NADPH Oxidases (NOX): An Overview from Discovery, Molecular Mechanisms to Physiology and Pathology

Vermot, Annelise, Petit-Härtlein, Isabelle, Smith, Susan M. E., Fieschi, Franck·2021·Antioxidants

DOI 10.3390/antiox10060890

Cites (457)

Items 201–400 of 457

NAD(P)H Oxidase 1, a Product of Differentiated Colon Epithelial Cells, Can Partially Replace Glycoprotein 91 phox in the Regulated Production of Superoxide by Phagocytes
Miklós Geiszt, Kristen J. Lekstrom, Sebastian Brenner, Stephen M. Hewitt, Raya Dana, Harry L. Malech, Thomas L. Leto · 2003 · The Journal of Immunology
Hematologically important mutations: X-linked chronic granulomatous disease (third update)
Dirk Roos, Douglas Byron Kuhns, Anne Maddalena, Joachim Roesler, Juan Álvaro López, Tadashi Ariga, Tadej Avčin, Martin de Boer, Jacinta C. Bustamante, Antônio Condino‐Neto et al. · 2010 · Blood Cells Molecules and Diseases
Biochemical aspects of phagocytosis in poly-morphonuclear leucocytes. NADH and NADPH oxidation by the granules of resting and phagocytizing cells
Filippo Rossi, Mario Zatti · 1964 · Cellular and Molecular Life Sciences
Redox signaling during hypoxia in mammalian cells
Kimberly A. Smith, Gregory B. Waypa, Paul T. Schumacker · 2017 · Redox Biology
Invading one step at a time: the role of invadopodia in tumor metastasis
Helicia Paz, Navneeta Pathak, Jaemoon Yang · 2013 · Oncogene
A Transverse Tubule NADPH Oxidase Activity Stimulates Calcium Release from Isolated Triads via Ryanodine Receptor Type 1 S -Glutathionylation
Cecilia Hidalgo, Gina Sánchez, Genaro C. Barrientos, Paula Aracena-Parks · 2006 · Journal of Biological Chemistry
Pharmacological characterization of the seven human NOX isoforms and their inhibitors
Fiona Augsburger, Александра Филиппова, Delphine Rasti, Tamara S. Seredenina, Magdalena A. Lam, Ghassan J. Maghzal, Zahia Mahiout, Pidder Jansen‐Dürr, Ulla G. Knaus, James H. Doroshow et al. · 2019 · Redox Biology
Characterization of ThOX Proteins as Components of the Thyroid H2O2-Generating System
Xavier De Deken, Dantong Wang, Jacques E. Dumont, Françoise Miot · 2002 · Experimental Cell Research
Crystal structures and atomic model of NADPH oxidase
Francesca Magnani, S. Nenci, Elisa Millana Fañanás, Marta Ceccon, Elvira Romero, Marco W. Fraaije, Andrea Mattevi · 2017 · Proceedings of the National Academy of Sciences
Novel modular domain PB1 recognizes PC motif to mediate functional protein–protein interactions
Takashi Ito, Yasushi Matsui, Tetsuro Ago, Kazuhisa Ota, Hideki Sumimoto · 2001 · The EMBO Journal
Redox regulation of PTEN and protein tyrosine phosphatases in H2O2‐mediated cell signaling
Seung-Hyun Cho, Chang‐Hun Lee, Younghee Ahn, Hyun‐Jung Kim, Hoeon Kim, Chiyoung Ahn, Kap‐Seok Yang, Seung-Rock Lee · 2004 · FEBS Letters
CHRONIC GRANULOMATOUS DISEASE: CORRELATION BETWEEN PATHOGENESIS AND CLINICAL FINDINGS
Richard Bart Johnston, Robert L. Baehner · 1971 · PEDIATRICS
Role of Nox4 and Nox2 in Hyperoxia-Induced Reactive Oxygen Species Generation and Migration of Human Lung Endothelial Cells
Srikanth Pendyala, Irina A Gorshkova, Peter V. Usatyuk, Donghong He, Arjun Pennathur, J. David Lambeth, Victor John Thannickal, Viswanathan Natarajan · 2008 · Antioxidants and Redox Signaling
A new method for isolating tyrosine kinase substrates used to identify Fish, an SH3 and PX domain‐containing protein, and Src substrate
Peter Lock, Clare L. Abram, Toby Gibson, Sara A. Courtneidge · 1998 · The EMBO Journal
Repairing oxidized proteins in the bacterial envelope using respiratory chain electrons
Alexandra Gennaris, Benjamin Ezraty, Camille Henry, Rym Agrebi, Alexandra Vergnes, Emmanuel Oheix, Julia Bos, Pauline Leverrier, Léon Espinosa, Joanna Szewczyk et al. · 2015 · Nature
Diverse recognition of non‐PxxP peptide ligands by the SH3 domains from p67phox, Grb2 and Pex13p
Keiichiro Kami, Ryu Takeya, Hideki Sumimoto, Daisuke Kohda · 2002 · The EMBO Journal
Absence of both the 91kD and 22kD subunits of human neutrophil cytochrome b in two genetic forms of chronic granulomatous disease
CA Parkos, Mary C. Dinauer, Algirdas J. Jesaitis, Stuart H. Orkin, J T Curnutte · 1989 · Blood
Voltage-gated proton channels maintain pH in human neutrophils during phagocytosis
Deri Morgan, Melania Capasso, Boris Musset · 2009 · Proceedings of the National Academy of Sciences
Activation of the Leukocyte NADPH Oxidase by Phorbol Ester Requires the Phosphorylation of p47 on Serine 303 or 304
Osamu Inanami, Jennifer Linda Johnson, Jeanne K. McAdara, Jamel El Benna, L R Faust, Peter E. Newburger, Bernard M. BABIOR · 1998 · Journal of Biological Chemistry
Processing and Maturation of Flavocytochromeb 558 Include Incorporation of Heme as a Prerequisite for Heterodimer Assembly
Frank R. DeLeo, James B. Burritt, Lixin Yu, Algirdas J. Jesaitis, Mary C. Dinauer, William Michael Nauseef · 2000 · Journal of Biological Chemistry
Reactive oxidants and myeloperoxidase and their involvement in neutrophil extracellular traps
Heather A. Parker, Christine C. Winterbourn · 2013 · Frontiers in Immunology
Hydrogen peroxide-induced apoptosis in HL-60 cells requires caspase-3 activation
Tatsuya Matsura, Masachika Kai, Yasuyoshi Fujii · 1999 · Free Radical Research
NADPH Oxidase Promotes Neutrophil Extracellular Trap Formation in Pulmonary Aspergillosis
Marc Röhm, Melissa J. Grimm, Anthony C. D’Auria, Nikolaos G. Almyroudis, Brahm H. Segal, Constantin Felix Urban · 2014 · Infection and Immunity
Solution structure of the PX domain, a target of the SH3 domain.
