Role of TGFβ signaling in the pathogenesis of Alzheimer’s disease

Cites (259)

Items 201–259 of 259

1. Modification of microglia function protects from lesion‐induced neuronal alterations and promotes sprouting in the hippocampus
   Ilker Yasin Eyüpoglu, Ingo Bechmann, Robert Nitsch · 2003 · The FASEB Journal
2. Age-dependent responses of glial cells and leptomeninges during systemic inflammation
   Zhou Wu, Yukie Tokuda, Xin-Wen Zhang, Hiroshi Nakanishi · 2008 · Neurobiology of Disease
3. Pro- and anti-inflammatory cytokines regulate the ERK pathway: Implication of the timing for the activation of microglial cells
   Katherine Saud, Rodrigo Herrera‐Molina, Rommy von Bernhardi M. · 2005 · Neurotoxicity Research
4. Intranasally delivered TGF-β1 enters brain and regulates gene expressions of its receptors in rats
   Yuping Ma, Minmin Ma, Ge Song, Ruibing Guo, Huajun Zhang, William H. Frey, Gelin Xu, Xinfeng Liu · 2007 · Brain Research Bulletin
5. Modulation of human microglia and THP-1 cell toxicity by cytokines endogenous to the nervous system
   Andis Klegeris, Christopher J. Bissonnette, Patrick L. McGeer · 2004 · Neurobiology of Aging
6. Pro-inflammatory conditions promote neuronal damage mediated by Amyloid Precursor Protein and decrease its phagocytosis and degradation by microglial cells in culture
   Rommy von Bernhardi M., Gigliola Ramírez, Rodrigo Toro, Jaime L. Eugenín · 2006 · Neurobiology of Disease
7. In Vivo and In Vitro Effects of an Apolipoprotein E Mimetic Peptide on Amyloid-β Pathology
   Shaila P. Handattu, Candyce E. Monroe, Gaurav Nayyar, Mayakonda N. Palgunachari, Inga Kadish, Thomas van Groen, G.M. Anantharamaiah, David W. Garber · 2013 · Journal of Alzheimer s Disease
8. Neurons modulate oxytocin receptor expression in rat cultured astrocytes: Involvement of TGF‐β and membrane components
   Peggy Mittaud, Gérard Labourdette, Hans H. Zingg, Dominique Guénot · 2001 · Glia
9. Aβ Potentiates Inflammatory Activation of Glial Cells Induced by Scavenger Receptor Ligands and Inflammatory Mediators in Culture
   Paola Murgas, B. Godoy, Rommy von Bernhardi M. · 2012 · Neurotoxicity Research
10. Immunohistochemical Evidence for a Macrophage Scavenger Receptor in Mato Cells and Reactive Microglia of Ischemia and Alzheimer's Disease
    Makoto Honda, Haruhiko Akiyama, Yoshihiko Yamada, Hiromi Kondo, Yoshiki Kawabe, Motohiro Takeya, Kiyoshi Takahashi, Hiroshi Suzuki, Takefumi Doi, Atsushi Sakamoto et al. · 1998 · Biochemical and Biophysical Research Communications
11. Nuclear factor‐κB activation by reactive oxygen species mediates voltage‐gated K+ current enhancement by neurotoxic β‐amyloid peptides in nerve growth factor‐differentiated PC‐12 cells and hippocampal neurones
    Anna Pannaccione, Agnese Secondo, Antonella Scorziello, Gaetano Calı̀, Maurizio Taglialatela, Lucio Annunziato · 2005 · Journal of Neurochemistry
12. Uptake of fibrillar β-amyloid by microglia isolated from MSR-A (type I and type II) knockout mice
    Haeyong Chung, Melanie I. Brazil, Michael C. Irizarry, Bradley T. Hyman, Frederick R. Maxfield · 2001 · Neuroreport
13. SMAD3 expression is regulated by mitogen-activated protein kinase kinase-1 in epithelial and smooth muscle cells
    Kristie R. Ross, Deborah A. Corey, John M. Dunn · 2006 · Cellular Signalling
14. Transforming growth factor beta and soluble endoglin in the healthy senior and in Alzheimer's disease patients
