Regulation of the p53 Family Proteins by the Ubiquitin Proteasomal Pathway

Cites (262)

Items 201–254 of 254

1. Pirh2 E3 Ubiquitin Ligase Modulates Keratinocyte Differentiation through p63
   Yong-Sam Jung, Yingjuan Qian, Wensheng Yan, Xinbin Chen · 2012 · Journal of Investigative Dermatology
2. Ubiquitin ligase TRIM71 suppresses ovarian tumorigenesis by degrading mutant p53
   Yajie Chen, Qian Hao, Jieqiong Wang, Jiajia Li, Canhua Huang, Yu Zhang, Xiaohua Wu, Hua Lu, Xiang Yu Zhou · 2019 · Cell Death and Disease
3. Mdm2 and Tumorigenesis: Evolving Theories and Unsolved Mysteries
   E. Senturk, James J. Manfredi · 2012 · Genes & Cancer
4. Over-expression of human UREB1 in colorectal cancer: HECT domain of human UREB1 inhibits the activity of tumor suppressor p53 protein
   Sun Young Yoon, Younghee Lee, Joo Heon Kim, An‐Sik Chung, Joung Hyuck Joo, Chang-Nam Kim, Nam-Soon Kim, In Seong Choe, Jae Wha Kim · 2004 · Biochemical and Biophysical Research Communications
5. The topoisomerase I- and p53-binding protein topors is differentially expressed in normal and malignant human tissues and may function as a tumor suppressor
   Ahamed Saleem, Jayeeta Dutta, Diptee Malegaonkar, Farheena Rasheed, Zeshaan A. Rasheed, Rajeev Rajendra, Henderson Marshall, Minje Luo, Honghua Li, Eric H. Rubin · 2004 · Oncogene
6. Mechanisms of Mutant p53 Stabilization in Cancer
   Rebecca A. Frum, Steven R. Grossman · 2014 · Sub-cellular biochemistry/Subcellular biochemistry
7. Tumour‐promoting activity of altered WWP1 expression in breast cancer and its utility as a prognostic indicator
   NS Nguyen Huu, W. David J. Ryder, Nikolajs Zeps, Marzena Flasza, Maybo Chiu, A M Hanby, Richard Poulsom, Robert B. Clarke, Martín Baron · 2008 · The Journal of Pathology
8. UBE4B levels are correlated with clinical outcomes in neuroblastoma patients and with altered neuroblastoma cell proliferation and sensitivity to epidermal growth factor receptor inhibitors
   Peter E. Zage, Natalie Sirisaengtaksin, Yin Liu, Monica Gireud, Brandon S Brown, Shana L. Palla, Kristen N. Richards, Dennis P.M. Hughes, Andrew J. Bean · 2012 · Cancer
9. Tissue‐specific and age‐dependent effects of global Mdm2 loss
   Yun Zhang, Shunbin Xiong, Qin Li, Sophia Hu, Mehrnoosh Tashakori, Carolyn Van Pelt, Mingjian James You, Laura R. Pageon, Guillermina Lozano · 2014 · The Journal of Pathology
10. The p73 Tumor Suppressor Is Targeted by Pirh2 RING Finger E3 Ubiquitin Ligase for the Proteasome-dependent Degradation
    Yong-Sam Jung, Yingjuan Qian, Xinbin Chen · 2011 · Journal of Biological Chemistry
11. The E3 ubiquitin ligase WWP1 regulates ΔNp63-dependent transcription through Lys63 linkages
    Angelo Peschiaroli, Flavia Scialpi, Francesca Bernassola, El Said El Sherbini, Gerry Melino · 2010 · Biochemical and Biophysical Research Communications
12. MDM2 mediates p73 ubiquitination: a new molecular mechanism for suppression of p73 function
    Hong Wu, Roger P. Leng · 2015 · Oncotarget
13. Pirh2
    Marie‐jo Halaby, Razqallah Hakem, Anne Hakem · 2013 · Cell Cycle
14. Control of Genomic Instability and Epithelial Tumor Development by the p53-Fbxw7/Cdc4 Pathway
    Jesús Pérez‐Losada, Jian‐Hua Mao, Allan Balmain · 2005 · Cancer Research
15. A cluster of genes located in 1p36 are down-regulated in neuroblastomas with poor prognosis, but not due to CpG island methylation.