Hidekazu Hiroaki, Tetsuro Ago, Takashi Ito, Hideki Sumimoto, Daisuke Kohda · 2001 · Nature Structural Biology
NAD(P)H oxidase plays a crucial role in PDGF‐induced proliferation of hepatic stellate cells
Tohru Adachi, H. Togashi, Akihiko Suzuki, Shigenobu Kasai, Junitsu Ito, K. Sugahara, S. Kawata · 2005 · Hepatology
Nox3 Regulation by NOXO1, p47 , and p67
Guangjie Cheng, Darren R. Ritsick, J. David Lambeth · 2004 · Journal of Biological Chemistry
Nox4 is a Novel Inducible Source of Reactive Oxygen Species in Monocytes and Macrophages and Mediates Oxidized Low Density Lipoprotein–Induced Macrophage Death
Chi Fung Lee, Mu Qiao, Katrin Schröder, Qingwei David Zhao, Reto Asmis · 2010 · Circulation Research
Physiological Stimuli Induce PAD4-Dependent, ROS-Independent NETosis, With Early and Late Events Controlled by Discrete Signaling Pathways
Olga Tatsiy, Patrick P. McDonald · 2018 · Frontiers in Immunology
Nox1 is over‐expressed in human colon cancers and correlates with activating mutations in K‐Ras
Eunice Laurent, James W. McCoy, Roberto A. Macina, Wenhui Liu, Guangjie Cheng, Sylvie Robine, Jackie Papkoff, J. David Lambeth · 2008 · International Journal of Cancer
Genetic disorders coupled to ROS deficiency
O’Neill, Sharon, Brault, Julie, Stasia, Marie-Jose, Knaus, Ulla G. · 2015 · Redox Biology
Hematologically important mutations: The autosomal recessive forms of chronic granulomatous disease (second update)
Dirk Roos, Douglas Byron Kuhns, Anne Maddalena, Jacinta C. Bustamante, Caroline Kannengiesser, Martin de Boer, Karin van Leeuwen, Mustafa Yavuz Köker, Baruch Wolach, Joachim Roesler et al. · 2010 · Blood Cells Molecules and Diseases
Autophagy Protein Rubicon Mediates Phagocytic NADPH Oxidase Activation in Response to Microbial Infection or TLR Stimulation
Chul‐Su Yang, Jong‐Soo Lee, Mary A. Rodgers, Chan‐Ki Min, June‐Yong Lee, Hee Jin Kim, Kwang-Hoon Lee, Chul‐Joong Kim, Byung‐Ha Oh, Ebrahim Zandi et al. · 2012 · Cell Host & Microbe
Cellular and temporal expression of NADPH oxidase (NOX) isotypes after brain injury
Sean J. Cooney, Sara L Bermudez-Sabogal, Kimberly R. Byrnes · 2013 · Journal of Neuroinflammation
NADPH oxidase subunit, gp91phox homologue, preferentially expressed in human colon epithelial cells
Hideaki Kikuchi, Mituru Hikage, Hitoshi Miyashita, Manabu Fukumoto · 2000 · Gene
Constitutive NADPH-Dependent Electron Transferase Activity of the Nox4 Dehydrogenase Domain
Nisimoto, Yukio, Jackson, Heather M., Ogawa, Hisamitsu, Kawahara, Tsukasa, Lambeth, J. David · 2010 · Biochemistry
Apoptosis, reproductive failure, and oxidative stress in Chinese hamster ovary cells with compromised genomic integrity.
Charles L. Limoli, A Hartmann, L.B. Shephard, Chin‐Rang Yang, David A. Boothman, Jim Bartholomew, William F. Morgan · 1998 · PubMed
The Cytosolic Component p47 Is Not a Sine Qua Non Participant in the Activation of NADPH Oxidase but Is Required for Optimal Superoxide Production
Vasilij Koshkin, Ofra Lotan, Edgar Pick · 1996 · Journal of Biological Chemistry
Nox enzymes from fungus to fly to fish and what they tell us about Nox function in mammals
Jesús Aguirre, J. David Lambeth · 2010 · Free Radical Biology and Medicine
NADPH oxidases in Parkinson’s disease: a systematic review
Karim Bélarbi, Elodie Cuvelier, A. Destée, Bernard Gressier, Marie‐Christine Chartier‐Harlin · 2017 · Molecular Neurodegeneration
Genetics and immunopathology of chronic granulomatous disease
M. Stasia, Xing-Jun Li · 2008 · Seminars in Immunopathology
NADPH Oxidase Activity Is Independent of p47
Jennifer L. R. Freeman, J. David Lambeth · 1996 · Journal of Biological Chemistry
Genomic instability and catalase gene amplification induced by chronic exposure to oxidative stress.
Clayton R. Hunt, Julia E. Sim, Shannon J. Sullivan, T. Featherstone, Wendy L. Golden, C Von Kapp-Herr, Randy A. Hock, R A Gomez, A. Parsian, Douglas R. Spitz · 1998 · PubMed
Mapping sites of interaction of p47-phox and flavocytochrome b with random-sequence peptide phage display libraries.
DeLeo, F R, Yu, L, Burritt, J B, Loetterle, L R, Bond, C W, Jesaitis, A J, Quinn, M T · 1995 · Proceedings of the National Academy of Sciences
Cell Proliferation, Reactive Oxygen and Cellular Glutathione
Day, Regina M., Suzuki, Yuichiro J. · 2005 · Dose-Response
Assembly of the neutrophil respiratory burst oxidase: A direct interaction between p67 PHOX and cytochrome b 558 II
Pham My‐Chan Dang, Andrew R. Cross, Mark T. Quinn, Bernard M. BABIOR · 2002 · Proceedings of the National Academy of Sciences
HIF-1α signaling is augmented during intermittent hypoxia by induction of the Nrf2 pathway in NOX1-expressing adenocarcinoma A549 cells
Malec, Viktor, Gottschald, Oana R., Li, Shu, Rose, Frank, Seeger, Werner, Hänze, Jörg · 2010 · Free Radical Biology and Medicine
NADPH Oxidases: Insights into Selected Functions and Mechanisms of Action in Cancer and Stem Cells
Magdalena Skonieczna, Tomasz Hejmo, Aleksandra Poterała-Hejmo, Artur Cieślar‐Pobuda, Rafał Jakub Bułdak · 2017 · Oxidative Medicine and Cellular Longevity
A central role for the endothelial NADPH oxidase in atherosclerosis
Jamie W. Meyer, Mark E. Schmitt · 2000 · FEBS Letters
Expression of NADPH oxidase homologues and accessory genes in human cancer cell lines, tumours and adjacent normal tissues
Agnes N. Juhasz, Yun Ge, Susan Markel, Alice Chiu, Linda Matsumoto, Josephus N.A. van Balgooy, Krishnendu Roy, James H. Doroshow · 2009 · Free Radical Research
Crystal Structure of the Rac1−RhoGDI Complex Involved in NADPH Oxidase Activation,
Sylvestre Grizot, Julien Fauré, Franck Fieschi · 2001 · Biochemistry
