The P2X7 Receptor-Interleukin-1 Liaison

Cited by (166)

Items 101–166 of 166

1. P2X4 Receptors Mediate Ca2+ Release from Lysosomes in Response to Stimulation of P2X7 and H1 Histamine Receptors
   Sin Lih Tan, Muruj Barri, Peace Atakpa‐Adaji, Colin W. Taylor, Ewan St. John Smith, Ruth D. Murrell‐Lagnado · 2021 · International Journal of Molecular Sciences
2. Cytokine Storm and its Implication in Coronavirus disease 2019 (COVID-19)
   Chandreyee Datta, Ashish Bhattacharjee · 2020 · Journal of Immunological Sciences
3. Increased Pan-Type, A1-Type, and A2-Type Astrocyte Activation and Upstream Inflammatory Markers Are Induced by the P2X7 Receptor
   Keith E. Campagno, Puttipong Sripinun, Lily Pachanin See, Jiaqi Li, Wennan Lu, Assraa Hassan Jassim, Néstor Más Gómez, Claire H. Mitchell · 2024 · International Journal of Molecular Sciences
4. P2X7 Receptors as a Therapeutic Target in Cerebrovascular Diseases
   Abraham Cisneros-Mejorado, Alberto Pérez‐Samartín, Marı́a Domercq, Rogelio O. Arellano, Miroslav Gottlieb, Friedrich Koch‐Nolte, Carlos Matute · 2020 · Frontiers in Molecular Neuroscience
5. The P2X7-Mediated Mitochondrial ROS as an Emerging Core Target of Tuftsin Nanoparticles in Severe Acute Pancreatitis Therapy via Regulating Mitophagy
   E Wen, Yu Tian, Mingxiao Fang, Yuezhou Zhang, Hongyun Zhao, Zhigang Wang, Liang Zhang, Xingsheng Li · 2025 · ACS Applied Materials & Interfaces
6. Purinergic signaling systems across comparative models of spinal cord injury
   Eva E. Stefanova, Angela L. Scott · 2022 · Neural Regeneration Research
7. The P2X7 purinergic receptor in intervertebral disc degeneration
   Letizia Penolazzi, Letícia Scussel Bergamin, Elisabetta Lambertini, Valentina Vultaggio-Poma, Alba Clara Sarti, Pasquale DE BONIS, Francesco Di Virgilio, Roberta Piva · 2021 · Journal of Cellular Physiology
8. Paper-Based Detection Device for Microenvironment Examination: Measuring Neurotransmitters and Cytokines in the Mice Acupoint
   I-Han Hsiao, Hsien-Yin Liao, Chao‐Min Cheng, Chia-Ming Yen, Yi‐Wen Lin · 2022 · Cells
9. Genetic variation of rs7958311 inP2X7Rgene is associated with the susceptibility and disease activity of ankylosing spondylitis
   Zhipeng Pan, Xu Zhang, Yubo Ma, Shengqian Xu, Zongwen Shuai, Faming Pan, Guoping Sun · 2019 · Postgraduate Medical Journal
10. Cdc42 regulates cytokine expression and trafficking in bronchial epithelial cells
    Rowayna Shouib, Gary Eitzen · 2022 · Frontiers in Immunology
11. Alpha linolenic acid intake alleviates myocardial ischemia/reperfusion injury via the P2X7R/NF-κB signalling pathway
    Shuo Wang, Chaxian Liu, Chengxin Gong, Tao Li, Jiani Zhao, Wen Xiao, Yuanyuan Liu, Shanping Peng, Chaopeng Xiong, Rumeng Wang et al. · 2018 · Journal of Functional Foods
12. E. B. Hershberg Award: Taming Inflammation by Tuning Purinergic Signaling
    Kenneth A. Jacobson · 2025 · Accounts of Chemical Research
13. Anti-inflammatory and analgesic properties of Polyphyllin VI revealed by network pharmacology and RNA sequencing
    Zhenglang Zhang, Tingting Wang, Zhenhui Luo, Muhammad Haris Zaib, Mengqin Yi, Hekun Zeng, Peiyang Li, Dan Tang, Alexei Verkhratsky, Hong Nie · 2023 · Purinergic Signalling
14. 6-Furopyridine Hexamethylene Amiloride Is a Non-Selective P2X7 Receptor Antagonist
