The DOI matches its Crossref record; 64 of the 64 references it cites were found in a registry or an index.
Probiotic Potential of Yeasts Isolated from Fermented Beverages: Assessment of Antagonistic Strategies Against Salmonella enterica Serovar Enteritidis
Abstract
Global concern about pathogenic resistance to antibiotics is prompting interest in probiotics as a strategy to prevent or inhibit infections. Fermented beverages are promising sources of probiotic yeasts. This study aimed to evaluate the antagonistic effects of Kluyveromyces marxianus, Wickerhamomyces anomalus, and Pichia manshurica strains from kefir and wine against Salmonella enterica serovar Enteritidis in intestinal epithelial cells. The ability of these yeasts to adhere to Caco-2/TC-7 cells was evaluated, as well as their influence on the ability of Salmonella to associate and invade these cells. The behavior of the pathogen was analyzed by (a) incubation of enterocytes with yeast before adding Salmonella, (b) co-incubation of Salmonella with yeast before contact with the enterocytes, and (c) incubation of Salmonella with yeast metabolites before contact with enterocytes. All yeast strains demonstrated adherence to Caco-2/TC-7 cells (33–100%) and effectively inhibited Salmonella invasion. Among the treatments, co-culture showed the greatest effect, reducing Salmonella association and invasion by more than 50%. Additionally, these yeasts modulated the epithelial immune response, significantly decreasing CCL20-driven luminescence by 60–81% (p < 0.0001). These results highlight the potential of yeasts from fermented beverages as probiotics to counteract Salmonella infections, offering a promising alternative in the fight against antibiotic resistance.
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Cites
Hill (2014) · doi:10.1038/nrgastro.2014.66 · Cited by 9,592
Gut inflammation provides a respiratory electron acceptor for Salmonella
Winter, S. E., Thiennimitr, P., Winter, M. G., Butler, B. P., Huseby, D. L., Crawford, R. W., Russell, J. M., Bevins, C. L., Adams, L. G., Tsolis, R. M., et al. (2010) · Nature · doi:10.1038/nature09415 · Cited by 1,290
Host-Derived Nitrate Boosts Growth of E. coli in the Inflamed Gut
Winter, S. E., Winter, M. G., Xavier, M. N., Thiennimitr, P., Poon, V., Keestra, A. M., Laughlin, R. C., Gomez, G., Wu, J., Lawhon, S. D., et al. (2013) · Science · doi:10.1126/science.1232467 · Cited by 1,019
Esteve-Zarzoso, B., Belloch, C., Uruburu, F., & Querol, A. (1999) · International Journal of Systematic and Evolutionary Microbiology · doi:10.1099/00207713-49-1-329 · Cited by 970
Kos, B., Šušković, J., Vuković, S., Šimpraga, M., Frece, J., & Matošić, S. (2003) · Journal of Applied Microbiology · doi:10.1046/j.1365-2672.2003.01915.x · Cited by 880
Intestinal inflammation allows Salmonella to use ethanolamine to compete with the microbiota
Thiennimitr, P., Winter, S. E., Winter, M. G., Xavier, M. N., Tolstikov, V., Huseby, D. L., Sterzenbach, T., Tsolis, R. M., Roth, J. R., & Bäumler, A. J. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1107857108 · Cited by 619
Flocculation, adhesion and biofilm formation in yeasts
Verstrepen, K. J., & Klis, F. M. (2006) · Molecular Microbiology · doi:10.1111/j.1365-2958.2006.05072.x · Cited by 589
The role of microbiota in infectious disease
Stecher, B., & Hardt, W.-D. (2008) · Trends in Microbiology · doi:10.1016/j.tim.2007.12.008 · Cited by 535
Tight Junction Proteins and Signaling Pathways in Cancer and Inflammation: A Functional Crosstalk
Bhat, A. A., Uppada, S., Achkar, I. W., Hashem, S., Yadav, S. K., Shanmugakonar, M., Al-Naemi, H. A., Haris, M., & Uddin, S. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2018.01942 · Cited by 400
Discovering probiotic microorganisms: in vitro, in vivo, genetic and omics approaches
Papadimitriou, K., Zoumpopoulou, G., Foligné, B., Alexandraki, V., Kazou, M., Pot, B., & Tsakalidou, E. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.00058 · Cited by 384
Research works printed but not linked: 1
- Kurtzman, C., Fell, J.W., and Boekhout, T. (2011). The Yeasts: A Taxonomic Study, Elsevier.
Cited by
Understanding the Functionality of Probiotics on the Edge of Artificial Intelligence (AI) Era
Asar, R., Erenler, S., Devecioglu, D., Ispirli, H., Karbancioglu-Guler, F., Ozturk, H. I., & Dertli, E. (2025) · Fermentation · doi:10.3390/fermentation11050259 · Cited by 37
Metadata
- Authors
- Alvarez, S. C. V., Pendón, M. D., Bengoa, A. A., Leiva Alaniz, M. J., Maturano, Y. P., & Garrote, G. L.
- Venue
- Journal of Fungi
- Publisher
- MDPI AG
- Published
- 2024-12-17
- Volume
- 10
- Issue
- 12
- Pages
- 878
- ISSN
- 2309-608X
- Cited by
- 9
- References
- 64
- Language
- en
- Funders
- Agencia Nacional de Promoción Científica y Tecnológica (ANPCyT) (PICT 2020-03973, PICT 2019-02866, PICTA 2021-0060, FITBA A09–2022)
- Ministry of Production, Science, and Technology from Provincia de Buenos Aires (PICT 2020-03973, PICT 2019-02866, PICTA 2021-0060, FITBA A09–2022)
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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