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Cited by 21Moringa oleifera research and applicationsPhytochemicals and Antioxidant ActivitiesMorinda citrifolia extract uses

Multifunctional Profiling of Moringa oleifera Leaf Extracts for Topical Application: A Comparative Study of Different Collection Time

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Baldisserotto, Anna, Barbari, Riccardo, Tupini, Chiara, Buzzi, Raissa, Durini, Elisa, Lampronti, Ilaria, Manfredini, Stefano, Baldini, Erika +1 more·2023·Antioxidants
DOI 10.3390/antiox12020411PMC PMC9952562
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Abstract

This research investigated plant extracts as a source of potential new actives in the nutritional, cosmetic, and pharmaceutical fields. Moringa oleifera, which is extensively known for its nutritional properties, has been investigated in this work by preparation, characterization, and evaluation of the antioxidant (FRAP, DPPH, ORAC, and PCL test), antifungal, photoprotective, and cytotoxicity profile against human melanoma Colo38 cell line of two different extracts (hydroalcoholic and methanolic) and one infusion of dry leaves collected from Paraguay in four distinct harvest times (February, March, April, and May 2017). The outcomes of this study highlight Moringa oleifera as a potential ally to counteract skin aging and oxidative stress, as indicated by the favorable antioxidant profile of the extracts and infusions of Paraguay, which was, in all cases, superior to that provided by the same plant species when collected from Senegal. Moreover, some samples were more efficient in preventing the photodegradation of UVA filter butyl methoxydibenzoylmethane (Avobenzone) compared to commercial filters, thus suggesting an interesting future role as natural additives in sunscreens.

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Authors
Baldisserotto, A., Barbari, R., Tupini, C., Buzzi, R., Durini, E., Lampronti, I., Manfredini, S., Baldini, E., & Vertuani, S.
Affiliations
University of Ferrara (IT)
Corresponding author
Baldisserotto, Anna
ORCID
Venue
Antioxidants
Publisher
MDPI AG
Published
2023-02-08
Volume
12
Issue
2
Pages
411
ISSN
2076-3921 (ISSN-L)
DOI
10.3390/antiox12020411
PMC
PMC9952562
OpenAlex
W4319597985
Cited by
21
References
51
Citations by year
2026: 4 · 2025: 8 · 2024: 7 · 2023: 2
FWCI
3.30
Type
journal article
Language
en
Open access
Licence
Locations
  • Antioxidants (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Institutional Research Information System University of Ferrara (University of Ferrara) (submittedVersion, other-oa)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
  • University of Ferrara (FAR 2020, FAR 2021, 2021)
  • COSMAST University of Ferrara (FAR 2020, FAR 2021, 2021)
  • Ambrosialab srl, Italy (FAR 2020, FAR 2021, 2021)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Moringa oleifera research and applications
  • Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
  • Health Sciences › Medicine › Complementary and alternative medicine › Morinda citrifolia extract uses
Keywords
Moringa oleifera, leaf extract, harvest time, antioxidant activity, antifungal activity, photoprotection, cytotoxicity, melanoma cell lines, hydroalcoholic extract, methanol extract, skin aging, oxidative stress, natural cosmetics

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