In Vitro research Reproducibility: Keeping up High Standards

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Items 101–160 of 160

1. Tackling the reproducibility problem to empower translation of preclinical academic drug discovery: is there an answer?
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3. Selective in vitro Synergistic Evaluation of Probiotic Tolerant morpholinyl- and 4-ethylpiperazinyl-Imidazole-chalcone Derivatives on Gastrointestinal System Pathogens
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6. Comparison of physicochemical properties of water- and alkaline-extracted polysaccharides from Schizophyllum commune and their anti-obesogenic effects in vivo
   Chen Li, Chaomin Yin, Jiangtao Li, Jing Wen, Lihong Fan, Haina Ma, Xiuzhi Fan, Defang Shi, Wei Yu, Jianhui Qiu et al. · 2025 · Food Chemistry
7. In vitro methods for assessing gas production and rumen digestibility: Methodological considerations, advantages, and limitations
   Adan U. Chavez-Solis, Amaury Ábrego-García, Samuel Albores-Moreno, David Hernández‐Sánchez, Alejandra Gabriela Yáñez Vergara, José Luis Escobar-Álvarez, Patricia López-Peréa · 2026 · Journal of Microbiological Methods
8. Yeast-Based Screening of Anti-Viral Molecules
   Vartika Srivastava, Ravinder Kumar, Aijaz Ahmad · 2024 · Microorganisms
9. Key parameters for designing robust 2D and 3D spheroid models for in vitro atherosclerosis research
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10. Caenorhabditis elegans: an elegant model organism for evaluating the neuroprotective and neurotherapeutic potential of nutraceuticals
    Altaf S. Darvesh, Reid E. Barnett, Vanessa A. Fitsanakis · 2021 · Elsevier eBooks
11. Reflecting the human lip in vitro: Cleft lip skin and mucosa keratinocytes keep their identities
    Silvia Rihs, Ludovica Parisi, Anic Lauener, Farah A. Mansour, Isabelle Schnyder, Gabriela Marta Dekany, Giorgio C. La Scala, Christos Katsaros, Martin Degen · 2024 · Oral Diseases
12. Ex vivo comparative investigation of suprachiasmatic nucleus excitotoxic resiliency
    Debalina Acharyya, Joanna M. Cooper, Rebecca A. Prosser · 2023 · F1000Research
13. Mathematical and Computational Modelling of Immune Cell Responses in Cell Migration
    Temitope O. Benson · 2024 · Learning materials in biosciences
14. Creating Physiological Cell Environments In Vitro: Adjusting Cell Culture Media Composition and Oxygen Levels to Investigate Mitochondrial Function and Cancer Metabolism
    Sónia Pinho, Georgina L. Gardner, Ricardo Alva, Jeffrey Alan Stuart, Teresa Cunha‐Oliveira · 2024 · Methods in molecular biology
15. Challenges in the translation of chronic wound therapeutics from bench to bedside
    Mandy Li Ling Tan, Jiah Shin Chin, David Laurence Becker · 2024 · Elsevier eBooks
16. 3D models to study therapy-induced senescence: where do we stand now?