    Božena Jurašková, Ctirad Andrýs, Iva Holmerová, Dagmar Solichová, Dana Hrnčiariková, Hana Vaňková, Tomáš Vašátko, Jan Krejsek · 2010 · The journal of nutrition health & aging
15. P38 Activation Mediates Amyloid-β Cytotoxicity
    Xiongwei Zhu, Matthew Genyeh Mei, Hyoung‐gon Lee, Yang Wang, Jiahuai Han, George L. Perry, Mark A. Smith · 2005 · Neurochemical Research
16. Effect of sesaminol glucosides on β-amyloid-induced PC12 cell death through antioxidant mechanisms
    Sun Young Lee, Tae Youl Ha, Dong Ju Son, Sung Ran Kim, Jin Tae Hong · 2005 · Neuroscience Research
17. Age and Time of Day Influences on the Expression of Transforming Growth Factor-Beta and Phosphorylated SMAD3 in the Mouse Suprachiasmatic and Paraventricular Nuclei
    Amy L. Beynon, Johannes Thome, Andrew N. Coogan · 2009 · NeuroImmunoModulation
18. Transforming Growth Factor β1 Modulates Amyloid β-Induced Glial Activation through the Smad3-Dependent Induction of MAPK Phosphatase-1
    Betsi Flores, Rommy von Bernhardi M. · 2012 · Journal of Alzheimer s Disease
19. Role of the Transforming-Growth-Factor-β1 Gene in Late-Onset Alzheimer’s Disease: Implications for the Treatment
    Paolo Bosco, Raffaele Ferri, Maria Grazia Salluzzo, Sabrina Castellano, Maria Salvina Signorelli, Ferdinando Nicoletti, Santo Di Nuovo, Filippo Drago, Filippo Caraci · 2013 · Current Genomics
20. Transforming Growth Factor-β1 Impairs Endothelin-1-Mediated Contraction of Brain Vessels by Inducing Mitogen-Activated Protein (MAP) Kinase Phosphatase-1 and Inhibiting p38 MAP Kinase
    Xin‐Kang Tong, Édith Hamel · 2007 · Molecular Pharmacology
21. Harnessing Immune Alterations in Neurodegenerative Diseases
    Maria Björkqvist, Edward J. Wild, Sarah J. Tabrizi · 2009 · Neuron
22. Resistance of the dentate gyrus to induced apoptosis during ageing is associated with increases in transforming growth factor-β1 messenger RNA
    Nicole Bye, Malgorzata Zieba, Nigel G. Wreford, Nancy R. Nichols · 2001 · Neuroscience
23. TGF-β inhibits the uptake of modified low density lipoprotein by human macrophages through a Smad-dependent pathway: A dominant role for Smad-2
    Daryn R. Michael, Rebecca C. Salter, Dipak P. Ramji · 2012 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
24. Dysregulation of IFN-γ Signaling Pathways in the Absence of TGF-β1
    Nancy L McCartney-Francis, Sharon M. Wahl · 2002 · The Journal of Immunology
25. Microglial expression of αvβ3 and αvβ5 integrins is regulated by cytokines and the extracellular matrix: β5 Integrin null microglia show no defects in adhesion or MMP‐9 expression on vitronectin
    Richard Milner · 2008 · Glia
26. TGFβ Lengthens the G1 Phase of Stem Cells in Aged Mouse Brain
    Mathieu Daynac, José Ramón Pineda, Alexandra Chicheportiche, Laurent Gauthier, Lise Morizur, François Dominique Boussin, Marc‐André Mouthon · 2014 · Stem Cells
27. Differential effects of overexpression of wild-type and mutant human α-synuclein on MPP+-induced neurotoxicity in PC12 cells
    Jin-Jun Qian, Yanbo Cheng, Yaping Yang, Chengjie Mao, Zheng‐Hong Qin, Kai Li, Chun-Feng Liu · 2008 · Neuroscience Letters
28. Proinflammatory Stimuli are Needed for Induction of Microglial Cell-Mediated AβPP244–C and Aβ-Neurotoxicity in Hippocampal Cultures
    Gigliola Ramírez, Sergio Rey, Rommy von Bernhardi M. · 2008 · Journal of Alzheimer s Disease
