The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Inflammation in Chronic Wounds
Open accessAbstract
Non-healing chronic wounds present a major biological, psychological, social, and financial burden on both individual patients and the broader health system. Pathologically extensive inflammation plays a major role in the disruption of the normal healing cascade. The causes of chronic wounds (venous, arterial, pressure, and diabetic ulcers) can be examined through a juxtaposition of normal healing and the rogue inflammatory response created by the common components within chronic wounds (ageing, hypoxia, ischaemia-reperfusion injury, and bacterial colonisation). Wound bed care through debridement, dressings, and antibiotics currently form the basic mode of treatment. Despite recent setbacks, pharmaceutical adjuncts form an interesting area of research.
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Cites
Gurtner, G. C., Werner, S., Barrandon, Y., & Longaker, M. T. (2008) · Nature · doi:10.1038/nature07039 · Cited by 6,542
Inflammation in Wound Repair: Molecular and Cellular Mechanisms
Eming, S. A., Krieg, T., & Davidson, J. M. (2007) · Journal of Investigative Dermatology · doi:10.1038/sj.jid.5700701 · Cited by 2,429
Reinke, J. M., & Sorg, H. (2012) · European Surgical Research · doi:10.1159/000339613 · Cited by 1,898
The molecular biology of chronic wounds and delayed healing in diabetes
Blakytny, R., & Jude, E. (2006) · Diabetic Medicine · doi:10.1111/j.1464-5491.2006.01773.x · Cited by 632
Interactions of cytokines, growth factors, and proteases in acute and chronic wounds
Mast, B. A., & Schultz, G. S. (1996) · Wound Repair and Regeneration · doi:10.1046/j.1524-475x.1996.40404.x · Cited by 598 · cited 1×
“Both neutrophils and activated macrophages also produce pro-inflammatory cytokines such as IL-1β and TNF-α that not only increase MMP production but also reduce tissue inhibitors of MMPs (TIMPs); this imbalance augments degradation of the ECM, impairs cell migration, and reduces fibroblast proliferation and collagen s…”
BackgroundBiofilms and Inflammation in Chronic Wounds
Zhao, G., Usui, M. L., Lippman, S. I., James, G. A., Stewart, P. S., Fleckman, P., & Olerud, J. E. (2013) · Advances in Wound Care · doi:10.1089/wound.2012.0381 · Cited by 448 · cited 1×
“Microbial cells are embedded in a secreted polymer matrix, which provides an optimal environment for bacteria to evade host immune response and antibiotic action [67].”
BackgroundAshcroft, G. S., Mills, S. J., & Ashworth, J. J. (2002) · Biogerontology · doi:10.1023/a:1021399228395 · Cited by 309
Cell-matrix interactions in dermal repair and scarring
Eckes, B., Nischt, R., & Krieg, T. (2010) · Fibrogenesis & Tissue Repair · doi:10.1186/1755-1536-3-4 · Cited by 205
Uchiba, M., Okajima, K., Oike, Y., Ito, Y., Fukudome, K., Isobe, H., & Suda, T. (2004) · Circulation Research · doi:10.1161/01.res.0000133680.87668.fa · Cited by 162
Inflammation in surgical wound healing: Friend or foe?
Szpaderska, A. M., & DiPietro, L. A. (2005) · Surgery · doi:10.1016/j.surg.2005.01.006 · Cited by 96
Cited by
Rational Design of Immunomodulatory Hydrogels for Chronic Wound Healing
Kharaziha, M., Baidya, A., & Annabi, N. (2021) · Advanced Materials · doi:10.1002/adma.202100176 · Cited by 721
Exosome‐Guided Phenotypic Switch of M1 to M2 Macrophages for Cutaneous Wound Healing
Kim, H., Wang, S. Y., Kwak, G., Yang, Y., Kwon, I. C., & Kim, S. H. (2019) · Advanced Science · doi:10.1002/advs.201900513 · Cited by 542
A review on nanoparticle based treatment for wound healing
Rajendran, N. K., Kumar, S. S. D., Houreld, N. N., & Abrahamse, H. (2018) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2018.01.009 · Cited by 389
Chronic wounds: Current status, available strategies and emerging therapeutic solutions
Las Heras, K., Igartua, M., Santos-Vizcaino, E., & Hernandez, R. M. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.09.039 · Cited by 370
Silk biomaterials in wound healing and skin regeneration therapeutics: From bench to bedside
Chouhan, D., & Mandal, B. B. (2020) · Acta Biomaterialia · doi:10.1016/j.actbio.2019.11.050 · Cited by 348
Metadata
- Authors
- Zhao, R., Liang, H., Clarke, E., Jackson, C., & Xue, M.
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2016-12-11
- Volume
- 17
- Issue
- 12
- Pages
- 2085
- ISSN
- 1422-0067 (ISSN-L)
- OpenAlex
- W2567221680
- Cited by
- 1,180
- References
- 10
- FWCI
- 28.49
- Type
- journal article
- Language
- en
- Open access
- gold
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- Zhao, R., Liang, H., Clarke, E., Jackson, C., & Xue, M. (2016). Inflammation in Chronic Wounds. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms17122085
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