    Peter Cuthbertson, Amal Elhage, Dena Al-Rifai, Reece Andrew Sophocleous, Ross J. Turner, Ashraf Aboelela, Hiwa Majed, Richard S. Bujaroski, Iman Jalilian, Michael J. Kelso et al. · 2022 · Biomolecules
15. Purinoreceptor P2X7 in Extracellular ATP-Mediated Inflammation through the Spectrum of Kidney Diseases and Kidney Transplantation
    J. Garcia, Thei Sybe Steenvoorden, Fréderike J. Bemelman, Marc L. Hilhorst, Alessandra Tammaro, Liffert Vogt · 2025 · Journal of the American Society of Nephrology
16. P2X7 purinergic receptor plays a critical role in maintaining T-cell homeostasis and preventing lupus pathogenesis
    Amine Mellouk, Tom Hutteau-Hamel, Julie Legrand, Hanaa Safya, Mohcine Benbijja, Françoise Mercier‐Nomé, Karim Benihoud, Jean Kanellopoulos, Pierre Bobé · 2022 · Frontiers in Immunology
17. Processing of angiocrine alarmin IL-1α in endothelial cells promotes lung and liver fibrosis
    Chunxue Zhang, Jie Ma, Xu Zhang, Dengcheng Zhou, Zhongwei Cao, Lina Qiao, Guo Chen, Liming M Yang, Bi‐Sen Ding · 2024 · International Immunopharmacology
18. Regulation of P2X7 receptor function of neural progenitor cells in the hippocampal subgranular zone by neuronal activity in the dentate gyrus
    Muhammad Tahir Khan, Juan Liu, Jana Nerlich, Yong Tang, Heike Franke, Péter Illés · 2018 · Neuropharmacology
19. Unveiling the Potential of Purinergic Signaling in Schistosomiasis Treatment
    Nathália Ferreira Oliveira, Cláudia Lúcia Martins Silva · 2020 · Current Topics in Medicinal Chemistry
20. Immune Response Studies Based on P2X7 Receptors: A Mini-Review
    Ying Deng, Mengting Zhou, Xingtao Zhao, Xinyan Xue, Li Liao, Jing Wang, Yunxia Li · 2022 · Current Pharmaceutical Design
21. IL-36γ is secreted through an unconventional pathway using the Gasdermin D and P2X7R membrane pores
    Laura D. Manzanares, Claudia Ivonne Gutiérrez-Román, Albertana Jiménez‐Pineda, Felipe Castro-Martínez, Genaro Patiño‐López, Martha Eunice Rodríguez-Arellano, Ricardo Valle‐Rios, Vianney Francisco Ortiz-Navarrete, Oscar Medina Contreras · 2022 · Frontiers in Immunology
22. Purinergic P2X7 receptor antagonist ameliorates intestinal inflammation in postoperative ileus
    Hitomi Kimura, Takako YAMAZAKI, Taiki Mihara, Noriyuki Kaji, Kazuhisa Kishi, Masatoshi Hori · 2022 · Journal of Veterinary Medical Science
23. The FXYD1 protein plays a protective role against pulmonary hypertension and arterial remodeling via redox and inflammatory mechanisms
    Thomas S. Hansen, Keyvan Karimi Galougahi, Owen Tang, Michael Tsang, Marielle Scherrer‐Crosbie, Elena Arystarkhova, Kathleen J. Sweadner, Christina A. Bursill, Kristen J. Bubb, Gemma Alexandra Figtree · 2023 · American Journal of Physiology-Heart and Circulatory Physiology
24. P2X7 receptor knockout mice display less aggressive biting behaviour correlating with increased brain activation in the piriform cortex
    Kristie Leigh Smith, Stephanie M. Todd, Aurélie A. Boucher, Maxwell R. Bennett, Jonathon Carl Arnold · 2019 · Neuroscience Letters
25. Purinergic Signaling Within the Tumor Microenvironment
    Dobrin Draganov, Peter P. Lee · 2020 · Advances in experimental medicine and biology
26. Interleukin-1α links peripheral CaV2.2 channel activation to rapid adaptive increases in heat sensitivity in skin
