Physical Activity and Diet Quality: Effects on Cardiovascular Morbidity in Women with Turner Syndrome—Results from an Online Patient Survey
Open accessAbstract
Turner syndrome (TS) is a rare chromosomal disease with increased cardiovascular morbidity and mortality. The aim of this study was to investigate the influence of physical activity and diet quality on cardiovascular morbidity in German TS women. An anonymous online questionnaire was established. The questionnaire was based on the 2020 WHO recommendations on physical activity and sedentary behaviour and included the 14-Item Mediterranean Diet Assessment Tool. In addition, TS patients were asked about existing cardiovascular conditions. In total, 83 TS women were included in the final analysis. The achievement of <600 Metabolic Equivalent-minutes per week for recreational activities was significantly associated with the presence of arterial hypertension (p = 0.006). High adherence to the Mediterranean diet was achieved by only 20.5% of TS subjects and tended to be inversely associated with the presence of lipid metabolism disorders (p = 0.063). Only 37.3% of TS participants received nutritional counselling. Given the increased cardiovascular risk, specific counselling for lifestyle optimisation may play an important role in the management of TS. Further studies are required to evaluate the effects of regular aerobic physical training and different nutritional programs on cardiovascular morbidity in TS.
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In recent surveys, a sedentary lifestyle was reported by more than half of children and adults with TS and was associated with arterial hypertension.
“In recent surveys, a sedentary lifestyle was reported by more than half of children and adults with TS and was associated with arterial hypertension.496-498”
From Clinical practice guidelines for the care of girls and women with Turner syndrome. (2024) · cites this paper as [498]
Another study found only 37% of TS adults had received nutrition counseling and only one fifth of these were adherent to the recommended Mediterranean diet which is believed to support cardiometabolic health.
“Another study found only 37% of TS adults had received nutrition counseling and only one fifth of these were adherent to the recommended Mediterranean diet which is believed to support cardiometabolic health.498”
From Clinical practice guidelines for the care of girls and women with Turner syndrome. (2024) · cites this paper as [498]
The available literature shows that girls and women with TS do not meet current general recommendations for physical activity, which is concerning because less physical activity has been associated with excess weight gain and hypertension in adults with TS.
“The available literature shows that girls and women with TS do not meet current general recommendations for physical activity,357,455,496-498 which is concerning because less physical activity has been associated with excess weight gain and hypertension in adults with TS.”
From Clinical practice guidelines for the care of girls and women with Turner syndrome. (2024) · cites this paper as [498]
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References 32 · Cited by 6
Research works printed but not linked: 3
- [4]Mitchell G.F. Hwang S.-J. Vasan R.S. Larson M.G. Pencina M.J. Hamburg N.M. Vita J.A. Levy D. Benjamin E.J. Arterial stiffness and cardiovascular events: The Framingham Heart Study Circulation 2010 121 505 511 10.1161/CIRCULATIONAHA.109.886655 20083680 PMC2836717 · DOI · Paper page
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- [24]Mensink G.B.M. Schienkiewitz A. Haftenberger M. Lampert T. Ziese T. Scheidt-Nave C. Übergewicht und Adipositas in Deutschland: Ergebnisse der Studie zur Gesundheit Erwachsener in Deutschland (DEGS1) Bundesgesundheitsblatt Gesundh. Gesundh. 2013 56 786 794 10.1007/s00103-012-1656-3 23703499 · DOI
- Authors
- Arnold, L., Bacova, M., Dalla-Pozza, R., Haas, N. A., & Oberhoffer, F. S.
- Affiliations
- Ludwig-Maximilians-Universität München (DE)
- Department of Pediatric Cardiology and Intensive Care, Medical Hospital of the University of Munich, Ludwig Maximilians University Munich, 81377 Munich, Germany
- Corresponding author
- Oberhoffer, Felix Sebastian
- Venue
- Journal of Clinical Medicine
- Publisher
- MDPI AG
- Published
- 2021-12-29
- Volume
- 11
- Issue
- 1
- Pages
- 167
- ISSN
- 2077-0383 (ISSN-L)
- PMC
- PMC8745768
- OpenAlex
- W4200605369
- Cited by
- 6
- References
- 32
- Citations by year
- 2025: 1 · 2024: 2 · 2022: 3
- FWCI
- 0.71
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Journal of Clinical Medicine (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- mediaTUM (Technical University of Munich) (submittedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Keywords
- Turner syndrome, cardiovascular morbidity, physical activity, diet quality, Mediterranean diet, hypertension, lipid metabolism disorders, nutrition counseling, sedentary behavior, women, lifestyle counseling
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