Mitochondrial (Dys)function and Insulin Resistance: From Pathophysiological Molecular Mechanisms to the Impact of Diet

Sergi, Domenico, Naumovski, Nenad, Heilbronn, Leonie Kaye, Abeywardena, Mahinda, O’Callaghan, Nathan, Lionetti, Lillà, Luscombe-Marsh, Natalie·2019·Frontiers in Physiology

Cited by (344)

Items 101–200 of 344

  1. Shared risk and protective factors between Alzheimer's disease and ischemic stroke: a population-based longitudinal study
    Wang, Rui, Qiu, Chengxuan, Dintica, Christina S., Shang, Ying, Calderón Larrañaga, Amaia, Wang, Hui‐Xin, Xu, Weili · 2021 · Alzheimer's & Dementia
  2. Plant-based Diets and Phytochemicals in the Management of Diabetes Mellitus and Prevention of its Complications: A Review
    Ansari, Prawej, Khan, Joyeeta Tahseen, Choudhary, Suraiya, Reberio, Alexa Depheny, Kumar, Sandeep, Seidel, Veronique, Abdel-Wahab, Yasser H. A., Flatt, Peter R. · 2024
  3. Ceramides as Emerging Players in Cardiovascular Disease: Focus on Their Pathogenetic Effects and Regulation by Diet
    Riccardo Spaggiari, Sharon Angelini, Alessandra Di Vincenzo, Gerarda Scaglione, Sara Morrone, Veronica Finello, Sofia Fagioli, Fabiola Castaldo, Juana María Sanz, Domenico Sergi et al. · 2024 · Advances in Nutrition
  4. Inter-Organelle Crosstalk in Oxidative Distress: A Unified TRPM2-NOX2 Mediated Vicious Cycle Involving Ca2+, Zn2+, and ROS Amplification
    Esra Elhashmi Shitaw, Maali AlAhmad, Asipu Sivaprasadarao · 2025 · Antioxidants
  5. Human induced pluripotent stem cell-derived cardiomyocytes reveal abnormal TGFβ signaling in type 2 diabetes mellitus
    Ling Fung Paul Tang, Hongkun Wang, Bing Dai, Xiaochen Wang, Danni Zhou, Jiaxi Shen, Fengfeng Guo, Jue Wang, Jing‐Jun Zhou, Hao Wang et al. · 2020 · Journal of Molecular and Cellular Cardiology
  6. Acute exercise increases the contact between lipid droplets and mitochondria independently of obesity and type 2 diabetes
    Martin Eisemann de Almeida, Niels Ørtenblad, Maria Houborg Petersen, A Schjerning, Emil Kleis Wentorf, Kurt Jensen, Kurt Højlund, Joachim Nielsen · 2023 · The Journal of Physiology
  7. Burn injury insulin resistance and central nervous system complications: A review
    Jorge Berlanga‐Acosta, Yssel Mendoza‐Marí, Nadia Rodríguez-Rodríguez, Diana García del Barco Herrera, Ariana García Ojalvo, Maday Fernández‐Mayola, Gerardo E Guillén, Pedro Antonio Valdes-Sosa · 2020 · Burns Open
  8. High-Fish Oil and High-Lard Diets Differently Affect Testicular Antioxidant Defense and Mitochondrial Fusion/Fission Balance in Male Wistar Rats: Potential Protective Effect of ω3 Polyunsaturated Fatty Acids Targeting Mitochondria Dynamics
    Vincenzo Migliaccio, Raffaella Sica, Ilaria Di Gregorio, Rosalba Putti, Lillà Lionetti · 2019 · International Journal of Molecular Sciences
  9. Energy transfer between the mitochondrial network and lipid droplets in insulin resistant skeletal muscle
    Hailey A. Parry, Brian C. Glancy · 2021 · Current Opinion in Physiology
  10. The Role of L-Carnitine in Kidney Disease and Related Metabolic Dysfunctions
    Tim Ulinski, Maria Cirulli, Ashraf Virmani · 2023 · Kidney and Dialysis
  11. Insights into the Role of Plasmatic and Exosomal microRNAs in Oxidative Stress-Related Metabolic Diseases
    Ayauly Duisenbek, Gabriela del Carmen López-Armas, Miguel Pérez, Maria D. Perez, José Miguel Aguilar Benítez, Víctor Roger Pereira Pérez, Juan Gorts Ortega, Arailym Yessenbekova, Н.Т. Аблайханова, Germaine Escames et al. · 2023 · Antioxidants