    Zahra Heydari, Alexander S. Malogolovkin, Olga Smirnova, Damir Lyukmanov, Alina Filimonova, Anastasia I. Shpichka, Massoud Vosough, Peter S. Timashev · 2025 · Cytotechnology
17. Traumatic Optic Neuropathy After Head Trauma: Pathophysiology, Interventions, and Evidence From Meta‐Analysis
    Cui Huang, Ying Xu, Xiaosu Wu, Shu Tang · 2025 · ANZ Journal of Surgery
18. Methods and applications of patient-derived organoid models for immune microenvironment and immunotherapy research in multiple cancer types
    Yaya Yu, Yanan Li, Jiao Wang, Yan-juan Zhu, Zexin Zhang, Zhenzhen Xiao, Yadong Chen, Yanchun Qu, Ling Han, Haibo Zhang · 2026 · Experimental Hematology and Oncology
19. Mebendazole impairs the expression and function of enzymes in nucleotide metabolism pathways, leading to Selective Cytotoxicity, Cell Cycle Arrest, and Damage to Cell Morphology in Gastric Cancer
    Emerson Lucena da Silva, Felipe Pantoja Mesquita, Pedro Victor da Rocha Lima, José Hélio de Araújo Filho, Francisco Laio de Oliveira, Ana Beatriz da Lima, Pedro Filho Noronha Souza, Raquel Carvalho Montenegro · 2026 · Chemico-Biological Interactions
20. Recent Developments and Applicability of In Vitro Gut Microbiota Models in Biomedical Research and Digestive Diseases—A Systematic Review
    Ioana-Miruna Balmuș, Gabriel Dăscălescu, Viorica Rarinca, Alin Stelian Ciobica, Elena Toader, Georgiana-Emmanuela Gîlcă-Blanariu, Simona Stefania Juncu, Carol Stanciu, Anca Victorita Trifan · 2026 · Medicina
21. Immortalized Rat Tendon-Derived Stem Cells for Tendon Tissue Engineering
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22. Systematic Reviews and Quality Appraisal ofIn VitroCancer Studies: Investigation of Current Practice
    Michael Bracher, Geoffrey John Pilkington, Karen Pilkington · 2021 · Anticancer Research
23. Evaluating the mouse neural precursor line, SN4741, as a suitable proxy for midbrain dopaminergic neurons
    Rachel J. Boyd, Sarah A. McClymont, Nelson B. Barrientos, Paul W. Hook, William Law, Rebecca J. Rose, Eric L. Waite, Jay K. Rathinavelu, Dimitrios Avramopoulos, Andrew S. McCallion · 2023 · BMC Genomics
24. Exploring the In Vitro Effects of Zingerone on Differentiation and Signalling Pathways in Bone Cell Lines
    Brunhildé De Vos, Anna Margaretha Joubert, Abe E. Kasonga, Trevor Tapiwa Nyakudya · 2024 · Metabolites
25. Determination and validation of design space for mesenchymal stem cell cultivation processes using prediction intervals
    Keita Hirono, Yusuke Hayashi, Isuru Abeykoon Udugama, Mohamed Rami Gaddem, Kenjiro Tanaka, Yuto Takemoto, Ryuji Kato, Masahiro Kino‐oka, Hirokazu Sugiyama · 2025 · Communications Biology
26. Model-free Identification of Phenotype-Relevant Variables From Dose Response Data
    Alan Veliz‐Cuba, David Murrugarra, S. Randal Voss · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
27. Estabelecimento de um modelo de epiderme em 3D proveniente de células imortalizadas a ser utilizado como plataforma de avaliação da toxicidade dérmica induzida por corantes de tinturas capilares
    Camila Alessandra Mini · 2020
28. Therapeutic Molecular Targets of Cancer and Animal Models: Adequacy and Drawbacks
    Lucian Hriţcu, Oana Cioancă · 2022 · Handbook of Animal Models and its Uses in Cancer Research
29. Ex vivo comparative investigation of suprachiasmatic nucleus excitotoxic resiliency
    Debalina Acharyya, Joanna M. Cooper, Rebecca A. Prosser · 2023 · F1000Research
30. Therapeutic Molecular Targets of Cancer and Animal Models: Adequacy and Drawbacks
    Lucian Hriţcu, Oana Cioancă · 2023 · Handbook of Animal Models and its Uses in Cancer Research
31. Exploring associations between the teat apex metagenome and Staphylococcus aureus intramammary infection risk in primiparous cows under organic directives
    Chris J. Dean, F. Peña-Mosca, T. Ray, Thomas Wehri, K. Sharpe, A.M. Antunes, Enrique Doster, L. Fernandes, V. F. Calles, Cathy A. Bauman et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
32. Bioprospecção de metabólitos de leveduras para fins biotecnológicos aplicados à saúde
    Ângela Alves dos Santos, Viviani Tadioto, Anderson Giehl, Stéfany Kell Bressan, Larissa Werlang, Camila Girardi de Oliveira, Mariana da Costa Diniz, Triciane Tornai Pereira, Izabella Thaís Silva, Gislaine Fongaro et al. · 2024 · Instituto de Inteligência em Pesquisa e Consultoria Cientifica Ltda eBooks
33. Tendências Biotecnológicas Sustentáveis para Fins de Saúde Única
    2024 · Instituto de Inteligência em Pesquisa e Consultoria Cientifica Ltda eBooks
34. Characterization of the infectivity of an Indonesian Zika virus strain in mammalian cell lines
    Justus T. O. Sievers, Anom Bowolaksono, R. Tedjo Sasmono · 2024 · Asian Pacific Journal of Tropical Biomedicine
35. Standards of Good Practices for the Conduct of In Vitro Toxicity Studies
    Amanda Ulrey · 2025 · Elsevier eBooks