The subcellular distribution and some properties of the cytochrome b component of the microbicidal oxidase system of human neutrophils
Anthony Walter Segal, Owen T.G. Jones · 1979 · Biochemical Journal
Targeting Vascular NADPH Oxidase 1 Blocks Tumor Angiogenesis through a PPARα Mediated Mechanism
Garrido-Urbani, Sarah, Jemelin, Stephane, Deffert, Christine, Carnesecchi, Stéphanie, Basset, Olivier, Szyndralewiez, Cédric, Heitz, Freddy, Page, Patrick, Montet, Xavier, Michalik, Liliane et al. · 2011 · PLoS ONE
Phosphatidic Acid-mediated Phosphorylation of the NADPH Oxidase Component p47-phox
Kristin A. Waite, Reidar Wallin, Diane Qualliotine‐Mann, Linda C. McPhail · 1997 · Journal of Biological Chemistry
Direct Involvement of the Small GTPase Rac in Activation of the Superoxide-producing NADPH Oxidase Nox1
Kei Miyano, Noriko Ueno, Ryu Takeya, Hideki Sumimoto · 2006 · Journal of Biological Chemistry
The superoxide-generating oxidase of leucocytes. NADPH-dependent reduction of flavin and cytochrome b in solubilized preparations
Andrew R. Cross, John F. Parkinson, Owen T.G. Jones · 1984 · Biochemical Journal
Nox, Reactive Oxygen Species and Regulation of Vascular Cell Fate
Denise Burtenshaw, Roya Hakimjavadi, Eileen M. Redmond, Paul Aidan Cahill · 2017 · Antioxidants
Superoxide Anion Radical-Triggered Ca2+ Release from Cardiac Sarcoplasmic Reticulum through Ryanodine Receptor Ca2+ Channel
Midori Kawakami, Eiichiro Okabe · 1998 · Molecular Pharmacology
Chronic Granulomatous Disease: Lessons from a Rare Disorder
Brahm H. Segal, Paul A. Veys, Harry L. Malech, Morton Jerome Cowan · 2010 · Transplantation and Cellular Therapy
cAMP-response Element-binding Protein Mediates Acid-induced NADPH Oxidase NOX5-S Expression in Barrett Esophageal Adenocarcinoma Cells
Xiaoying Fu, David G. Beer, José Behar, Jack R. Wands, David J. Lambeth, Weibiao Cao · 2006 · Journal of Biological Chemistry
Interferon-γ activates transcription of NADPH oxidase 1 gene and upregulates production of superoxide anion by human large intestinal epithelial cells
Yuki Kuwano, Tsukasa Kawahara, Hironori Yamamoto, Shigetada Teshima-Kondo, Kumiko Tominaga, Kiyoshi Masuda, Kyoichi Kishi, Kyoko Morita, Kazuhito Rokutan · 2005 · American Journal of Physiology-Cell Physiology
Mechanism of the superoxide-producing oxidase of neutrophils. O2 is necessary for the fast reduction of cytochrome b-245 by NADPH
Andrew R. Cross, John F. Parkinson, Owen T.G. Jones · 1985 · Biochemical Journal
A structural model for the nucleotide binding domains of the flavocytochrome b–245 β‐chain
William Ramsay Taylor, David T. Jones, Anthony Walter Segal · 1993 · Protein Science
Receptor‐stimulated oxidation of SHP‐2 promotes T‐cell adhesion through SLP‐76–ADAP
Jaeyul Kwon, Cheng‐Kui Qu, Jin-Soo Maeng, Rustom Falahati, Chunghee Lee, Mark S Williams · 2005 · The EMBO Journal
Rap1a Null Mice Have Altered Myeloid Cell Functions Suggesting Distinct Roles for the Closely Related Rap1a and 1b Proteins
Yu Li, Jingliang Yan, Pradip K.R De, Hua‐Chen Chang, 明山内, Kent W. Christopherson, Nivanka C. Paranavitana, Xiaodong Peng, Chaekyun Kim, Veerendra Munugulavadla et al. · 2007 · The Journal of Immunology
Innate Immune Responses to Tuberculosis
Jeffrey S. Schorey, Larry S. Schlesinger · 2016 · Microbiology Spectrum
The function of the NADPH oxidase of phagocytes and its relationship to other NOXs in plants, invertebrates, and mammals
Anthony Walter Segal · 2007 · The International Journal of Biochemistry & Cell Biology
Interaction between 24-hydroxycholesterol, oxidative stress, and amyloid-β in amplifying neuronal damage in Alzheimer’s disease: three partners in crime
Paola Gamba, Gabriella Leonarduzzi, Elena Tamagno, Michela Guglielmotto, Gabriella Testa, Barbara Sottero, Simona Gargiulo, Fiorella Biasi, Alessandro Mauro, José Viña et al. · 2011 · Aging Cell
Inhibition of Rap1A Binding to Cytochrome b 558 of NADPH Oxidase by Phosphorylation of Rap1A
Gary Bokoch, Lawrence A. Quilliam, Benjamin P. Bohl, Algirdas J. Jesaitis, Mark T. Quinn · 1991 · Science
Cytochrome b−245 of the Neutrophil Superoxide-generating System Contains Two Nonidentical Hemes
Andrew R. Cross, Julie Rae, John T. Curnutte · 1995 · Journal of Biological Chemistry
Activation of the Superoxide Forming NADPH Oxidase in a Cell-free System by Sodium Dodecyl Sulfate
Sally Shpungin, Iris Dotan, Arie Abo, Edgar Pick · 1989 · Journal of Biological Chemistry
Multiple SH3 domain interactions regulate NADPH oxidase assembly in whole cells.
Isabelle de Mendez, Anthony G. Adams, Robert A. Sokolic, Harry L. Malech, Thomas L. Leto · 1996 · The EMBO Journal
Cytochrome b-245 from human neutrophils is a glycoprotein
Angela Harper, Martin F. Chaplin, Anthony Walter Segal · 1985 · Biochemical Journal
Inactivation of a bacterial virulence pheromone by phagocyte-derived oxidants: New role for the NADPH oxidase in host defense
Jacob M. Rothfork, Graham S. Timmins, Michael N. Harris, Xian Chen, Aldons Jake Lusis, Michael J. Otto, Ambrose L. Cheung, Hattie D. Gresham · 2004 · Proceedings of the National Academy of Sciences
Toll-Like Receptor 4 Mutation Protects Obese Mice Against Endothelial Dysfunction by Decreasing NADPH Oxidase Isoforms 1 and 4
Chaofan Liang, Jacky TC Liu, Yu Wang, Aimin Xu, Paul M. Vanhoutte · 2013 · Arteriosclerosis Thrombosis and Vascular Biology
STIM, ORAI AND TRPC CHANNELS IN THE CONTROL OF CALCIUM ENTRY SIGNALS IN SMOOTH MUSCLE
Youjun Wang, Xiaoxiang Deng, Thamara Hewavitharana, Jonathan Soboloff, Donald L. Gill · 2008 · Clinical and Experimental Pharmacology and Physiology
Pyridine nucleotide-dependent superoxide production by a cell-free system from human granulocytes.