    Helena Carén, Katarina Ejeskär, Susanne M. Fransson, Luke B. Hesson, Farida Latif, Rose‐Marie Sjöberg, Cecilia C. Krona, Tommy Martinsson · 2005 · Molecular Cancer
16. Pirh2, a Ubiquitin E3 Ligase, Inhibits p73 Transcriptional Activity by Promoting Its Ubiquitination
    Hong Wu, Zeinab Abou, Elsa Renee Flores, Roger P. Leng · 2011 · Molecular Cancer Research
17. Early evidence for the role of TRIM29 in multiple cancer models
    Shigetsugu Hatakeyama · 2016 · Expert Opinion on Therapeutic Targets
18. SCFJFK is a bona fide E3 ligase for ING4 and a potent promoter of the angiogenesis and metastasis of breast cancer
    Ruorong Yan, Lin He, Zhongwu Li, Xiao Han, Jing Liang, Wenzhe Si, Zhe Chen, Lei Li, Guojia Xie, Wanjin Li et al. · 2015 · Genes & Development
19. Differential response between the p53 ubiquitin–protein ligases Pirh2 and MdM2 following DNA damage in human cancer cells
    Wenrui Duan, Li Gao, Xin Wu, Yang Zhang, Gregory A. Otterson, Miguel Angel Villalona-Calero · 2006 · Experimental Cell Research
20. Widespread Overexpression of Epitope-Tagged Mdm4 Does Not Accelerate Tumor Formation In Vivo
    De Clercq, Sarah, Gembarska, Agnieszka, Denecker, Geertrui, Maetens, Marion, Naessens, Michael, Haigh, Katharina, Haigh, Jody J., Marine, Jean-Christophe · 2010 · Molecular and Cellular Biology
21. The Ubiquitin Ligase COP1 Promotes Glioma Cell Proliferation by Preferentially Downregulating Tumor Suppressor p53
    Shenshan Zou, Yufu Zhu, Bin Wang, Fengyuan Qian, Xiang Zhang, Lei Wang, Chunling Fu, Hanmo Bao, Manyi Xie, Shangfeng Gao et al. · 2016 · Molecular Neurobiology
22. Regulatory feedback loop between TP73 and TRIM32
    Laura González-Cano, Anna‐Lena Hillje, Sandra Fuertes-Álvarez, Margarita M. Marqués, A Blanch, R W Ian, Meredith S. Irwin, Jens Christian Schwamborn, María C. Marín · 2013 · Cell Death and Disease
23. E4F1 deficiency results in oxidative stress–mediated cell death of leukemic cells
    Elodie Hatchi, Geneviève Rodier, Matthieu Lacroix, Julie Caramel, Olivier Kirsh, Chantal Jacquet, Emilie Schrepfer, Sylviane Lagarrigue, Laetitia Karine Linares, Gwendaline Lledo et al. · 2011 · The Journal of Experimental Medicine
24. WWP2-WWP1 Ubiquitin Ligase Complex Coordinated by PPM1G Maintains the Balance between Cellular p73 and ΔNp73 Levels
    Neelam Chaudhary, Subbareddy Maddika · 2014 · Molecular and Cellular Biology
25. Huwe1 Regulates the Establishment and Maintenance of Spermatogonia by Suppressing DNA Damage Response
    Kin Lam Fok, Rohini Bose, Kai Sheng, Ching-Wen Chang, Mira Katz-Egorov, Martine Culty, Sicheng Su, Ming Jen Yang, Ye Chun Ruan, Hsiao Chang Chan et al. · 2017 · Endocrinology
26. Regulation of p53 Level by UBE4B in Breast Cancer
    Ying Zhang, Yanrong Lv, Yongyang Zhang, Haidong Gao · 2014 · PLoS ONE
27. Characterization of ARF-BP1/HUWE1 Interactions with CTCF, MYC, ARF and p53 in MYC-Driven B Cell Neoplasms
    Chen‐Feng Qi, Yongsoo Kim, Xiang Shao, Ziedulla Abdullaev, Ted Albert Torrey, Siegfried Janz, Alexander L. Kovalchuk, Jiafang Sun, Delin Chen, William Chi Shing Cho et al. · 2012 · International Journal of Molecular Sciences
28. High Level of COP1 Expression is Associated with Poor Prognosis in Primary Gastric Cancer