  12. A Narrative Review of Non-Pharmacological Strategies for Managing Sarcopenia in Older Adults with Cardiovascular and Metabolic Diseases
    Theocharis Ispoglou, Oliver J. Wilson, Deaglan McCullough, Luke Aldrich, Panagiotis P. Ferentinos, Gemma K. Lyall, Antonios Stavropoulos‐Kalinoglou, Lauren C. Duckworth, Meghan A. Brown, Louise Sutton et al. · 2023 · Biology
  13. Polysaccharides from natural resource: ameliorate type 2 diabetes mellitus via regulation of oxidative stress network
    Liying He, Yong Li, Shuqi Niu, Jing Bai, Sijing Liu, Jinlin Guo · 2023 · Frontiers in Pharmacology
  14. Prediabetes-Associated Changes in Skeletal Muscle Function and Their Possible Links with Diabetes: A Literature Review
    Mandlakazi Dlamini, Andile Khathi · 2023 · International Journal of Molecular Sciences
  15. Impact of diet and exercise on mitochondrial quality and mitophagy in Alzheimer's disease
    Jangampalli Adi Pradeepkiran, Md. Ariful Islam, Ujala Sehar, Arubala P. Reddy, Murali Vijayan, P. Hemachandra Reddy · 2025 · Ageing Research Reviews
  16. Blueberry Counteracts Prediabetes in a Hypercaloric Diet-Induced Rat Model and Rescues Hepatic Mitochondrial Bioenergetics
    Sara Nunes, Sofia Viana, Inês Preguiça, André Alves, Rosa Fernandes, João Soeiro Teodoro, Patrícia Matos, Artur Figueirinha, Lı́gia Salgueiro, Alexandra André et al. · 2021 · Nutrients
  17. Ginger Root Extract Improves GI Health in Diabetic Rats by Improving Intestinal Integrity and Mitochondrial Function
    Rui Wang, Julianna Maria Santos, Jannette M. Dufour, Emily R. Stephens, Jonathan M. Miranda, Rachel L. Washburn, Taylor Hibler, Gurvinder Kaur, Dingbo Lin, Chwan‐Li Shen · 2022 · Nutrients
  18. Glutamine Ameliorates Liver Steatosis via Regulation of Glycolipid Metabolism and Gut Microbiota in High-Fat Diet-Induced Obese Mice
    Xinbo Zhou, Junjie Zhang, Yutong Sun, Jian Shen, Bo Sun, Qingquan Ma · 2023 · Journal of Agricultural and Food Chemistry
  19. L-glutamine ameliorates adipose-hepatic dysmetabolism in OC-treated female rats
    Kehinde Samuel Olaniyi, Lawrence A. Olatunji · 2020 · Journal of Endocrinology
  20. Antimycin A-induced mitochondrial dysfunction is consistent with impaired insulin signaling in cultured skeletal muscle cells
    Sithandiwe Eunice Mazibuko-Mbeje, Sinenhlanhla X. H. Mthembu, Phiwayinkosi Vusi Dludla, Evelyn Madoroba, Nireshni Chellan, Abidemi Paul Kappo, Christo J. F. Muller · 2021 · Toxicology in Vitro
  21. Dose- and Time-Dependent Effects of Oleate on Mitochondrial Fusion/Fission Proteins and Cell Viability in HepG2 Cells: Comparison with Palmitate Effects
    Isy Faria de Sousa, Vincenzo Migliaccio, Marilena Lepretti, Gaetana Paolella, Ilaria Di Gregorio, Ivana Caputo, Eliane Beraldi Ribeiro, Lillà Lionetti · 2021 · International Journal of Molecular Sciences
  22. Functionalized and Nonfunctionalized Nanosystems for Mitochondrial Drug Delivery with Metallic Nanoparticles
    Shashi Kiran Misra, Jessica M. Rosenholm, Kamla Pathak · 2023 · Molecules
  23. Nutraceuticals as Potential Targets for the Development of a Functional Beverage for Improving Sleep Quality
    Amanda Bulman, Nathan Martin D'Cunha, Wolfgang Marx, Andrew J. McKune, Rati Jani, Nenad Naumovski · 2021 · Beverages
  24. Gender Differences in Body Composition in Pre-Frail Older Adults With Diabetes Mellitus