Babior, B M, Curnutte, J T, Kipnes, B S · 1975 · Journal of Clinical Investigation
The Role of Hydrogen Peroxide and Peroxiredoxins throughout the Cell Cycle
Sukyeong Heo, Suree Kim, Dongmin Kang · 2020 · Antioxidants
Atrial Natriuretic Peptide Induces Mitogen-Activated Protein Kinase Phosphatase-1 in Human Endothelial Cells via Rac1 and NAD(P)H Oxidase/Nox2-Activation
Robert Fürst, Corinna Brueckl, Wolfgang Michael Kuebler, Stefan Zahler A, Florian Krötz, Agnes Görlach, Angelika M. Vollmar, Alexandra K. Kiemer · 2004 · Circulation Research
Function of wild-type or mutant Rac2 and Rap1a GTPases in differentiated HL60 cell NADPH oxidase activation
Theodore G. Gabig, Colin Crean, P.L. Mantel, R Rosli · 1995 · Blood
Novel p47 phox -Related Organizers Regulate Localized NADPH Oxidase 1 (Nox1) Activity
Davide Gianni, Begoña Díaz, Nicolas Taulet, Bruce J. Fowler, Sara A. Courtneidge, Gary Bokoch · 2009 · Science Signaling
Peroxisomal Proliferator-activated Receptor-α-dependent Inhibition of Endothelial Cell Proliferation and Tumorigenesis
Ambra Pozzi, María Raquel Ibáñez, Arnaldo Gatica, Shilin Yang, Shouzuo D. Wei, Shaojun Mei, John Russell Falck, Jorge H. Capdevila · 2007 · Journal of Biological Chemistry
Induction of Chromosomal Instability by Chronic Oxidative Stress
Charles L. Limoli, Erich Giedzinski · 2003 · Neoplasia
The Many Faces of Rap1 GTPase
Anna Jaśkiewicz, Beata Pająk, Arkadiusz Orzechowski · 2018 · International Journal of Molecular Sciences
Assembly of the neutrophil respiratory burst oxidase: A direct interaction between p67 PHOX and cytochrome b 558
Pham My‐Chan Dang, Andrew R. Cross, Bernard M. BABIOR · 2001 · Proceedings of the National Academy of Sciences
pH regulation and beyond: unanticipated functions for the voltage-gated proton channel, HVCN1
Melania Capasso, Thomas E. DeCoursey, Martin J.S. Dyer · 2010 · Trends in Cell Biology
[Chronic granulomatous disease].
Farhat Ck, J Pasternak, Carvalho Ade A · 1973 · PubMed
TLR-4 Signalling Accelerates Colon Cancer Cell Adhesion via NF-κB Mediated Transcriptional Up-Regulation of Nox-1
Daire O’Leary, Lavinia Bhatt, John F. Woolley, David R. Gough, Jiang H. Wang, Thomas G. Cotter, Henry Paul Redmond · 2012 · PLoS ONE
The Cytosolic Activating Factors p47phox and p67phox Have Distinct Roles in the Regulation of Electron Flow in NADPH Oxidase
Andrew R. Cross, John T. Curnutte · 1995 · Journal of Biological Chemistry
The Heme Component of the Neutrophil NADPH Oxidase Complex Is a Target for Aryliodonium Compounds
Jacques Doussière, Jacques Gaillard, Pierre V. Vignais · 1999 · Biochemistry
Analysis of Activation-induced Conformational Changes in p47 Using Tryptophan Fluorescence Spectroscopy
Steve D. Swain, Sam L. Helgerson, Angela R. Davis, Laura K. Nelson, Mark T. Quinn · 1997 · Journal of Biological Chemistry
The prolyl isomerase Pin1 acts as a novel molecular switch for TNF-α–induced priming of the NADPH oxidase in human neutrophils
Tarek Boussetta, Marie‐Anne Gougerot‐Pocidalo, Gilles Hayem et al. · 2010 · Blood
Growth Factors Outside of the Platelet-derived Growth Factor (PDGF) Family Employ Reactive Oxygen Species/Src Family Kinases to Activate PDGF Receptor α and Thereby Promote Proliferation and Survival of Cells
Hetian Lei, Andrius Kazlauskas · 2009 · Journal of Biological Chemistry
NADPH Oxidase 1, a Novel Molecular Source of ROS in Hippocampal Neuronal Death in Vascular Dementia
Dong-Hee Choi, Kyoung-Hee Lee, Ji-Hye Kim, Ju-Ha Seo, Hahn Young Kim, Chan Young Shin, Jung‐Soo Han, Seol‐Heui Han, Yoon-Seong Kim, Jongmin Lee · 2013 · Antioxidants and Redox Signaling
Evolution of the Ferric Reductase Domain (FRD) Superfamily: Modularity, Functional Diversification, and Signature Motifs
Xuezhi Zhang, Karl‐Heinz Krause, Ioannis Xénarios, Thierry Soldati, Brigitte Boeckmann · 2013 · PLoS ONE
Chemoattractant stimulus-response coupling
John R. Didsbury, Ronald J. Uhing, Ralph Snyderman · 1992 · Springer eBooks
Wild-type and mutant p53 differentially regulate NADPH oxidase 4 in TGF-β-mediated migration of human lung and breast epithelial cells
Howard E. Boudreau, Benjamin W. Casterline, Devin J. Burke, TL Leto · 2014 · British Journal of Cancer
Identification of novel Nox4 splice variants with impact on ROS levels in A549 cells
Parag Goyal, Norbert Weißmann, Frank Rose, Friedrich Grimminger, Hans‐Joachim Schäfers, Werner Seeger, Jörg Hänze · 2005 · Biochemical and Biophysical Research Communications
Molecular interaction between ryanodine receptor and glycoprotein triadin involves redox cycling of functionally important hyperreactive sulfhydryls
Guozhen Liu, Isaac N. Pessah · 1994 · Journal of Biological Chemistry
Effect of hydrogen peroxide on Ca2+ mobilisation in human platelets through sulphydryl oxidation dependent and independent mechanisms
Pedro Cosme Redondo, Ginés María Salido, Juan Antonio Rosado, José Antonio Pariente · 2003 · Biochemical Pharmacology
Role of the Rho GTPase Rac in the activation of the phagocyte NADPH oxidase
Edgar Pick · 2014 · Small GTPases
The Ca2+-sensing Receptor Activates Cytosolic Phospholipase A2 via a Gqα-dependent ERK-independent Pathway
Mary E. Handlogten, Chunfa Huang, Naoki Shiraishi · 2001 · Journal of Biological Chemistry
NADPH oxidases in Eukaryotes: red algae provide new hints!