36. Validation of a μ-volume sample holder for non-destructive and contactless assessment of the mechanical properties in soft biomaterials
    Maria Elena Lombardo, Maud Viallon, Dimitria Bonizol Camasão, Pascale Chevallier, Francesco Copes, Roberto López‐Muñoz, David Gendron, Cédric Schmitt A, Anis Hadj Henni, Diego Mantovani · 2025 · Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials
37. Application of HR CS GF-MAS for Determining the Intracellular Concentration of Fluorinated Drugs and Drug Candidates in Cancer Cells, Using Calcium Monofluoride (CaF) as the Target Molecule
    Hubert Aaron Descher, Peter Eta Enoh · 2025 · International Journal of Advanced Pharmaceutical Sciences and Research
38. Methodological Considerations for Setting Up Human-Relevant In Vitro Nanotoxicology Experiments—A Practical Guide
    Vânia Vilas‐Boas, Emma Arnesdotter, Félix Dias Carvalho, Ernesto Alfaro‐Moreno · 2025 · Springer eBooks
39. Evaluation of sources of variability in a nitric oxide screening assay for engineered nanomaterials
    Tariq Fahmi, Robert Gutierrez, Ana Cecilia Barrios, Tae Joon Cho, John T. Elliott, Sanghamitra Majumdar, Bryant C. Nelson, Aaron C. Johnston‐Peck, Alessandro Tona, Anil K. Patri et al. · 2025 · Nanomedicine Nanotechnology Biology and Medicine
40. Label-Free Adherent Cell Counting Based on Deep Learning
    Zuhua Yu, Qiya Hao, Yuanyuan Sun, Hui Tian · 2025 · International Conference on Advanced Algorithms and Neural Networks (AANN)
41. Additional file 1 of Evaluating the mouse neural precursor line, SN4741, as a suitable proxy for midbrain dopaminergic neurons
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42. First-generation merozoites of caprine Eimeria christenseni are capable to invade and egress primary host endothelial cells in vitro
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43. Unveiling Neuroprotective Potential in Tempeh Peptide Extracts by In Vitro Screening of Anti-Alzheimer’s Compounds
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44. Quantitative modeling reveals sources of variability in transcriptional activation assays
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45. Assay integration for reproducible toxicity testing of particulate matter in a single well: cytotoxicity, oxidative stress, inflammatory response, and mRNA profiling
    Andres Henriquez, Marjolaine Godbout-Cheliak, Alain Filiatreault, Dalibor Breznan, Errol M. Thomson · 2026 · Toxicology in Vitro
46. Experimental Models for Adipose Tissue Transplantation
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47. From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy
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48. Ethical Challenges and Barriers in Animal Experimentation
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49. New insights in tumor-on-a-chip models for studying cancer drug resistance
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50. Galleria mellonella as an invertebrate screening model for biocompatibility and in vivo functionality testing of imaging contrast agents
    Timen Mooren, Birger Tielemans, Agustin Reséndiz-Sharpe, Greetje Vande Velde · 2026 · Alternatives to Laboratory Animals
51. Opportunities and challenges for analytical chemists: organ-on-chip devices as new approach methods (NAMs) for identifying potential toxins
    Evan Huang, Jose A. Nolasco, Sarina J. Jones, Matthew Ryen Lockett · 2026 · The Analyst
52. MicroRNAs and SGLT2 inhibitors in cardiovascular disease: Shared pathways and emerging roles
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53. IncuSense: IoT-Enabled Wireless Long-Term Multiparametric Cell Culture Incubator Monitoring System
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54. Muscle in fat trouble: The rise of IMAT in metabolic and musculoskeletal disease
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55. Beyond Tissue Origin: Rethinking Experimental Model Selection in Rotator Cuff Research
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56. Circular RNAs at the crossroads of oxidative stress: novel targets for precision therapeutics
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57. From literature to lab: LLM-powered catalyst synthesis protocol generation
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58. Cell Cultures as a Platform for Optical Diagnostics and Toxicological Analysis: Cancer Predictors and Cytotoxicity of Organic Compounds
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59. Integration of In Vitro Exposure Data into the ECOTOXicology Knowledgebase and Application to Adverse Outcome Pathway Development
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60. Optimization of antibiotic and antimycotic compositions for the eradication of microorganisms from cell cultures
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