    Reshma Aziz Merchant, John Tshon Yit Soong, John Edward Morley · 2022 · Frontiers in Endocrinology
  25. Mitochondrial transfer restores impaired liver functions by AMPK/ mTOR/PI3K-AKT pathways in metabolic syndrome
    Swati Paliwal, Smita Jain, Pallavi Mudgal, Kanika Verma, Sarvesh Paliwal, Swapnil K. Sharma · 2023 · Life Sciences
  26. Prickly Pear Cacti (Opuntia spp.) Cladodes as a Functional Ingredient for Hyperglycemia Management: A Brief Narrative Review
    Rao Raahim Kashif, Nathan Martin D'Cunha, Duane Daniel Mellor, Natalie I. Alexopoulos, Domenico Sergi, Nenad Naumovski · 2022 · Medicina
  27. Is insulin resistance tissue-dependent and substrate-specific? The role of white adipose tissue and skeletal muscle
    Diana Calderón-DuPont, Iván Torre-Villalvazo, Andrea Díaz‐Villaseñor · 2022 · Biochimie
  28. Cocoa Flavanol Supplementation and the Effect on Insulin Resistance in Females Who Are Overweight or Obese: A Randomized, Placebo-Controlled Trial
    Elizabeth J. Simpson, Buddhike Mendis, Mandy V. Dunlop, Hagen Schroeter, Catherine L. Kwik-Uribe, Ian Andrew Macdonald · 2023 · Nutrients
  29. Therapeutic Potential of Selenium Nanoparticles on Letrozole-Induced Polycystic Ovarian Syndrome in Female Wistar Rats
    Maisra Azhar Butt, Hafiz Muhammad Shafique, Mahjabeen Mustafa, Nurain Baig Moghul, Anum Munir, Urwah Shamas, Sobia Tabassum, Mubin Mustafa Kiyani · 2023 · Biological Trace Element Research
  30. Blocking AMPKαS496 phosphorylation improves mitochondrial dynamics and hyperglycemia in aging and obesity
    Alexia Pearah, Balamurugan Ramatchandirin, Ting Liu, Risa M. Wolf, Arisa Ikeda, Sally Radovick, Hiromi Sesaki, Fredric Edward Wondisford, Brian P O'Rourke, Ling He · 2023 · Cell chemical biology
  31. Review: Insulin resistance and mitochondrial dysfunction following severe burn injury
    Jorge Berlanga‐Acosta, Ileidys Iglesias-Marichal, Nadia Rodríguez-Rodríguez, Yssel Mendoza‐Marí, Ariana García Ojalvo, Maday Fernández‐Mayola, Raymond John Playford · 2020 · Peptides
  32. The Inhibition of Metabolic Inflammation by EPA Is Associated with Enhanced Mitochondrial Fusion and Insulin Signaling in Human Primary Myotubes
    Domenico Sergi, Natalie D. Luscombe‐Marsh, Leonie Kaye Heilbronn, Mark A. Birch‐Machin, Nenad Naumovski, Lillà Lionetti, Christopher G. Proud, Mahinda Yapa Abeywardena, Nathan J. O’Callaghan · 2020 · Journal of Nutrition
  33. Passive heat stress induces mitochondrial adaptations in skeletal muscle
    Erik D. Marchant, W. Bradley Nelson, Robert D. Hyldahl, Jayson R. Gifford, Chad R. Hancock · 2023 · International Journal of Hyperthermia
  34. Strength training improves insulin resistance and differently affects mitochondria in skeletal muscle and visceral adipose tissue in high-fat fed mice
    Juliana Sales Rodrigues Costa, Graciene Fernandes Araújo Campos Fonseca, Natielle Cecília dos Santos Ottone, Patrick Almeida Silva, Romulo Fernandes Antonaccio, Gabriela Silva, Maíra da Silva Almeida Rocha, Cândido Celso Coimbra, Elizabethe Adriana Esteves, Zachary Aaron Mang et al. · 2021 · Life Sciences
  35. Intramuscular Injection of miR-1 Reduces Insulin Resistance in Obese Mice
    Alice Cristina Rodrigues, Alexandre Roveratti Spagnol, Flávia de Toledo Frias, Mariana de Mendonça, Hygor N. Araújo, Dimitrius Santiago P.S.F. Guimarães, William Jose Silva, Anaysa Paola Bolin, Gilson Masahiro Murata, Leonardo R. Silveira · 2021 · Frontiers in Physiology