Cécile Hervé, Thierry Tonon, Jonas Collén, Erwan Corre, Catherine Boyen · 2005 · Current Genetics
Control of Hepatic Nuclear Superoxide Production by Glucose 6-Phosphate Dehydrogenase and NADPH Oxidase-4
Netanya Y. Spencer, Ziying Yan, Ryan L. Boudreau, Yulong Zhang, Meihui Luo, Qiang Li, Xin Tian, Ajay M. Shah, Robin L. Davisson, Beverly L. Davidson et al. · 2011 · Journal of Biological Chemistry
Cognitive impairment in humanized APP×PS1 mice is linked to Aβ1–42 and NOX activation
Bruce-Keller, Annadora J., Gupta, Sunita, Knight, Alecia G., Beckett, Tina L., McMullen, Jessica M., Davis, Paulina R., Murphy, M. Paul, Van Eldik, Linda J., St Clair, Daret, Keller, Jeffrey N. · 2011 · Neurobiology of Disease
Hydroxyl radical‐induced apoptosis in human tumor cells is associated with telomere shortening but not telomerase inhibition and caspase activation
Jianguo Ren, Huili Xia, Tom Just, Yao‐Ren Dai · 2001 · FEBS Letters
Human neutrophil cytochrome b contains multiple hemes. Evidence for heme associated with both subunits.
Mark T. Quinn, ML Mullen, Algirdas J. Jesaitis · 1992 · Journal of Biological Chemistry
Phosphorylation of p22 Is Mediated by Phospholipase D-dependent and -independent Mechanisms
Debra S. Regier, Dianne G. Greene, Susan Sergeant, Algirdas J. Jesaitis, Linda C. McPhail · 2000 · Journal of Biological Chemistry
NADPH oxidase 5 (NOX5) interacts with and is regulated by calmodulin
Fabiana Tirone, Jos A. Cox · 2007 · FEBS Letters
Mapping of Functional Domains in the p22 Subunit of Flavocytochrome b 559 Participating in the Assembly of the NADPH Oxidase Complex by “Peptide Walking”
Iris M. Dahan, Irina Issaeva, Yara Gorzalczany, Natalia Sigal, Miriam Hirshberg, Edgar Pick · 2002 · Journal of Biological Chemistry
Molecular Recognition in Dimerization between PB1 Domains
Yukiko Noda, Motoyuki Kohjima, Tomoko Izaki, Kazuhisa Ota, Sosuke Yoshinaga, Fuyuhiko Inagaki, Takashi Ito, Hideki Sumimoto · 2003 · Journal of Biological Chemistry
NADPH oxidase modulates myocardial Akt, ERK1/2 activation, and angiogenesis after hypoxia-reoxygenation
Jian-Xiong Chen, Heng Zeng, Qinhui Tuo, Heidi Yu, Barbara O. Meyrick, Judy Lynn Aschner · 2007 · American Journal of Physiology-Heart and Circulatory Physiology
Solubilization of the O2(-)-forming activity responsible for the respiratory burst in human neutrophils.
Theodore G. Gabig, Ruby S. Kipnes, Bernard M. BABIOR · 1978 · Journal of Biological Chemistry
NMR Solution Structure of the Tandem Src Homology 3 Domains of p47 Complexed with a p22 -derived Proline-rich Peptide
Kenji Ogura, Ikuo Nobuhisa, Satoru Yuzawa, Ryu Takeya, Shinnosuke Torikai, Kazuya Saikawa, Hideki Sumimoto, Fuyuhiko Inagaki · 2005 · Journal of Biological Chemistry
The Antibacterial Activity of Human Neutrophils and Eosinophils Requires Proton Channels but Not BK Channels
Jon Femling, Vladimir V. Cherny, Deri Morgan, Balázs Rada, A. Paige Davis Volk, Gábor Czirják, Péter Enyedi, Sarah K. England, Jessica G. Moreland, Erzsébet Ligeti et al. · 2006 · The Journal of General Physiology
H2O2 Metabolism in Normal Thyroid Cells and in Thyroid Tumorigenesis: Focus on NADPH Oxidases
Ildikó Szántó, Marc Philippe Pusztaszeri, Maria Mavromati · 2019 · Antioxidants
Hydrogen peroxide reactivity and specificity in thiol-based cell signalling
Christine C. Winterbourn · 2020 · Biochemical Society Transactions
Rac, a small guanosine triphosphate–binding protein, and p21-activated kinase are activated during platelet spreading on collagen-coated surfaces: roles of integrin α2β1
Katsue Suzuki‐Inoue, Yutaka Yatomi, Naoki Asazuma · 2001 · Blood
Critical roles for p22phox in the structural maturation and subcellular targeting of Nox3
Yoko Nakano, Botond Bánfi, Algirdas J. Jesaitis, Mary C. Dinauer, Lee‐Ann H. Allen, William Michael Nauseef · 2007 · Biochemical Journal
Caenorhabditis elegans and Human Dual Oxidase 1 (DUOX1) “Peroxidase” Domains
Jennifer L. Meitzler, Paul R. Ortiz de Montellano · 2009 · Journal of Biological Chemistry
A Regulated Adaptor Function of p40phox: Distinct p67phoxMembrane Targeting by p40phoxand by p47phox
Takehiko Ueyama, Toshihiko Tatsuno, Takumi Kawasaki · 2006 · Molecular Biology of the Cell
Mechanism of protein kinase C activation by phosphatidylinositol 4,5-bisphosphate
Myung Ho Lee, Robert M. Bell · 1991 · Biochemistry
Mice Deficient in Dual Oxidase Maturation Factors Are Severely Hypothyroid
Helmut Grasberger, Xavier De Deken, Olga Barca‐Mayo, Houssam Raad, Mia C. Weiss, Xiao-Hui Liao, Samuel Refetoff · 2012 · Molecular Endocrinology
Duox expression and related H2O2 measurement in mouse thyroid: onset in embryonic development and regulation by TSH in adult
Milutin Milenkovic, Xavier De Deken, Ling Jin, Mario De Felice, Roberto Di Lauro, Jacques E. Dumont, Bernard Corvilain, Françoise Miot · 2007 · Journal of Endocrinology
Deletion Mutagenesis of p22 Subunit of Flavocytochrome b558
Yanmin Zhu, Christophe C. Marchal, Amy-Jo Casbon, Natalie D. Stull, Katharina von Löhneysen, Ulla G. Knaus, Algirdas J. Jesaitis, Sally J. McCormick, William Michael Nauseef, Mary C. Dinauer · 2006 · Journal of Biological Chemistry
Effects of p47 C Terminus Phosphorylations on Binding Interactions with p40 and p67
C. Massenet, Sylvie Chenavas, Claudine Cohen‐Addad, Marie‐Claire Dagher, Gérard Brandolin, Eva Pebay‐Peyroula, Franck Fieschi · 2005 · Journal of Biological Chemistry
NADPH oxidase homologs are required for normal cell differentiation and morphogenesis in Dictyostelium discoideum
Bernard Lardy, Mireille Bof, Laurence Aubry, Marie Hélène Paclet, Françoise Morel, Michel Satre, Gérard Klein · 2005 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Effect of Iodide on Nicotinamide Adenine Dinucleotide Phosphate Oxidase Activity and Duox2 Protein Expression in Isolated Porcine Thyroid Follicles
Stanislas C. Morand, Mokhtar Chaaraoui, Jacques Kaniewski, Danielle Dème, Renée Ohayon, Marie‐Sophie Noël‐Hudson, Alain Virion, Corinne Dupuy · 2003 · Endocrinology
