Enhanced Aggression, Reduced Self-Grooming Behavior and Altered 5-HT Regulation in the Frontal Cortex in Mice Lacking Trace Amine-Associated Receptor 1 (TAAR1)

Zhukov, Ilya S.; Karpova, Inessa V.; Krotova, Nataliya A.; Tissen, Ilya Y.; Demin, Konstantin A.; Shabanov, Petr D.; Budygin, Evgeny A.; Kalueff, Allan V.; Gainetdinov, Raul R.

doi:10.3390/ijms232214066

Enhanced Aggression, Reduced Self-Grooming Behavior and Altered 5-HT Regulation in the Frontal Cortex in Mice Lacking Trace Amine-Associated Receptor 1 (TAAR1)

The Trace Amine-Associated Receptor 1 (TAAR1) is one of the six functional receptors belonging to the family of monoamine-related G protein-coupled receptors (TAAR1-TAAR9) found in humans. However, the exact biological mechanisms of TAAR1 central and peripheral action remain to be fully understoo…