29. Scavenger receptor class A ligands induce secretion of IL1β and exert a modulatory effect on the inflammatory activation of astrocytes in culture
    B. Godoy, Paola Murgas, Juan Enrique Tichauer, Rommy von Bernhardi M. · 2012 · Journal of Neuroimmunology
30. Acquisition of Secretion of Transforming Growth Factor-β1 Leads to Autonomous Suppression of Scavenger Receptor Activity in a Monocyte-Macrophage Cell Line, THP-1
    Noriyasu Nishimura, Mariko Harada‐Shiba, Shoji Tajima, Ryo Sugano, Taku Yamamura, Qu Zhi Qiang, Akira Yamamoto · 1998 · Journal of Biological Chemistry
31. Measurement of the W+W− Cross Section in s=7 TeV pp Collisions with ATLAS
    G. Aad, B. Abbott, J. Abdallah et al. · 2011 · Physical Review Letters
32. Atorvastatin prevents age-related and amyloid-β-induced microglial activation by blocking interferon-γ release from natural killer cells in the brain
    Anthony Lyons, Kevin J. Murphy, Rachael M. Clarke, Marina A. Lynch · 2011 · Journal of Neuroinflammation
33. Modulation of interferon‐γ‐induced glial cell activation by transforming growth factor β1: A role for STAT1 and MAPK pathways
    Rodrigo Herrera‐Molina, Betsi Flores, Juan Andres Orellana, Rommy von Bernhardi M. · 2012 · Journal of Neurochemistry
34. Proliferating culture of aged microglia for the study of neurodegenerative diseases
    Rommy von Bernhardi M., Juan Enrique Tichauer, Laura Eugenín-von Bernhardi · 2011 · Journal of Neuroscience Methods
35. The 15-Deoxy-Δ12,14-Prostaglandin J2 Suppresses Monocyte Chemoattractant Protein-1 Expression in IFN-γ-Stimulated Astrocytes through Induction of MAPK Phosphatase-1
    Jee Hoon Lee, Joo Hong Woo, Sang Uk Woo, Kwang Soo Kim, Sang Myun Park, Eun-hye Joe, Ilo Jou · 2008 · The Journal of Immunology
36. Tau hyperphosphorylation affects Smad 2/3 translocation
    Shabnam Baig, Zoë Van Helmond, Seth Love · 2009 · Neuroscience
37. Immunotherapy in Alzheimer's Disease: Where Do We Stand? Where Should We Go?
    Rommy von Bernhardi M. · 2010 · Journal of Alzheimer s Disease
38. Smad3 is required for the survival of proliferative intermediate progenitor cells in the dentate gyrus of adult mice
    Silvia Tapia‐González, Marı́a-Dolores Muñoz, María Isabel Cuartero, Amelia Sánchez‐Capelo · 2013 · Cell Communication and Signaling
39. SR-A ligand and M-CSF dynamically regulate SR-A expression and function in primary macrophages via p38 MAPK activation
    Dejan Miodrag Nikolic, Lindsay E. Cormier, Liqin Du, Steven R. Post · 2011 · BMC Immunology
40. Cyclic GMP/Protein Kinase G Phosphorylation of Smad3 Blocks Transforming Growth Factor-β–Induced Nuclear Smad Translocation
    Iain L. O. Buxton, Dayue Darrel Duan · 2008 · Circulation Research
41. Effect of age on proliferation‐regulating factors in human adult neurogenic regions
    Eryn L. Werry, Shilpa Enjeti, Glenda Margaret Halliday, Perminder Singh Sachdev, Kay L. Double · 2010 · Journal of Neurochemistry
42. Role of Scavenger Receptors in Glia-Mediated Neuroinflammatory Response Associated with Alzheimer’s Disease
    Francisca Cornejo, Rommy von Bernhardi M. · 2013 · Mediators of Inflammation
43. Smad2 isoforms are differentially expressed during mouse brain development and aging
    Uwe Ueberham, Peggy Lange, Elke Ueberham · 2009 · International Journal of Developmental Neuroscience