    Yuan-fang Li, Dandan Wang, Bai-wei Zhao, Wei Wang, Chun-yu Huang, Yong-ming Chen, Yan Zheng, Rajiv Prasad Keshari, Jian‐Chuan Xia, Zhi-Wei Zhou · 2012 · International Journal of Biological Sciences
29. Expression of Pirh2, a p27Kip1 ubiquitin ligase, in hepatocellular carcinoma: correlation with p27Kip1 and cell proliferation
    Xiaodong Huang, Xiaoli Qian, Chun Cheng, Song He, Linlin Sun, Qing Ke, Li Zhang, Xia Pan, Fei He, Qiuhong Wang et al. · 2011 · Human Pathology
30. CHIP Is an Essential Determinant of Neuronal Mitochondrial Stress Signaling
    Amy M. Palubinsky, Jeannette N. Stankowski, Alixandra C. Kale, Simona G. Codreanu, Robert J. Singer, Daniel C. Liebler, Gregg D. Stanwood, BethAnn McLaughlin · 2015 · Antioxidants and Redox Signaling
31. Good COP1 or bad COP1? In vivo veritas
    Wenyi Wei, William G. Kaelin · 2011 · Journal of Clinical Investigation
32. Trim32 Deficiency Enhances Th2 Immunity and Predisposes to Features of Atopic Dermatitis
    Yuangang Liu, Zhiping Wang, Rachel De La Torre, Ashley N. Barling, Takahiro Tsujikawa, Noah I. Hornick, Jon M. Hanifin, Eric Lawrence Simpson, Yun Wang, Emily Swanzey et al. · 2016 · Journal of Investigative Dermatology
33. Deficiency of the dual ubiquitin/SUMO ligase Topors results in genetic instability and an increased rate of malignancy in mice
    Henderson Marshall, Mantu Bhaumik, Hana Aviv, Dirk F. Moore, Ming Yao, Jayeeta Dutta, Hussein M. Rahim, Murugesan K. Gounder, Shridar Ganesan, Ahamed Saleem et al. · 2010 · BMC Molecular Biology
34. Expression of LUN gene that encodes a novel RING finger protein is correlated with development and progression of non-small cell lung cancer
    Hiroki Oyanagi, Kazumasa Takenaka, Shinya Ishikawa, Yozo Kawano, Yoshifumi Adachi, Kunihiro Ueda, Hiromi Wada, Fumihiro Tanaka · 2004 · Lung Cancer
35. Abrogation of FBW7α-dependent p53 degradation enhances p53’s function as a tumor suppressor
    Vivek Tripathi, Ekjot Kaur, Suhas S. Kharat, Mansoor Hussain, Arun Prasath Damodaran, Swati Kulshrestha, Sagar Sengupta · 2019 · Journal of Biological Chemistry
36. Structural convergence of unstructured p53 family transactivation domains in MDM2 recognition
    Jae‐Sun Shin, Ji‐Hyang Ha, Dong-Hwa Lee, Kyoung‐Seok Ryu, Kwang‐Hee Bae, Byoung Chul Park, Sung Goo Park, Gwan‐Su Yi, Seung‐Wook Chi · 2015 · Cell Cycle
37. MDM2 promotes the proteasomal degradation of p73 through the interaction with Itch in HeLa cells
    Natsumi Kubo, Rintaro Okoshi, Kumiko Nakashima, Osamu Shimozato, Akira Nakagawara, Toshinori Ozaki · 2010 · Biochemical and Biophysical Research Communications
38. Ubiquitin ligase CHIP functions as an oncogene and activates the AKT signaling pathway in prostate cancer
    Li Cheng, Jin Zang, Hanjue Dai, Feng Li, Feng Guo · 2018 · International Journal of Oncology
39. Mutant p53 and MDM2 in Cancer
    Swati Palit Deb, Sumitra Deb · 2014 · Sub-cellular biochemistry/Subcellular biochemistry
40. Mdm2 overexpression and p73 loss exacerbate genomic instability and dampen apoptosis, resulting in B-cell lymphoma
    Maurisa F. Riley, Mingjian James You, Asha S. Multani, Guillermina Lozano · 2015 · Oncogene
41. HUWE1 upregulation has tumor suppressive effect in human prostate cancer cell lines through c-Myc
