Twelve-month outcomes in overweight/obese users with mental disorders following a multi-element treatment including diet, physical activity, and positive thinking: the real-world "an apple a day" controlled trial
Open accessAbstract
The present study aimed to evaluate the 12-month effectiveness of a real-world weight loss transdiagnostic intervention in overweight/obese participants affected by mental disorders under psychopharmacological treatment. We conducted a real-world, controlled, pragmatic outpatient trial. We allocated 58 overweight/obese adults under psychopharmacological treatment from a mental health outpatient unit and 48 overweight/obese adults from a cardiovascular prevention outpatient unit, and assigned them to an intervention or treatment usual as condition (TAU) enriched by life-style advice. Participants in both intervention groups took part in a diet programme (the modified OMNIHeart dietary protocol) and monitoring of regular aerobic activity. A brief group programme ("An Apple a Day" Metacognitive Training, Apple-MCT) was added in the intervention group of participants affected by mental disorders. The primary outcome was weight loss. Secondary outcomes included anthropometric, clinical, and metabolic variables. Psychopathology and health-related quality of life were also evaluated in the psychiatric sample. At 12 months, both intervention groups showed a more marked mean decrease in weight (6.7 kg, SD: 3.57) than the TAU group (0.32 kg, SD: 1.96), and a statistically significant improvement in metabolic variables compared with the control groups. Furthermore, the participants affected by mental disorders included in the intervention group reported improved health-related quality of life. Our findings suggest the need to implement integrated interventions based on a dietary protocol, physical activity, and modification of cognitive style in overweight/obese users with mental disorders.
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There are several trials on weight-loss interventions in patients with chronic physical or mental illnesses, e.g., rheumatoid arthritis, breast cancer, mental disorders, and cardiovascular diseases.
“There are several trials on weight-loss interventions in patients with chronic physical or mental illnesses, e.g., rheumatoid arthritis, breast cancer, mental disorders, and cardiovascular diseases (44–47).”
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References 105 · Cited by 6
Research works printed but not linked: 2
- [100]World Health Organization. Guideline: Sugars Intake for Adults and Children. Geneva: WHO (2015). 25905159
- [101]World Health Organization. WHO Guidelines on Physical Activity Sedentary Behaviour. Geneva: WHO (2020). 33369898
- Authors
- Giusti, L., Bianchini, V., Aggio, A., Mammarella, S., Salza, A., Necozione, S., Alunno, A., Ferri, C., Casacchia, M., & Roncone, R.
- Affiliations
- University of L'Aquila (IT)
- Corresponding author
- Roncone, Rita
- ORCID
- Venue
- Frontiers in Psychiatry
- Publisher
- Frontiers Media SA
- Published
- 2022-08-23
- Volume
- 13
- Pages
- 903759-903759
- ISSN
- 1664-0640 (ISSN-L)
- PMC
- PMC9445251
- OpenAlex
- W4293254629
- Cited by
- 6
- References
- 105
- Citations by year
- 2025: 3 · 2024: 1 · 2023: 2
- FWCI
- 1.32
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Frontiers in Psychiatry (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Archivio Istituzionale della Ricerca - Università degli Studi dell Aquila (submittedVersion, cc-by-nd)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Health Sciences › Health Professions › Pharmacy › Obesity and Health Practices
- Keywords
- obesity, overweight, mental illness, weight loss, transdiagnostic treatment, lifestyle intervention, diet, physical activity, aerobic exercise, metacognitive training, positive thinking, psychopharmacological treatment, health-related quality of life, metabolic parameters, integrated intervention
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