  36. Protective effects of extra virgin olive oil and exercise training on rat skeletal muscle against high-fat diet feeding
    Dongwook Yeo, Tianou Zhang, Tao Liu, Yuzi Zhang, Chounghun Kang, Li Li Ji · 2021 · The Journal of Nutritional Biochemistry
  37. Activation of PGC ‐1α via isoliquiritigenin‐induced downregulation of miR ‐138‐5p alleviates nonalcoholic fatty liver disease
    Lu Wang, Xiaohui Wang, Lina Kong, Yingying Li, Kai Huang, Jingjing Wu, Changyuan Wang, Huijun Sun, Pengyuan Sun, Jiangning Gu et al. · 2022 · Phytotherapy Research
  38. Decreased expression of mitochondrial aminoacyl-tRNA synthetases causes downregulation of OXPHOS subunits in type 2 diabetic muscle
    Iliana López‐Soldado, Adrián Gabriel Torres, Raúl Ventura, Inma Martínez-Ruíz, Angels Díaz‐Ramos, Evarist Planet, Diane Cooper, Agnieszka Pazderska, Krzysztof Wanic, Declan O’Hanlon et al. · 2023 · Redox Biology
  39. MitoNEET prevents iron overload‐induced insulin resistance in H9c2 cells through regulation of mitochondrial iron
    Eddie Tam, Hye Kyoung Sung, Gary Sweeney · 2023 · Journal of Cellular Physiology
  40. Acrolein induces mitochondrial dysfunction and insulin resistance in muscle and adipose tissues in vitro and in vivo.
    Jia-Yu Jhuo, Zhen-Jie Tong, Pei-Hsuan Ku, Hsiao-Wei Cheng, Hsiang‐Tsui Wang · 2023 · Environmental Pollution
  41. High-intensity interval training reduced oxidative stress and apoptosis in the hippocampus of male rats with type 2 diabetes: The role of the PGC1α-Keap1-Nrf2 signaling pathway.
    Narjes Ebrahimnezhad, Shila Nayebifar, Zahra Soltani, Kayvan Khoramipour · 2023 · PubMed Central
  42. Eucaloric diets enriched in palm olein, cocoa butter, and soybean oil did not differentially affect liver fat concentration in healthy participants: a 16-week randomized controlled trial.
    Stonehouse, Welma, Sergi, Domenico, Benassi-Evans, Bianca, James-Martin, Genevieve, Johnson, Nathan, Thompson, Campbell H, Abeywardena, Mahinda · 2021 · The American Journal of Clinical Nutrition
  43. Exercise Preconditioning Blunts Early Atrogenes Expression and Atrophy in Gastrocnemius Muscle of Hindlimb Unloaded Mice
    Lorenza Brocca, Maira Rossi, Monica Canepari, Roberto Bottinelli, Maria Antonietta Pellegrino · 2021 · International Journal of Molecular Sciences
  44. Biomedical aspects of beta-glucan on glucose metabolism and its role on primary gene PIK3R1
    Shreya Chakraborty, Vijayarangan Devi Rajeswari · 2022 · Journal of Functional Foods
  45. Inhibition of mitochondrial fission and iNOS in the dorsal vagal complex protects from overeating and weight gain
    Bianca Patel, Lauryn E. New, Joanne C. Griffiths, Jim Deuchars, B Filippi · 2020 · Molecular Metabolism
  46. Assessment of the antidiabetic potential of extract and novel phytoniosomes formulation of Tradescantia pallida leaves in the alloxan‐induced diabetic mouse model
    Fariha Imtiaz, Muhammad Fajrul Islam, Hamid Saeed · 2023 · The FASEB Journal
  47. Super Fruit Amla (Emblica officinalis, Gaertn) in Diabetes Management and Ensuing Complications: A Concise Review
    Muhammed A. Majeed, Narayanan K. Narayanan, Lakshmi Mundkur, Priji Prakasan, Kalyanam Nagabhushanam · 2023 · Nutraceuticals
  48. Long-term programming of skeletal muscle and liver lipid and energy metabolism by resveratrol supplementation to suckling mice
    Alba Serrano, Joan Ribot, Andreu Palou, Maria Luisa Bonet · 2021 · The Journal of Nutritional Biochemistry
