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Cited by 336

The DOI matches its Crossref record; 113 of the 113 references it cites were found in a registry or an index.

Recent Updates of Transarterial Chemoembolilzation in Hepatocellular Carcinoma

Open access
Chang, Young, Jeong, Soung Won, Young Jang, Jae, Jae Kim, Yong·2020·International Journal of Molecular Sciences
DOI 10.3390/ijms21218165
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Abstract

Transarterial chemoembolization (TACE) is a standard treatment for intermediate-stage hepatocellular carcinoma (HCC). In this review, we summarize recent updates on the use of TACE for HCC. TACE can be performed using two techniques; conventional TACE (cTACE) and drug-eluting beads using TACE (DEB-TACE). The anti-tumor effect of the two has been reported to be similar; however, DEB-TACE carries a higher risk of hepatic artery and biliary injuries and a relatively lower risk of post-procedural pain than cTACE. TACE can be used for early stage HCC if other curative treatments are not feasible or as a neoadjuvant treatment before liver transplantation. TACE can also be considered for selected patients with limited portal vein thrombosis and preserved liver function. When deciding to repeat TACE, the ART (Assessment for Retreatment with TACE) score and ABCR (AFP, BCLC, Child-Pugh, and Response) score can guide the decision process, and TACE refractoriness needs to be considered. Studies on the combination therapy of TACE with other treatment modalities, such as local ablation, radiation therapy, or systemic therapy, have been actively conducted and are still ongoing. Recently, new prognostic models, including analysis of the neutrophil-lymphocyte ratio, radiomics, and deep learning, have been developed to help predict survival after TACE.

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Metadata

Authors
Chang, Y., Jeong, S. W., Young Jang, J., & Jae Kim, Y.
Venue
International Journal of Molecular Sciences
Publisher
MDPI AG
Published
2020-10-31
Volume
21
Issue
21
Pages
8165
ISSN
1422-0067 (ISSN-L)
DOI
10.3390/ijms21218165
OpenAlex
W3096663029
Cited by
336
References
113
FWCI
16.98
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Recent Updates of Transarterial Chemoembolilzation in Hepatocellular Carcinoma. https://app.cochat.ai/papers/10.3390/ijms21218165
The paper
Chang, Y., Jeong, S. W., Young Jang, J., & Jae Kim, Y. (2020). Recent Updates of Transarterial Chemoembolilzation in Hepatocellular Carcinoma. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms21218165

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.