    Anne-Mary N. Salib, Meredith J. Crane, Sang Hun Lee, Brian J. Wainger, Amanda Mercedes Jamieson, Diane Lipscombe · 2024 · Scientific Reports
27. Peripheral Ca V 2.2 Channels in the Skin Regulate Prolonged Heat Hypersensitivity during Neuroinflammation
    Anne-Mary N. Salib, Meredith J. Crane, Amanda Mercedes Jamieson, Diane Lipscombe · 2024 · eNeuro
28. When beta cells talk back
    Heather C. Denroche, Dominika Nąckiewicz, C. Bruce Verchere · 2017 · Diabetologia
29. P2X7 receptor as a potential therapeutic target for perinatal brain injury associated with preterm birth
    Emily Zucker, Irina D. Burd · 2022 · Experimental Neurology
30. Interleukin-1 in monocyte activation phenotypes in systemic juvenile idiopathic arthritis: Observations from a clinical trial of rilonacept, an interleukin-1 inhibitor
    Yujuan Zhang, Saloni Gupta, Alexandra Ilstad-Minnihan, Sashi Ayyangar, Arielle D. Hay, Virginia Pascual, Norman T. Ilowite, Claudia Macaubas, Elizabeth Mellins · 2018 · Clinical Immunology
31. How is the P2X7 receptor signaling pathway involved in epileptogenesis?
    Caichuan Wei, Miaoying Fu, Haiju Zhang, Baozhen Yao · 2024 · Neurochemistry International
32. P2X7 receptor antagonism suppresses epileptiform‐like activity in an inflammation‐primed human iPSC‐derived neuron model of drug‐resistant epilepsy
    Jaideep Kesavan, Yitao Wang, Klaus Dinkel, Michael Hamacher, Jochen H.M. Prehn, David Clifford Henshall, Tobías Engel · 2025 · British Journal of Pharmacology
33. The functional change of the P2X7R containing the Ala348 to Thr polymorphism is associated with the pathogenesis of gout
    Man-Yun Li, Xuan Fang, Yan Ma, Xian-Yang Pan, Xiaojuan Dai, Xiaomei Li, Xiao-Ling Li, Yiping Wang, Jin‐Hui Tao, Xiang-Pei Li · 2023 · Scientific Reports
34. Neurocognitive outcomes in indonesians living with HIV are influenced by polymorphisms in the gene encoding purinergic P2X receptor 7
    Jessica Gaff, Riwanti Estiasari, Dinda Diafiri, Samuel Halstrom, Peter R. Kamerman, Patricia Price · 2021 · Brain Behavior & Immunity - Health
35. Interleukin-receptor antagonist and tumor necrosis factor inhibitors for the primary and secondary prevention of atherosclerotic cardiovascular diseases
    Arturo José Martí-Carvajal, Juan Bautista De Sanctis, Mark Dayer, Cristina Elena Martí-Amarista, Eduardo Alegría, Diana Monge Martín, Mohamed A. Abd El Aziz, Andrea Correa-Pérez, Susana Nicola, Juan Marcos Parise-Vasco · 2021 · Cochrane Database of Systematic Reviews
36. G2019S LRRK2 Mutation Enhances MPP+-Induced Inflammation of Human Induced Pluripotent Stem Cells-Differentiated Dopaminergic Neurons
    Ying Chen, Qing Yin, Xiao-Yu Cheng, Jin‐Ru Zhang, Hong Jin, Kai Li, Chengjie Mao, Fen Wang, Hong-Zhe Bei, Chun‐Feng Liu · 2022 · Frontiers in Neuroscience
37. Interleukin-receptor antagonist and tumour necrosis factor inhibitors for the primary and secondary prevention of atherosclerotic cardiovascular diseases
    Arturo José Martí-Carvajal, Mario A Gemmato-Valecillos, Diana Monge Martín, Mark Dayer, Eduardo Alegría‐Barrero, Juan Bautista De Sanctis, Juan Marcos Parise-Vasco, Ricardo J Riera Lizardo, Susana Nicola, Cristina Elena Martí-Amarista et al. · 2024 · Cochrane Database of Systematic Reviews
38. Hypercholesterolemia Negatively Regulates P2X7-Induced Cellular Function in CD4+ and CD8+ T-Cell Subsets from B6 Mice Fed a High-Fat Diet