  49. Precision nutrition for targeting pathophysiology of cardiometabolic phenotypes
    Chris E. Shannon, Méabh B. Ní Chathail, Sinéad M. Mullin, Andrew Meehan, Fiona C. McGillicuddy, Helen M. Roche · 2023 · Reviews in Endocrine and Metabolic Disorders
  50. Toward Ameliorating Insulin Resistance: Targeting a Novel PAK1 Signaling Pathway Required for Skeletal Muscle Mitochondrial Function
    Rekha Balakrishnan, Pablo A. Garcia, Rajakrishnan Veluthakal, Janice M. Huss, Joseph M. Hoolachan, Debbie C. Thurmond · 2023 · Antioxidants
  51. Resveratrol: biology, metabolism, and detrimental role on the tumor microenvironment of colorectal cancer
    Begum Dariya, Bala Prabhakar Girish, Neha Merchant, Mundla Srilatha, Ganji Purnachandra Nagaraju · 2023 · Nutrition Reviews
  52. MitoNEET Provides Cardioprotection via Reducing Oxidative Damage and Conserving Mitochondrial Function
    Eddie Tam, Gary Sweeney · 2023 · International Journal of Molecular Sciences
  53. The complex interplay between oxinflammation, mitochondrial dysfunction and lipotoxicity: Focus on their role in the pathogenesis of skeletal muscle insulin resistance and modulation by dietary fatty acids
    Angelina Passaro, Juana María Sanz, Nenad Naumovski, Domenico Sergi · 2024 · Advances in Redox Research
  54. The paradox of fatty-acid β-oxidation in muscle insulin resistance: Metabolic control and muscle heterogeneity
    Marcel A. Vieira‐Lara, Barbara M. Bakker · 2024 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  55. Peanut Shell Extract Improves Mitochondrial Function in db/db Mice via Suppression of Oxidative Stress and Inflammation
    Hemalata Deshmukh, Julianna Maria Santos, Matthew Bender, Jannette M. Dufour, Jacob Lovett, Chwan‐Li Shen · 2024 · Nutrients
  56. Artificial mitochondrial transplantation (AMT) reverses aging of mesenchymal stromal cells and improves their immunomodulatory properties in LPS-induced synoviocytes inflammation
    Lynda Bourebaba, Nabila Bourebaba, Larry D. Galuppo, Krzysztof Marycz · 2024 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  57. Interaction among inflammasome, autophagy and non-coding RNAs: new horizons for drug
    Qinqin Pu, Ping Lin, Zhihan Wang, Pan Gao, Shugang Qin, Luqing Cui, Min Wu · 2019 · Precision Clinical Medicine
  58. Age and sex as confounding factors in the relationship between cardiac mitochondrial function and type 2 diabetes in the Nile Grass rat
    Jillian Schneider, Woo Hyun Han, Rebecca Matthew, Yves Sauvé, Hélène Lemieux · 2020 · PLoS ONE
  59. Momordica charantia nanoparticles promote mitochondria biogenesis in the pancreas of diabetic-induced rats: gene expression study
    Olusola Olalekan Elekofehinti, Olusola Christianah Ayodele, Opeyemi Iwaloye · 2021 · Egyptian Journal of Medical Human Genetics
  60. Genomic and physiological resilience in extreme environments are associated with a secure attachment style
    Viviana Caputo, Maria Giuseppina Pacilli, Ivan Arisi, Tommaso Mazza, Rossella Brandi, Alice Traversa, Giampietro Casasanta, Edoardo Pisa, Michele Sonnessa, Beth Healey et al. · 2020 · Translational Psychiatry
  61. A review on manganese and its effect on health and distribution in selected African countries
    Irene Ebosereme Ainyanbhor, Great Iruoghene Edo, Patrick Othuke Akpoghelie, Joseph Oghenewogaga Owheruo, Tayser Sumer Gaaz, Emad A. Yousif, Endurance Fegor Isoje, Ufuoma Augustina Igbuku, Rapheal Ajiri Opiti, Arthur Efeoghene Athan Essaghah et al. · 2025 · Journal of Trace Elements in Medicine and Biology