44. Reduction of β-amyloid-induced neurotoxicity on hippocampal cell cultures by moderate acidosis is mediated by transforming growth factor β
    R. Uribe-San Martín, Rodrigo Herrera‐Molina, Lucía Casariego Olavarría, Galo Ramı́rez, Rommy von Bernhardi M. · 2008 · Neuroscience
45. Pravastatin up-regulates transforming growth factor-β1 in THP-1 human macrophages: effect on scavenger receptor class A expression
    Giovanna Baccante, Gabriella Mincione, Maria Carmela Di Marcantonio, Alessandro Piccirelli, Franco Cuccurullo, Ettore Porreca · 2004 · Biochemical and Biophysical Research Communications
46. Regulation of Class A scavenger receptor-mediated cell adhesion and surface localization by PI3K: identification of a regulatory cytoplasmic motif
    Jill Cholewa, Dejan Miodrag Nikolic, Steven R. Post · 2009 · Journal of Leukocyte Biology
47. Scavenger Receptor A Deficiency Accelerates Cerebrovascular Amyloidosis in an Animal Model
    Veronica Lifshitz, Ronen Weiss, Hilit Levy‐Barazany, Dan Frenkel · 2012 · Journal of Molecular Neuroscience
48. SR-A Regulates the Inflammatory Activation of Astrocytes
    P. Murgas, Francisca Cornejo, G. Merino, R. von Bernhardi · 2013 · Neurotoxicity research
49. Alois Alzheimer and the amyloid debate
    John N. Davis, Jane C. Chisholm · 1999 · Nature
50. TGFβ1 enhances formation of cellular Aβ/apoE deposits in vascular myocytes
    Bozena Mazur‐Kolecka, Janusz Frackowiak, Harry LeVine, Taraneh Haske, Lori M. Evans, Thirasak Sukontasup, Adam A. Golabek · 2002 · Neurobiology of Aging
51. Smad-dependent alterations of PPT cholinergic neurons as a pathophysiological mechanism of age-related sleep-dependent memory impairments
    Olivier George, Á. Párducz, David Dupret, Martine Kharouby, Michel Le Moal, P.V. Piazza, Willy Mayo · 2005 · Neurobiology of Aging
52. Sustained activation of ERK signaling in astrocytes is critical for neuronal injury‐induced monocyte chemoattractant protein‐1 production in rat corticostriatal slice cultures
    Takahiro Katayama, Emi Sakaguchi, Yosuke Komatsu · 2010 · European Journal of Neuroscience
53. Overactivated mitogen-activated protein kinase by anisomycin induces tau hyperphosphorylation.
    Qun Wang, Jia-Yu Zhang, Shi Jie Liu, Hong Lian Li · 2008 · PubMed
54. Transforming growth factor‐β1 primes proliferating adult neural progenitor cells to electrophysiological functionality
    Sabrina Kraus, Bernadette Lehner, Nadine Reichhart, Sébastien Couillard‐Després, Katrin Wagner, Ulrich Bogdahn, Ludwig Aigner, Olaf Strauß · 2013 · Glia
55. Microglial reaction in some CNS nuclei following nerves transection in BALB/c and interferon-γ gene knockout mice
    Yee‐Kong Ng, Voon Wee Yong, Eng‐Ang Ling · 1999 · Neuroscience Letters
56. Deletion of tumor necrosis factor death receptor inhibits amyloid β generation and prevents learning and memory deficits in Alzheimer's mice
    Ping He, Zhenyu Zhong, Kristina Lindholm, Lilian Berning, Wendy Lee, Cynthia Ann Lemere, Matthias Staufenbiel, Rena Li, Yong Shen · 2007 · The Journal of Experimental Medicine
57. Measurement of the Three-jet Mass Cross Section in $p\bar{p}$ Collisions at $\sqrt{s}=1.96$ TeV
    Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States), Z. Hubáček, USDOE · 2010
58. Alois Alzheimer Award
    2000 · Psychiatric Bulletin
59. Untitled work
    MP Mattson · 1999 · 10.1002/(sici)1097-4547(19991001)58:1