    Tom Hutteau-Hamel, Amine Mellouk, Nicolas Trainel, Anne‐Marie Cassard, Pierre Bobé · 2022 · International Journal of Molecular Sciences
39. Nonenzymatic properties of ureases
    Matheus V. Coste Grahl, Augusto Frantz Uberti, Célia R. Carlini · 2024 · Elsevier eBooks
40. Analgesic effect of cinobufagin is mediated by human-selective P2X7R antagonism governed by distinct extracellular domains
    Ke‐Xin Yu, Min Li, Yuchen Jin, Miao Zhao, Zeliang Wang, Haibo Yu · 2025 · Neuropharmacology
41. VNUT-mediated ATP release suppresses T helper 1 (T H 1) cell differentiation via the P2X7R-JNK-FOXO3a-Eomes signaling cascade
    Bolong Wu, Linlin Sheng, Ziyi Feng, Xiaohu Wang, Ligong Chen · 2025 · Science Advances
42. Purinergic signalling pathway: therapeutic target in ovarian cancer
    Nisha Chandran, Mahalaxmi Iyer, Zothan Siama, Balachandar Vellingiri, Arul Narayanasamy · 2020 · Egyptian Journal of Medical Human Genetics
43. Adenosine Triphosphate, Polymyxin B and B16 Cell-Derived Immunization Induce Anticancer Response
    Carlos Barrera‐Avalos, Javier Mena, Ximena López, Claudio Cappelli, T. Neira-Peña, Mónica Imarai, Ricardo Fernández, Claudia Robles-Planells, Leonel E. Rojo, Luis A. Milla et al. · 2021 · Immunotherapy
44. Abstracts from the 2017 Italian-German Purine Club Meeting
    Ilaria Dettori, Elisabetta Coppi, Irene Fusco, Francesca Cencetti, Lisa Gaviano, Paola Bruni, Vittoria Colotta, Daniela Catarzi, Felicita Pedata, Anna Maria Pugliese · 2017 · Purinergic Signalling
45. Inflammatory Cytokines Facilitate the Sensitivity of P2X7 Receptors Toward Extracellular ATP at Neural Progenitor Cells of the Rodent Hippocampal Subgranular Zone
    Juan Liu, Muhammad Tahir Khan, Yong Tang, Heike Franke, Péter Illés · 2018 · Neuroglia
46. Do Inflammatory Cytokines Mediate the Therapeutic Benefits of Exercise in Depressive Disorders? A Scoping Review of Recent English Literature
    Kimia Asgari, Fatema Abdullatif, Amina Ali · 2021 · Undergraduate Research in Natural and Clinical Science and Technology (URNCST) Journal
47. Targeting the purinergic P2X7 receptor in epilepsy: Cell types matter
    Tobías Engel, Valentina Salari, Meng-Juan Sun, Meghma Mitra · 2026 · Neuropharmacology
48. Mechanisms and Therapeutic Targets of Hypoxia-Mediated Modifications in Glycolysis and Lactylation in Rheumatoid Arthritis
    Niqin Xiao, Heguo Yan, Yujiang Xi, Yundong Xu, Jian Zhang, Zhaofu Li, Zhaohu Xie · 2026 · Cells
49. Purinergic Regulation of Neuroinflammation in Traumatic Brain Injury
    Natalia B. Serebryanaya, Elena E. Fomicheva, Якуцени Павел Павлович · 2022 · Neuroscience and Behavioral Physiology
50. Non-aromatizable androgens modulate the lipopolysaccharide induced expression of the P2X7 receptor in human adipocytes
    Angelo Di Vincenzo, Marnie Granzotto, Marika Crescenzi, Roberto Vettor, Marco Rossato · 2023 · Frontiers in Pharmacology
51. Peripheral voltage-gated calcium channels in skin are essential for transient neurogenic thermal hyperalgesia in mice
    Daniel M DuBreuil, Eduardo Javier López Soto, Daniel Li, Diane Lipscombe · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
52. The Function Changes of the Ala348to Thr Polymorphism in the P2X7R Closely Related to the Onset of Gout