  62. The Dual Role of Metformin: Repurposing an Antidiabetic Drug for Cancer Therapy
    Flávia Barbosa, Andrea Cunha, Joana Barbosa, Juliana Faria, Odília Queirós · 2025 · Applied Sciences
  63. Serum Uric Acid as a Mediator of Insulin Resistance: Molecular Mechanisms and Metabolic Pathways
    Nurshad Ali · 2026 · Endocrinology Diabetes & Metabolism
  64. Microalgae as a Nutraceutical Tool to Antagonize the Impairment of Redox Status Induced by SNPs: Implications on Insulin Resistance
    Mattia Melloni, Domenico Sergi, Carolina Simioni, Angelina Passaro, Luca Maria Neri · 2023 · Biology
  65. GDF-15 and mtDNA Deletions Are Useful Biomarkers of Mitochondrial Dysfunction in Insulin Resistance and PCOS
    Vera Várhegyi, Anna Módos, Domonkos Trager, Dóra Gerszi, Eszter Maria Horvath, Miklós Sipos, Nándor Ács, Mária Judit Molnár, Szabolcs Várbíró, Anikó Gál · 2024 · International Journal of Molecular Sciences
  66. Functional Foods and Nutraceuticals for the Management of Cardiovascular Disease Risk in Postmenopausal Women
    H. Meegaswatte, K. Speer, Andrew J. McKune, N. Naumovski · 2024 · Reviews in cardiovascular medicine
  67. Multi-Tissue DNA Methylation Remodeling at Mitochondrial Quality Control Genes According to Diet in Rat Aging Models
    Patrizia D’Aquila, Francesco De Rango, Francesco Guarasci, Maurizio Mandalà, Andrea Corsonello, Dina Bellizzi, Giuseppe Passarino · 2020 · Nutrients
  68. From Molecular Insights to Clinical Management of Gestational Diabetes Mellitus—A Narrative Review
    Mohamed-Zakaria Assani, Lidia Boldeanu, Maria Magdalena Manolea, Mihail Virgil Boldeanu, Isabela Siloşi, Alexandru-Dan Assani, Constantin-Cristian Văduva, Anda Lorena Dijmărescu · 2025 · International Journal of Molecular Sciences
  69. Hindlimb immobilization induces insulin resistance and elevates mitochondrial ROS production in the hippocampus of female rats
    Nathan R. Kerr, Chandler W. Mossman, Chih‐Hsuan Chou, Josh Bunten, Taylor J. Kelty, Thomas E. Childs, R. Scott Rector, William David Arnold, Laurel A. Grisanti, Xiangwei Du et al. · 2024 · Journal of Applied Physiology
  70. Linoleic Acid, Mitochondria, Gut Microbiome, and Metabolic Health: A Mechanistic Review
    J. Mercola · 2025 · Advances in Redox Research
  71. Atorvastatin impairs liver mitochondrial function in obese Göttingen Minipigs but heart and skeletal muscle are not affected
    Liselotte Bruun Christiansen, Tine Lovsø Dohlmann, Trine Pagh Ludvigsen, Ewa Parfieniuk, Michał Ciborowski, Łukasz Szczerbiński, Adam Jacek Kretowski, Claus Desler, Luca Tiano, Patrick Orlando et al. · 2021 · Scientific Reports
  72. The Effect of Ex Vivo Human Serum from Liver Disease Patients on Cellular Protein Synthesis and Growth
    S. Allen, Alex Peter Seabright, Jonathan Iain Quinlan, Amritpal Dhaliwal, Felicity Rhian Williams, Nicholas H. F. Fine, David J. Hodson, Matthew James Armstrong, A Elsharkaway, Carolyn Anne Greig et al. · 2022 · Cells
  73. Nutraceutical Prevention of Diabetic Complications—Focus on Dicarbonyl and Oxidative Stress
    Mark Frederick McCarty, James J. DiNicolantonio, James Henry O’Keefe · 2022 · Current Issues in Molecular Biology
  74. Randomized nutrient bar supplementation improves exercise-associated changes in plasma metabolome in adolescents and adult family members at cardiometabolic risk
