PGC-1α protects RPE cells of the aging retina against oxidative stress-induced degeneration through the regulation of senescence and mitochondrial quality control. The significance for AMD pathogenesis

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Items 101–112 of 112

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3. Investigation of the effect of TNF-α on damage to retinal pigment epithelial cells in age-related macular degeneration
   Н. В. Малачкова, Mohammad Mashhour Mohammad Masa’deh · 2022 · Reports of Morphology
4. Evidence of retinal arteriolar narrowing in patients with autosomal-dominant polycystic kidney disease
   Maria Pietrzak-Nowacka, Renata Lejkowska, Miłosz Piotr Kawa, Zofia Ulańczyk, Krzysztof Safranow, Barbara Nowacka, Karolina Podborączyńska‐Jodko, Wojciech Lubiński, Kazimierz Ciechanowski, Bogusław Machaliński et al. · 2022 · Postępy Higieny i Medycyny Doświadczalnej
5. Characterization and contribution of RPE senescence to Age-related macular degeneration in Tnfrsf10 knock out mice
   Iori Wada, Kenichiro Mori, Parameswaran Gangadharan Sreekumar, Rui Ji, Christine K. Spee, Elise Hong, Keijiro Ishikawa, Koh‐Hei Sonoda, Ram Kannan · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
6. Five-year post-onset visual acuity trajectories in Japanese Leber hereditary optic neuropathy: a longitudinal analysis by age, sex, and mtDNA mutation
   Yasuyuki Takai, Akiko Yamagami, Mayumi Iwasa, Kenji Inoue, Ryoma Yasumoto, Hitoshi Ishikawa, Masato Wakakura · 2026 · Canadian Journal of Ophthalmology
7. Peroxisomal dynamics in degenerative retinopathies: implications of retinal lipid metabolism and therapeutic potential
   Sa Sun, Mengli Sun, Zhihui Feng, Xiaosu Wang, Bizhu Zhao, Kexin Wang, Yiwen Wang, Jiehao Zhang, Shenao Ding, Chengzhi Zhang et al. · 2026 · Experimental Eye Research
8. Effects of early-life and chronic exposure to dietary advanced glycation end-products on chronic low-grade inflammation and age-associated disorders
   Matheus Thomaz Nogueira Silva Lima · 2023
9. Modulation of Iron-Induced Glucose Metabolic Reprogramming Alleviates Retinal Pigment Epithelial Cell Senescence
   Zhenzhen Zhao, Qingjian Ou, Jincheng Zhu, Zixu He, Yanrong Yang, J Jiang, Q Wang, Yi Zhou, Ying Liu, Xiaoman Zhu et al. · 2026 · Investigative Ophthalmology & Visual Science
10. Physalin A Restores Redox and Mitochondrial Homeostasis to Protect against Diabetic Retinopathy
    Yan-Ru Xiao, Yow‐Wen Hsieh, Wei‐Yong Lin, YU-SHENG HSIEH, Wei-Cheng Jiang, Pei‐Ying Pai, Yueh-Hsiung Kuo, Dah-Yuu Lu, Yu‐Jung Lin, Wen‐Tsong Hsieh · 2026 · Antioxidants and Redox Signaling
11. Characterization of mitochondrial dysfunction induced by BAX trigger site activator 1 in the ARPE-19 retinal pigment epithelial cell model
    Toshihide Kashihara, Yuka Akiyama, Akane Morita, Saori Deguchi, Ryosuke Odaka, Tsutomu Nakahara · 2026 · European Journal of Pharmacology
12. Physiological Hypoxia and Pharmacological HIF Stabilization Induce Distinct but Overlapping Responses in Retinal Pigment Epithelial Cells
    Tamás Gáll, Dávid Pethő, Szilárd Póliska, József Balla, György Balla · 2026 · Pharmaceuticals