of Baculovirus Titer
   T. , Rama · 2024 · Journal of animal research
8. An automated and high-throughput approach for enhanced precision of adenoviral titering
   Paolo Bottega, Manlio Fusciello, Firas Hamdan, Jacopo Chiaro, Salvatore Russo, Federica D’Alessio, Mikaela Grönholm, Vincenzo Cerullo · 2025 · Molecular Therapy — Methods & Clinical Development
9. Monitoring full-length recombinant adeno-associated virus genome DNA in large-scale production using automated electrophoresis
   Noriko Hashiba, Yuzhe Yuan, Emi Ito-Kudo, Kyoko Masumi‐Koizumi, Keisuke Yusa, Kazuhisa Uchida · 2025 · Translational and Regulatory Sciences
10. A Highly Precise Method for the Quantitation of rAAV Cellular Uptake by ddPCR
    Albert Kiladjian, Prerana Pathak, Marina S. Feschenko, Svetlana Bergelson, Cullen Mason, Yu Wang · 2025 · Human Gene Therapy
11. An Automated Workflow Leveraging Machine Learning for Physical Titer Determination from Cryo-TEM Images of Adeno-Associated Virus Capsids
    Lilianna C. Gutierrez, Anne Skaja Robinson · 2025 · Chemical & Biomedical Imaging
12. Classification and quantification of full vs. empty adeno-associated virus reference capsids via infrared attenuated total reflection spectroscopy
    Silke Lehner, Robert Stach, Robin Nilson, Stefan Kochanek, Astrid Kritzinger, Harald Sobek, Vjekoslav Kokoric, Boris Mizaikoff · 2026 · Analytical and Bioanalytical Chemistry
13. Murine models of lung cancer as a platform to investigate cell death
    Marta Tonietto, Vanessa Jäger, Kathrin Stefanie Maitz, Bettina Flasch, Andreas Reinisch, Julia Kargl, Michael A. Dengler, Philipp Jakob Jost · 2026 · Methods in cell biology
14. Construct optimization for AAV-mediated human α-syn overexpression, and validation across research settings: Development of a shared tool for the research community
    Joaquín Pardo, Janitha M. Mudannayake, Luis Daniel Bernal-Conde, Ivette M. Sandoval, Ryan B. Dong, Martino Avallone, David J. Marmion, Addison R Gralen, Lauren Waite, Andreas Heuer et al. · 2026 · Journal of Parkinson s Disease
15. Spider Webs as Efficient Passive Samplers for Airborne Fungal eDNA in Forests: A Case Study With Hymenoscyphus fraxineus
    Polona Kogovšek, ̧Nikica Ogris, Maja Ferle, Janko Šet, Barbara Piškur, Tjaša Lokovšek, Denis Kutnjak, Matjaž Gregorič · 2026 · Environmental DNA
16. AviNP-Seq: A Blindspot-Free Single-Molecule Framework for Unmasking AAV Genome Heterogeneity and Determining Packaging Limits
    Guohua Li, Yan Xu, Tong Liu, Xiao-Yu Ma, Meng-ting Hou, Shan-Chen PANG, Jian-Ping Zhang, Tao Cheng, Xiao-Bing Zhang · 2026 · Human Gene Therapy
17. Resolving the Unresolvable: Nanopore Sequencing as a Comprehensive Quality Control Platform for Gene Therapy Vectors
    Yan Xu, Xiao-Bing Zhang, Jian-Ping Zhang · 2026 · Human Gene Therapy
18. AAV vector production in suspension cells using PEI transfection and sodium butyrate with orthogonal assessment of function and quality
    Sujan Ravendran, Simon Fammé, Maya Graham Noer, Thomas Wisbech Skov, Nanna S. Mikkelsen, Jessica Lee Schneller, Sofie Rahbek Dorset, Jonas Holst Wolff, Anaïs Marie Julie Møller, Didde Haslund et al. · 2026 · Molecular Therapy Advances
19. Comparative Transcriptomic Profiling Reveals Differences in Initiation of Antiviral Response in Low rAAV Producing HEK293 Suspension Cells
    Georg Smesnik, Nikolaus Virgolini, Astrid Dürauer, Nicole Borth · 2026 · Biotechnology Journal
20. RNA-TITER—An ADAR-based transcript detection assay for accelerated functional titer assessment of adeno-associated viruses
    Tanja Rothgangl, Nancy V. N. Carullo, Philip Ohland, Sandra Kemptner, Denis Phichith, Gianluigi Lichinchi · 2026 · Molecular Therapy Advances
21. Genetically engineered hypoimmunogenic iPSCs: Strategies and considerations for clinical applications
    Jason K.M. Choi, Akitsu Hotta · 2026 · Regenerative Therapy
22. From molecular correction to functional rescue: delivery, tissue state, and immunobiology as the principal constraints on dystrophin-restoring therapy in Duchenne muscular dystrophy
    Ke Li, Huan Qi, 信瑶瑶, Lun Qin, Yulong Cheng, Xin Yao · 2026 · Frontiers in Pharmacology
23. Prime editing of human hematopoietic stem cells for correction of GATA2 deficiency
    Jonas Holst Wolff, Thomas Wisbech Skov, Sofie Rahbek Dorset, Janni Sjelborg, Sujan Ravendran, Anne Louise Revenfeld, Didde Haslund, Anaïs Marie Julie Møller, Mette Holm, Martin Kristian Thomsen et al. · 2026 · Science Translational Medicine
24. Development and qualification of quantitative assays for detecting process-related nucleic acid impurities in recombinant AAV preparations
    Mojca Janc, David Dobnik · 2026 · Molecular Therapy Advances
25. Efficient and High‐Resolution Separation of Partial, Empty, and Full AAV Capsids by Optimized Iodixanol Density Gradient Ultracentrifugation
    Shan Fang, Jun Wu, Yanfang Shen, Dandan Qi, Zhuoyu Ni, FengHua WANG · 2026 · Biotechnology Journal