    Michele Mietus‐Snyder, Nisha Narayanan, Ronald M. Krauss, Kirsten Laine-Graves, Joyce C. McCann, Mark K. Shigenaga, Tara H. McHugh, Bruce N. Ames, Jung H. Suh · 2020 · PLoS ONE
  75. Diabetic cardiomyopathy attenuated the protective effect of ischaemic post-conditioning against ischaemia-reperfusion injury in the isolated rat heart model
    Gino A. Kurian, Mahalakshmi Ansari, Priyanka N. Prem · 2020 · Archives of Physiology and Biochemistry
  76. Metabolic Reprogramming Through Polyphenol Networks: A Systems Approach to Metabolic Inflammation and Insulin Resistance
    Shakila Jahan Shimu, Jawad Ul Karim Mahir, Fardin Al Fahad Shakib, Arafath Amin Ridoy, Ratin Al Samir, Nadia Jahan, Md Fahim Hasan, Sadman Sazzad, Shamima Akter, Mohammad Sarif Mohiuddin et al. · 2025 · Medical Sciences
  77. Obesity–An Update on the Basic Pathophysiology and Review of Recent Therapeutic Advances
    Erind Gjermeni, Anna Kirstein, Florentien Kolbig, Michael Kirchhof, Linnaeus Bundalian, Julius L. Katzmann, Ulrich Laufs, Matthias Blüher, Antje Garten, Diana Le Duc · 2021 · Biomolecules
  78. Denervation impacts muscle quality and knee bone mineral density after spinal cord injury
    Ahmad M. Alazzam, Jacob A. Goldsmith, Refka E. Khalil, M. Rehan Khan, Ashraf S. Gorgey · 2023 · Spinal Cord
  79. The Interplay Between Obesity and Type 2 Diabetes: Common Pathophysiological Mechanisms Contributing to Telomere Shortening
    Stella Baliou, Miruna-Maria Apetroaei, Eleftheria Hatzidaki, Sergey V. Kuzmin, Manolis N. Tzatzarakis, Andreea Letiția Arsene, Aristidis Michael Tsatsakis, Πέτρος Ιωάννου · 2025 · Life
  80. Dietary Cocoa Flavanols Enhance Mitochondrial Function in Skeletal Muscle and Modify Whole-Body Metabolism in Healthy Mice
    Frédéric Daussin, Alexane Cuillerier, Julianne Touron, Samir Bensaid, Bruno Pereira Melo, Ali Al-Rewashdy, Goutham Vasam, Keir J. Menzies, Mary‐Ellen Harper, Elsa Heyman et al. · 2021 · Nutrients
  81. TIMP-1 Dependent Modulation of Metabolic Profiles Impacts Chemoresistance in NSCLC
    Wei Xiao, Pankaj Kumar Ahluwalia, Lan Wang, John Harrison Howard, Ravindra B Kolhe, Amyn M. Rojiani, Mumtaz V. Rojiani · 2022 · Cells
  82. Nuclear Nicotinamide Adenine Dinucleotide Deficiency by Nmnat1 Deletion Impaired Hepatic Insulin Signaling, Mitochondrial Function, and Hepatokine Expression in Mice Fed a High-Fat Diet
    Haibo Dong, Wei Guo, Ruichao Yue, Xinguo Sun, Zhanxiang Zhou · 2024 · Laboratory Investigation
  83. MRPS6 modulates glucose-stimulated insulin secretion in mouse islet cells through mitochondrial unfolded protein response
    Danhong Lin, Jingwen Yu, Leweihua Lin, Qianying Ou, Huibiao Quan · 2023 · Scientific Reports
  84. Haplotype variability in mitochondrial rRNA predisposes to metabolic syndrome
    Petr Pecina, Kristýna Čunátová, Vilma Kaplanová, Guillermo Puertas-Frias, Jan Šilhavý, Kateřina Tauchmannová, Marek Vrbacký, Tomáš Čajka, Ondřej Gahura, Markéta Hlaváčková et al. · 2024 · Communications Biology
  85. The impact of high-fat feeding and parkin overexpression on skeletal muscle mass, mitochondrial respiration, and H2O2 emission
    Olivier Reynaud, Jennifer P Wang, Marie‐Belle Ayoub, Jean‐Philippe Leduc‐Gaudet, Dominique Mayaki, Maude Dulac, Sabah N. A. Hussain, Raynald Bergeron, Gilles Gouspillou · 2022 · American Journal of Physiology-Cell Physiology
