The DOI matches its Crossref record; 141 of the 141 references it cites were found in a registry or an index.
Hyaluronic Acid: Redefining Its Role
Open accessAbstract
The discovery of several unexpected complex biological roles of hyaluronic acid (HA) has promoted new research impetus for biologists and, the clinical interest in several fields of medicine, such as ophthalmology, articular pathologies, cutaneous repair, skin remodeling, vascular prosthesis, adipose tissue engineering, nerve reconstruction and cancer therapy. In addition, the great potential of HA in medicine has stimulated the interest of pharmaceutical companies which, by means of new technologies can produce HA and several new derivatives in order to increase both the residence time in a variety of human tissues and the anti-inflammatory properties. Minor chemical modifications of the molecule, such as the esterification with benzyl alcohol (Hyaff-11® biomaterials), have made possible the production of water-insoluble polymers that have been manufactured in various forms: membranes, gauzes, nonwoven meshes, gels, tubes. All these biomaterials are used as wound-covering, anti-adhesive devices and as scaffolds for tissue engineering, such as epidermis, dermis, micro-vascularized skin, cartilage and bone. In this review, the essential biological functions of HA and the applications of its derivatives for pharmaceutical and tissue regeneration purposes are reviewed.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
1 retracted
Tan, J., Wang, X., Su, X., Li, H., Shi, Y., Wang, L., & Ren, G.-S. (2011) · PLoS ONE · doi:10.1371/journal.pone.0022836 · Cited by 72
RetractedIsolation of Putative Progenitor Endothelial Cells for Angiogenesis
Asahara, T., Murohara, T., Sullivan, A., Silver, M., van der Zee, R., Li, T., Witzenbichler, B., Schatteman, G., & Isner, J. M. (1997) · Science · doi:10.1126/science.275.5302.964 · Cited by 8,725
Hyaluronan: its nature, distribution, functions and turnover.
Fraser, J. R. E., Laurent, T. C., & Laurent, U. B. G. (1997) · Journal of Internal Medicine · doi:10.1046/j.1365-2796.1997.00170.x · Cited by 2,031
Laurent, T. C., & Fraser, J. R. E. (1992) · The FASEB Journal · doi:10.1096/fasebj.6.7.1563592 · Cited by 1,880
Hyaluronan fragments: An information-rich system
Stern, R., Asari, A. A., & Sugahara, K. N. (2006) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2006.05.009 · Cited by 1,132
Hyaluronic acid based scaffolds for tissue engineering—A review
Collins, M. N., & Birkinshaw, C. (2013) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2012.10.028 · Cited by 1,092
Signaling Properties of Hyaluronan Receptors
Turley, E. A., Noble, P. W., & Bourguignon, L. Y. W. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.r100038200 · Cited by 1,041
THE POLYSACCHARIDE OF THE VITREOUS HUMOR
Meyer, K., & Palmer, J. W. (1934) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)75338-6 · Cited by 1,015
Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties
Itano, N., Sawai, T., Yoshida, M., Lenas, P., Yamada, Y., Imagawa, M., Shinomura, T., Hamaguchi, M., Yoshida, Y., Ohnuki, Y., et al. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.35.25085 · Cited by 901
Misra, S., Hascall, V. C., Markwald, R. R., & Ghatak, S. (2015) · Frontiers in Immunology · doi:10.3389/fimmu.2015.00201 · Cited by 830
Cited by
Advanced 3D-Printing Bioinks for Articular Cartilage Repair
Liang, Q., Ma, Y., Yao, X., & Wei, W. (2022) · International Journal of Bioprinting · doi:10.18063/ijb.v8i3.511 · Cited by 55
Metadata
- Authors
- Abatangelo, G., Vindigni, V., Avruscio, G., Pandis, L., & Brun, P.
- Venue
- Cells
- Publisher
- MDPI AG
- Published
- 2020-07-21
- Volume
- 9
- Issue
- 7
- Pages
- 1743
- ISSN
- 2073-4409 (ISSN-L)
- OpenAlex
- W3043828730
- Cited by
- 533
- References
- 141
- FWCI
- 21.27
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Hyaluronic Acid: Redefining Its Role. https://app.cochat.ai/papers/10.3390/cells9071743
- The paper
- Abatangelo, G., Vindigni, V., Avruscio, G., Pandis, L., & Brun, P. (2020). Hyaluronic Acid: Redefining Its Role. Cells. https://doi.org/10.3390/cells9071743
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