NADPH Oxidase and Neurodegeneration
Marina S. Hernandes, Luiz R.G. Britto · 2012 · Current Neuropharmacology
The mechanism for activation of the neutrophil NADPH‐oxidase by the peptides formyl‐Met‐Leu‐Phe and Trp‐Lys‐Tyr‐Met‐Val‐Met differs from that for interleukin‐8
Huamei Fu, Johan Bylund, Anna Karlsson, Sara Pellmé, Cláes Dahlgren · 2004 · Immunology
Purification of the 260 kDa cytosolic complex involved in the Superoxide production of guinea pig neutrophils
Akimasa Someya, Isao Nagaoka, Tatsuhisa Yamashita · 1993 · FEBS Letters
A Phosphatidic Acid-activated Protein Kinase and Conventional Protein Kinase C Isoforms Phosphorylate p22 , an NADPH Oxidase Component
Debra S. Regier, Kristin A. Waite, Reidar Wallin, Linda C. McPhail · 1999 · Journal of Biological Chemistry
NADPH Oxidase and Neurodegeneration
Marina S. Hernandes, Luiz R.G. Britto · 2012 · Current Neuropharmacology
Ethyl Pyruvate Rescues Nigrostriatal Dopaminergic Neurons by Regulating Glial Activation in a Mouse Model of Parkinson’s Disease
Sue Hee Huh, Young Cheul Chung, Ying Piao, Min Y Jin, Hyo Jin Son, Nam Soo Yoon, Joo Y. Hong, Youngmi Kim Pak, Yoon S. Kim, Jong Ki Hong et al. · 2011 · The Journal of Immunology
Critical Role of NADPH Oxidase-derived Reactive Oxygen Species in Generating Ca2+ Oscillations in Human Aortic Endothelial Cells Stimulated by Histamine
Qinghua Hu, Zu‐Xi Yu, Victor J. Ferrans, Kazuyo Takeda, Kaikobad Irani, Roy Charles Ziegelstein · 2002 · Journal of Biological Chemistry
Nox4- and Nox2-dependent oxidant production is required for VEGF-induced SERCA cysteine-674 S-glutathiolation and endothelial cell migration
Evangelista, Alicia M., Thompson, Melissa D., Bolotina, Victoria M., Tong, XiaoYong, Cohen, Richard A. · 2012 · Free Radical Biology and Medicine
Targeting the Progression of Parkinsons Disease
George, J., Mok, S., Moses, D., Wilkins, S., Bush, A., Cherny, R., Finkelstein, D. · 2009 · Current Neuropharmacology
NOX4 Expression in Human Microglia Leads to Constitutive Generation of Reactive Oxygen Species and to Constitutive IL-6 Expression
Bin Li, Karen Bedard, Silvia Sorce, Boris Hinz, Michel Dubois‐Dauphin, Karl‐Heinz Krause · 2009 · Journal of Innate Immunity
Modification of proteins and lipids by myeloperoxidase
Stanley L. Hazen, Fong‐Fu Hsu, Joseph P. Gaut, Jan R. Crowley, Jay W. Heinecke · 1999 · Methods in enzymology on CD-ROM/Methods in enzymology
Thrombin-induced MCP-1 Expression Involves Activation of the p22phox-containing NADPH Oxidase in Human Vascular Smooth Muscle Cells
Christiane Viedt, K. Nguyen, Stefani Beer · 2001 · Thrombosis and Haemostasis
Electron Transfer Across the O2- Generating Flavocytochrome b of Neutrophils. Evidence for a Transition from a Low-Spin State to a High-Spin State of the Heme Iron Component
Jacques Doussière, Jacques Gaillard, Pierre V. Vignais · 1996 · Biochemistry
The NOX Family of Proteins Is Also Present in Bacteria
Christine Hajjar, Mickaël V. Cherrier, Gaëtan Dias Mirandela, Isabelle Petit-Härtlein, Marie José Stasia, Juan Carlos Fontecilla-Camps, Franck Fieschi, Jérôme Dupuy · 2017 · mBio
Anionic Amphiphile-independent Activation of the Phagocyte NADPH Oxidase in a Cell-free System by p47 and p67 , Both in C Terminally Truncated Forms
Kenichiro Hata, Takashi Ito, Koichiro Takeshige, Hideki Sumimoto · 1998 · Journal of Biological Chemistry
Activation of the superoxide forming NADPH oxidase in a cell-free system by sodium dodecyl sulfate. Characterization of the membrane-associated component.
Edgar Pick, Yael Bromberg, Sally Shpungin · 1987 · Journal of Biological Chemistry
NADPH oxidase 1-dependent ROS is crucial for TLR4 signaling to promote tumor metastasis of non-small cell lung cancer
Xiyu Liu, Changyan Pei, Song Yan, Guifeng Liu, Gang Liu, Wenqing Chen, Youbin Cui, Yahui Liu · 2015 · Tumor Biology
Mitochondrial redox plays a critical role in the paradoxical effects of NAPDH oxidase-derived ROS on coronary endothelium
Ehtesham Shafique, Anali Galluce Torina, Karla Reichert, Bonnie J. Colantuono, Nasifa Nur, Khawaja Zeeshan, Vani S. Ravichandran, Yuhong Liu, Jun Feng, Khawaja Zeeshan et al. · 2016 · Cardiovascular Research
CHANGES IN THE METABOLIC PATTERN OF POLYMORPHO-NUCLEAR LEUCOCYTES DURING PHAGOCYTOSIS.
Filippo Rossi, Mario Zatti · 1964 · PubMed
Increased oxidative stress in the streptozotocin-induced diabetic apoE-deficient mouse: Changes in expression of NADPH oxidase subunits and eNOS
Hong Ding, Michael Hashem, Chris R. Triggle · 2007 · European Journal of Pharmacology
A molecular mechanism for autoinhibition of the tandem SH3 domains of p47phox, the regulatory subunit of the phagocyte NADPH oxidase
Satoru Yuzawa, Nobuo N. Suzuki, Yūko Fujioka, Kenji Ogura, Hideki Sumimoto, Fuyuhiko Inagaki · 2004 · Genes to Cells
Chemoattractant-stimulated GTPase activity is decreased on membranes from polymorphonuclear leukocytes incubated in chemoattractant
Mary W. Wilde, Kenneth E. Carlson, David R. Manning · 1989 · Journal of Biological Chemistry
Activation of store-operated ICRAC by hydrogen peroxide
Morten Grupe, George Myers, Reinhold Penner, Andrea Fleig · 2010 · Cell Calcium
Lipopolysaccharide (LPS)-mediated Angiopoietin-2-dependent Autocrine Angiogenesis Is Regulated by NADPH Oxidase 2 (Nox2) in Human Pulmonary Microvascular Endothelial Cells
Heather L. Menden, Scott R. Welak, Stephanie M. Cossette, Ramani Ramchandran, Venkatesh Sampath · 2015 · Journal of Biological Chemistry
Full‐length p40phox structure suggests a basis for regulation mechanism of its membrane binding
Kazuya Honbou, Reiko Minakami, Satoru Yuzawa · 2007 · The EMBO Journal
Structures of mouse DUOX1–DUOXA1 provide mechanistic insights into enzyme activation and regulation
Ji Sun · 2020 · Nature Structural & Molecular Biology
Endothelial NADPH oxidase 4 mediates vascular endothelial growth factor receptor 2-induced intravitreal neovascularization in a rat model of retinopathy of prematurity.