    Man-Yun Li, Xuan Fang, Yan Ma, Xian-Yang Pan, Xiaojuan Dai, Xiaomei Li, Xiaoling Li, Yiping Wang, Jin‐Hui Tao, Xiang-Pei Li · 2022 · Research Square
53. Cell Wall Proteins of Staphylococcus aureus Are Involved in Cross Reactivity with Murine Cytokine Assays
    Mehak Gull, Abida Bano, Numan Javed · 2021 · Saudi Journal of Pathology and Microbiology
54. Corrigendum: Purinergic signaling systems across comparative models of spinal cord injury
    2022 · Neural Regeneration Research
55. Novel Leflunomide Analog, UTLOH-4e, Ameliorates Gouty Arthritis Induced by Monosodium Urate Via NF-κB/NLRP3 Signaling Pathway
    Tianmin Yuan, Shilong Chen, Yifeng Yin, Jiajiu Shaw, Jin Zeng, Li Li, Lei Song, Yiguan Zhang, Zhujun Yin, Junning Zhao · 2023 · Current Pharmaceutical Biotechnology
56. Characterizing in vitro and in vivo expression of bovine interleukin-36 in the response to TLR stimulation and bovine respiratory syncytial virus infection
    TOLULOPE PHILIP BABATUNDE · 2024
57. Role of metabolic state, hemodynamics, and neuromonitoring in cardiac arrest survival and neurological outcome
    Masih A. Rafi, Justin D. Yi, Summer Wong, Crystal Eshraghi, Alexander L. Liu, Sheila Abdolmanafi, Brian Pham, Yama Akbari · 2024 · Elsevier eBooks
58. Deoxynivalenol induces pyroptosis and IL-1β secretion via P2X7R signal in murine RAW264.7 macrophages
    Zihui Qin, Huayue Zhang, Jie Zhang, Tushuai Li, Kamil Kuča, Jiaguo Liu, Wenda Wu · 2025 · Toxicon
59. GY971 mitigates inflammation by reducing neutrophil recruitment in cystic fibrosis Ex Vivo and In Vivo models
    Chiara Tupini, Valeria Capurro, Nicoletta Pedemonte, Caterina Allegretta, Onofrio Laselva, Anna Tamanini, Giovanni Marzaro, Adriana Chilin, Paola Patrignani, Stefania Tacconelli et al. · 2025 · Journal of Cystic Fibrosis
60. The P2X7 Receptor and Its Relation to Neglected Tropical Diseases: Focusing on Chagas Disease
    Caroline de Souza Ferreira Pereira, Robson Xavier Faria · 2026 · Journal of Tropical Medicine
61. Protective Effect of Silymarin Against Paclitaxel‐Induced Cardiotoxicity
    Tuğçe Tutar, Seda Yakut, Adem Kara, Aykut Ulucan, Cüneyt Çağlayan · 2026 · Food Science & Nutrition
62. Probenecid is a dual-acting antiviral/anti-inflammatory therapy for diverse respiratory viruses
    Ralph A. Tripp, Les P. Jones, David E. Martin · 2026 · Frontiers in Pharmacology
63. Panx1 and P2X7R are associated with impaired skeletal health and delayed bone development in early onset of type 1 diabetes
    Zeynep Şeref-Ferlengez, Marcia M. Urban-Maldonado, Aylin Uyar, Zar C. Thent, Angela Tun, Bridget P. Saw, Mitchell B. Schaffler, Sylvia O. Suadicani, Mia M. Thi · 2026 · Frontiers in Endocrinology
64. A putative pharmacodynamic ceiling for topical corticosteroids in atopic dermatitis: a steroid-primed inflammasome and caspase-1–mediated glucocorticoid receptor cleavage
    Seung-Yong Seong · 2026 · Frontiers in Immunology
65. BindingDB Entry 50020223: Design, Synthesis, and Biological Evaluation of Novel P2X7 Receptor Antagonists for the Treatment of Septic Acute Kidney Injury.
    BindingDB · 2024 · UC San Diego
66. Targeting the catalytic and ZnF-UBP domains of HDAC6 differentially controls NLRP3 inflammasome priming and assembly in paclitaxel-induced peripheral neuropathy
    Haoran Ying, Ruizhu Yue, Jin Zhang, Xing Guo, Jinsong Li, Wenyu Mo, Yue Hao · 2026 · Pharmacological Research