  86. Role of the Mitochondrial Pyruvate Carrier in the Occurrence of Metabolic Inflexibility in Drosophila melanogaster Exposed to Dietary Sucrose
    Chloé J. Simard, Mohamed Touaibia, Eric Pierre Allain, Étienne Hébert-Chatelain, Nicolas Pichaud · 2020 · Metabolites
  87. Bistability in fatty-acid oxidation resulting from substrate inhibition
    Fentaw Abegaz, Anne-Claire M. F. Martines, Marcel A. Vieira‐Lara, Melany Ríos-Morales, Dirk‐Jan Reijngoud, Ernst C. Wit, Barbara M. Bakker · 2021 · PLoS Computational Biology
  88. Regulatory Role of Bioactive Compounds from Natural Spices on Mitochondrial Function
    Liguang Han, Chi‐Tang Ho, Muwen Lu · 2025 · Journal of Agricultural and Food Chemistry
  89. Metals in the human liver: An underappreciated risk factor of hepatic insulin resistance and associated pathophysiology
    Rahul Kumar, Ashwin Chinala, Dhruv Grandhe, S. Joseph Endicott, Marcus A. Garcia, Matthew J. Campen, Rama R. Gullapalli · 2025 · Environmental Pollution
  90. Effect of honey bee venom on the histological changes of testes and hormonal disturbance in diabetic mice
    Sattar J. J. AL‐Shaeli, Talal Jabal Hussen, Ali M. Ethaeb · 2022 · Veterinary World
  91. Nrf2 inhibition regulates intracellular lipid accumulation in mouse insulinoma cells and improves insulin secretory function
    Alpana Mukhuty, Samanwita Mandal, Chandrani Fouzder, Snehasis Das, Dipanjan Chattopadhyay, Tanmay Majumdar, Rakesh Kundu · 2023 · Molecular and Cellular Endocrinology
  92. Effect of Aspirin on Mitochondrial Dysfunction and Stress in the Pancreas and Heart of Goto-Kakizaki Diabetic Rats
    Annie John, Layla Amiri, Jasmin Shafarin, Frank Christopher Howarth, Haider Raza · 2021 · Life
  93. An insight of association of insulin resistance with polycystic ovary syndrome
    Barnali Ray Basu, Sanchari Chakraborty, Ankita Samaddar, Nilansu Das, Sudip Kumar Saha · 2021 · Indian Journal of Clinical Anatomy and Physiology
  94. Differential disruption on glucose and insulin metabolism in two rat models of diet-induced obesity, based on carbohydrates or lipids
    Corazón de María Márquez Álvarez, Nancy Patricia Gómez-Crisóstomo, Erick Natividad De la Cruz-Hernández · 2023 · Molecular and Cellular Biochemistry
  95. Review Deciphering the Anticancer Efficacy of Resveratrol and their Associated Mechanisms in Human Carcinoma
    Mohd Arif, Pratibha Pandey, Fahad Khan · 2023 · Endocrine Metabolic & Immune Disorders - Drug Targets
  96. A TRPM2-Driven Signalling Cycle Orchestrates Abnormal Inter-Organelle Crosstalk in Cardiovascular and Metabolic Diseases
    Maali AlAhmad, Esra Shitaw, Asipu Sivaprasadarao · 2025 · Biomolecules
  97. Ceramide metabolism and cardiovascular risk factors: insights into therapeutic strategies
    Shouyi Yang, Yongxin Wu · 2025 · Frontiers in Cardiovascular Medicine
  98. Extracellular ATP Increases Glucose Metabolism in Skeletal Muscle Cells in a P2 Receptor Dependent Manner but Does Not Contribute to Palmitate-Induced Insulin Resistance
    Ana Miguel Cruz, Craig Beall · 2020 · Frontiers in Physiology
  99. In vitro skeletal muscle models for type 2 diabetes
    Christina Y. Sheng, Young Hoon Son, Jeongin Jang, Sung‐Jin Park · 2022 · Biophysics Reviews
  100. The interplay of maternal and offspring obesogenic diets: the impact on offspring metabolism and muscle mitochondria in an outbred mouse model
    Inne Xhonneux, Waleed F. A. Marei, Ben Meulders, S. Andries, Jo Leroy · 2024 · Frontiers in Physiology