Haibo Wang, Zhihong Yang, Yanchao Jiang, M. Elizabeth Hartnett · 2014 · Europe PMC (PubMed Central)
Molecular analysis of 9 new families with chronic granulomatous disease caused by mutations in CYBA, the gene encoding p22phox
Julie Rae, Deborah Noack, Paul G. Heyworth, Beverly A. Ellis, John T. Curnutte, Andrew R. Cross · 2000 · Blood
p22-phox-deficient chronic granulomatous disease: reconstitution by retrovirus-mediated expression and identification of a biosynthetic intermediate of gp91-phox
CD Porter, M. H. Parkar, Arthur J. Verhoeven, Roland J. Levinsky, Mary K. Collins, Christine Kinnon · 1994 · Blood
The gp91 Component of NADPH Oxidase Is Not the Voltage-gated Proton Channel in Phagocytes, but It Helps
Thomas E. DeCoursey, Vladimir V. Cherny, Deri Morgan, Ben Z. Katz, Mary C. Dinauer · 2001 · Journal of Biological Chemistry
TNF-α dilates cerebral arteries via NAD(P)H oxidase-dependent Ca2+ spark activation
Sergey Y. Cheranov, Jonathan H. Jaggar · 2005 · American Journal of Physiology-Cell Physiology
Consequences of the structure of the cytochrome b6f complex for its charge transfer pathways
William A. Cramer, Huamin Zhang · 2006 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
Activation of the Superoxide-Generating NADPH Oxidase by Chimeric Proteins Consisting of Segments of the Cytosolic Component p67phoxand the Small GTPase Rac1
Nathalie Alloul, Yara Gorzalczany, Michal Itan, Natalia Sigal, Edgar Pick · 2001 · Biochemistry
CXCR4, but not CXCR7, Discriminates Metastatic Behavior in Non–Small Cell Lung Cancer Cells
Young H. Choi, Marie D. Burdick, Brett A. Strieter, Borna Mehrad, Robert M. Strieter · 2013 · Molecular Cancer Research
The cytochrome b and flavin content and properties of the O2−-forming NADPH oxidase solubilized from activated neutrophils
Paolo Bellavite, Andrew R. Cross, Maria C. Serra, Anna Davoli, Owen T.G. Jones, Filippo Rossi · 1983 · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology
Site-Specific Inhibitors of NADPH Oxidase Activity and Structural Probes of Flavocytochrome b : Characterization of Six Monoclonal Antibodies to the p22 phox Subunit
Ross M. Taylor, James B. Burritt, Danas Baniulis, Thomas R. Foubert, Connie I. Lord, Mary C. Dinauer, Charles A. Parkos, Algirdas J. Jesaitis · 2004 · The Journal of Immunology
Oxidants in Physiological Processes
Ulla G. Knaus · 2020 · Handbook of experimental pharmacology
NADPH-oxidase activation in murine neutrophils via formyl peptide receptors
Johan Bylund, Marie Samuelsson, L. Vincent Collins · 2003 · Experimental Cell Research
A Two-component NADPH Oxidase (NOX)-like System in Bacteria Is Involved in the Electron Transfer Chain to the Methionine Sulfoxide Reductase MsrP
Céline Juillan‐Binard, Antoine Picciocchi, Jean‐Pierre Andrieu, Jérôme Dupuy, Isabelle Petit-Härtlein, Christelle Caux‐Thang, Corinne Vivès, Vincent Nivière, Franck Fieschi · 2016 · Journal of Biological Chemistry
Cytochrome b558-negative, autosomal recessive chronic granulomatous disease: two new mutations in the cytochrome b558 light chain of the NADPH oxidase (p22-phox).
Martin de Boer, A de Klein, Johann Peter Hossle, Reinhard A Seger, L Corbeel, Ron S. Weening, Dirk Roos · 1992 · Europe PMC (PubMed Central)
Innate host defense: Nox and Duox on phox's tail.
N. Grandvaux, Anton Soucy-Faulkner, K. Fink · 2007 · Biochimie
Activation of the NADPH oxidase in human fibroblasts by mechanical intrusion of a single cell with an ultramicroelectrode
Stéphane Arbault · 1997 · Carcinogenesis
Tumor Necrosis Factor–Related Apoptosis‐Inducing Ligand (TRAIL) Promotes Angiogenesis and Ischemia‐Induced Neovascularization Via NADPH Oxidase 4 (NOX4) and Nitric Oxide–Dependent Mechanisms
Belinda A. Di Bartolo, Siân Peta Cartland, Leonel Prado-Lourenço, Thomas S. Griffith, Carmine Gentile, J. Ravindran, Nor Saadah Md. Azahri, Thuan Thai, Amanda Wing Shee Yeung, Shane Ross Thomas et al. · 2015 · Journal of the American Heart Association
Inhibition of NADPH oxidase activation by synthetic peptides mapping within the carboxyl-terminal domain of small GTP-binding proteins. Lack of amino acid sequence specificity and importance of polybasic motif.
Gili Joseph, Yara Gorzalczany, Vasilij Koshkin, Edgar Pick · 1994 · Journal of Biological Chemistry
Glutathione is a Cofactor for H2O2-Mediated Stimulation of Ca2+-Induced Ca2+ Release in Cardiac Myocytes
Yuichiro Suzuki, Lars Nilausen Cleemann, Darrell R Abernethy, Martin Morad · 1998 · Free Radical Biology and Medicine
Angiogenic effects of stromal cell-derived factor-1 (SDF-1/CXCL12) variants in vitro and the in vivo expressions of CXCL12 variants and CXCR4 in human critical leg ischemia
Teik K. Ho, Janice C S Tsui, Shiwen Xu, Patricia Leoni, David Abraham, Daryll Baker · 2010 · Journal of Vascular Surgery
The NADPH Oxidase Nox4 mediates tumour angiogenesis
Valeska Helfinger, Nina Henke, Sabine Harenkamp, M. Walter, Jeremy Epah, Cornelia Penski, Michel Guy André Mittelbronn, Katrin Schröder · 2015 · Acta Physiologica
The Mechanism of Electron Donation to Molecular Oxygen by Phagocytic Cytochrome b558
Yasuhiro Isogai, Tetsutarō Iizuka, Yoshitsugu Shiro · 1995 · Journal of Biological Chemistry
Phosphorylation of threonine 154 in p40phox is an important physiological signal for activation of the neutrophil NADPH oxidase
Tamara A. M. Chessa, Karen E. Anderson, Yanhua Hu, Qingbo Xu, Oliver Rausch, Len Stephens, Phillip T. Hawkins · 2010 · Blood
Nox5 Forms a Functional Oligomer Mediated by Self-Association of Its Dehydrogenase Domain
Tsukasa Kawahara, Heather M. Jackson, Susan M. E. Smith, Paul D. Simpson, J. David Lambeth · 2011 · Biochemistry
Selective inactivation of NADPH oxidase 2 causes regression of vascularization and the size and stability of atherosclerotic plaques
I.M. Quesada, A. Lucero, Celina Amaya Sanchez, Daniel N. Meijles, Eugenia Cifuentes-Pagano, Patrick J. Pagano, C. Castro · 2015 · Atherosclerosis
Cloning and sequencing of the bovine flavocytochrome b subunit proteins, gp91-phox and p22-phox: comparison with other known flavocytochrome b sequences
Angela R. Davis, Patrice L. Mascolo, Peggy L Bunger, Karen M Sipes, Mark T. Quinn · 1998 · Journal of Leukocyte Biology
The intimate and controversial relationship between voltage‐gated proton channels and the phagocyte NADPH oxidase
Thomas E. DeCoursey · 2016 · Immunological Reviews
siRNA-mediated knock-down of NOX3: therapy for hearing loss?