    Hua-Wei Qu, Hui Liu, Jin Yang, Zilian Cui, Gang Han · 2018 · Biomedicine & Pharmacotherapy
42. Targeting Trim69 alleviates high fat diet (HFD)-induced hippocampal injury in mice by inhibiting apoptosis and inflammation through ASK1 inactivation
    Linjuan Li, Jun-Chen Zheng, Rui Kang, Jianqun Yan · 2019 · Biochemical and Biophysical Research Communications
43. Dichotomous role of pancreatic HUWE1/MULE/ARF-BP1 in modulating beta cell apoptosis in mice under physiological and genotoxic conditions
    Linyuan Wang, Cynthia T. Luk, Stephanie A. Schroer, Alannah M. Smith, Li Ping Xie, Erica P. Cai, Herbert Y. Gaisano, Patrick E. MacDonald, Zhenyue Hao, Tak W. Mak et al. · 2014 · Diabetologia
44. HUWE1 plays important role in mouse preimplantation embryo development and the dysregulation is associated with poor embryo development in humans
    L. J. Chen, W. M. Xu, Mei Yang, K. Wang, Y. Chen, X. J. Huang, Q. H. · 2016 · Scientific Reports
45. Pir2/Rnf144b is a potential endometrial cancer biomarker that promotes cell proliferation
    Qing Zhou, Sahar Eldakhakhny, Franco Conforti, Emma Jayne Crosbie, Gerry Melino, Berna S. Sayan · 2018 · Cell Death and Disease
46. CARP2 deficiency does not alter induction of NF-κB by TNFα
    Afsar U. Ahmed, Maryline Moulin, Franck Coumailleau, Wendy Wei-Lynn Wong, Maria Miasari, Holly Carter, John Silke, Michel Cohen‐Tannoudji, James Edward Vince, David Lawrence Vaux · 2009 · Current Biology
47. Knockdown of WWP1 inhibits growth and invasion, but induces apoptosis of osteosarcoma cells.
    Zhong Wu, Pengfei Zan, Shaohua Li, Jie Liu, Jianguang Wang, Dong Chen, Hua Wang, Yongqiang Qian, Linjie Luo, Xiang Huang · 2015 · PubMed Central
48. Inhibition of ITCH Suppresses Proliferation and Induces Apoptosis of Lung Cancer Cells
    Pengfei Li, Qi-Gang Zhang · 2018 · Cellular Physiology and Biochemistry
49. p53 and FBXW7: Sometimes Two Guardians Are Worse than One
    María Galindo‐Moreno, Servando Giráldez, M. Cristina Limón‐Mortés, Alejandro Belmonte‐Fernández, Carmen Sáez, Miguel Á. Japón, María Tortolero, Francisco Romero · 2020 · Cancers
50. The C-terminal SAM domain of p73 binds to the N terminus of MDM2
    José L. Neira, Clara Díaz-García, Manuel J. E. PRIETO, Ana Coutinho · 2019 · Biochimica et Biophysica Acta (BBA) - General Subjects
51. Ubiquitination-dependent degradation of p73 by the mitochondrial E3 ubiquitin ligase Hades
    Bumki Min, Jiwon Ryu, Seung‐Wook Chi, Gwan‐Su Yi · 2015 · Biochemical and Biophysical Research Communications
52. The E3 ligase Itch knockout mice show hyperproliferation and wound healing alteration
    Alessandro Giamboi Miraglia, Francesca Cianfarani, Caterina Cattani, Anna Maria Lena, Valeria Serra, Elena Campione, Alessandro Terrinoni, Giovanna Zambruno, Teresa Odorisio, Nicola Di Daniele et al. · 2015 · FEBS Journal
53. High expression of constitutive photomorphogenic 1 (COP1) is associated with poor prognosis in bladder cancer
    Jianlong Li, Longwang Wang, Ruihai Xiao, Qiufeng Pan, Hongwei Huang, Renrui Kuang · 2016 · Tumor Biology
54. A Novel Protein Interaction between Nucleotide Binding Domain of Hsp70 and p53 Motif
    Asita Elengoe, Mohammed Abu Naser, Salehhuddin Hamdan · 2015 · International Journal of Genomics