Leonard P. Rybak, Debashree Mukherjea, Sarvesh Jajoo · 2012 · Cellular and Molecular Life Sciences
Regulation of NADPH Oxidase Activity in Phagocytes
Franck Debeurme, Antoine Picciocchi, Marie‐Claire Dagher · 2010 · Journal of Biological Chemistry
Nox3-Derived Superoxide in Cochleae Induces Sensorineural Hearing Loss
Hiroaki Mohri, Yuzuru Ninoyu, Hirofumi Sakaguchi, Shigeru Hirano, Naoaki Saito, Takehiko Ueyama · 2021 · Journal of Neuroscience
ACRATA: a novel electron transfer domain associated to apoptosis and cancer
Luis Sánchez‐Pulido, Ana Maria Rojas, Alfonso Valencia, Carlos Martínez‐A, Miguel Angel Andrade-Navarro · 2004 · BMC Cancer
Isoform-Specific Membrane Targeting Mechanism of Rac during FcγR-Mediated Phagocytosis: Positive Charge-Dependent and Independent Targeting Mechanism of Rac to the Phagosome
Ueyama, Takehiko, Eto, Mika, Kami, Keiichiro, Tatsuno, Toshihiko, Kobayashi, Toshihiro, Shirai, Yasuhito, Lennartz, Michelle R, Takeya, Ryu, Sumimoto, Hideki, Saito, Naoaki · 2005 · The Journal of Immunology
CRISPR/Cas9-mediated knockout of p22phox leads to loss of Nox1 and Nox4, but not Nox5 activity
Kim-Kristin Prior, Matthias S. Leisegang, Ivana Josipovic, Oliver Löwe, Ajay M. Shah, Norbert Weißmann, Katrin Schröder, Ralf Peter Brandes · 2016 · Redox Biology
Transforming growth factor‐β1 requires NADPH oxidase 4 for angiogenesisin vitroandin vivo
Hitesh Peshavariya, Elsa C. Chan, Guei‐Sheung Liu, Fan Jiang, Gregory James Dusting · 2014 · Journal of Cellular and Molecular Medicine
NADPH Oxidase and the Degeneration of Dopaminergic Neurons in Parkinsonian Mice
Marina S. Hernandes, Cecília C. Café-Mendes, Luiz Roberto Britto · 2013 · Oxidative Medicine and Cellular Longevity
Impaired NADPH oxidase activity in Rac2-deficient murine neutrophils does not result from defective translocation of p47phox and p67phox and can be rescued by exogenous arachidonic acid
Chaekyun Kim, Mary C. Dinauer · 2005 · Journal of Leukocyte Biology
p47 Molecular Activation for Assembly of the Neutrophil NADPH Oxidase Complex
Julien Marcoux, Petr Man, Isabelle Petit-Härtlein, Corinne Vivès, Éric Forest, Franck Fieschi · 2010 · Journal of Biological Chemistry
Cell Proliferation Induced by Reactive Oxygen Species Is Mediated via Mitogen-activated Protein Kinase in Chinese Hamster Lung Fibroblast (V79) Cells
Min‐Joon Han, Bu‐Yeo Kim, Sang-Oh Yoon, An‐Sik Chung · 2003 · Molecules and Cells
Gene expression and prognosis of NOX family members in gastric cancer
Xin You, Ming-zhe Ma, Guoxin Hou, Yumin Hu, Xi Shi · 2018 · OncoTargets and Therapy
The NADPH oxidases NOX4 and DUOX2 regulate cell cycle entry via a p53-dependent pathway
Annette E. Salmeen, B O Park, Tobias Meyer · 2010 · Oncogene
Cross-Talk between Receptor Tyrosine Kinases AXL and ERBB3 Regulates Invadopodia Formation in Melanoma Cells
Or‐Yam Revach, Oded Sandler, Yardena Samuels, Benjamin Geiger · 2019 · Cancer Research
Therapeutic Potential and Anti-Amyloidosis Mechanisms of Tert-Butylhydroquinone for Alzheimer's Disease
Hasina Akhter, Ashwini K. Katre, Ling Li, Xuebo Liu, Rui-Ming Liu · 2011 · Journal of Alzheimer s Disease
Absence of Proton Channels in COS-7 Cells Expressing Functional NADPH Oxidase Components
Deri Morgan, Vladimir V. Cherny, Marianne O. Price, Mary C. Dinauer, Thomas E. DeCoursey · 2002 · The Journal of General Physiology
Fused p47 and p67 Truncations Efficiently Reconstitute NADPH Oxidase with Higher Activity and Stability Than the Individual Components
Kentaro Ebisu, Teruaki Nagasawa, K Watanabe, Katsuko Kakinuma, Kei Miyano, MINORU N. TAMURA · 2001 · Journal of Biological Chemistry
Activation of the superoxide-producing phagocyte NADPH oxidase requires co-operation between the tandem SH3 domains of p47 phox in recognition of a polyproline type II helix and an adjacent α-helix of p22 phox
Ikuo Nobuhisa, Ryu Takeya, Kenji Ogura, Noriko Ueno, Daisuke Kohda, Fuyuhiko Inagaki, Hideki Sumimoto · 2006 · Biochemical Journal
Both hydrogen peroxide and transforming growth factor beta 1 contribute to endothelial Nox4 mediated angiogenesis in endothelial Nox4 transgenic mouse lines
Lili Chen, Xiuyun Hou, Jennifer M. Xiao, Junya Kuroda, Tetsuro Ago, Junichi Sadoshima, Richard Alan Cohen, Xiaoyong Tong · 2014 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
NADPH oxidase controls neutrophilic response to sterile inflammation in mice by regulating the IL-1α/G-CSF axis
Juhi Bagaitkar, Nancy K. Pech, Stoyan Ivanov, Anthony M. Austin, Melody Yue Zeng, Sabine Pallat, Guangming Huang, Gwendalyn J. Randolph, Mary C. Dinauer · 2015 · Blood