Knowledge Graphs and Their Reciprocal Relationship with Large Language Models
Open accessAbstract
The reciprocal relationship between Large Language Models (LLMs) and Knowledge Graphs (KGs) highlights their synergistic potential in enhancing artificial intelligence (AI) applications. LLMs, with their natural language understanding and generative capabilities, support the automation of KG construction through entity recognition, relation extraction, and schema generation. Conversely, KGs serve as structured and interpretable data sources that improve the transparency, factual consistency and reliability of LLM-based applications, mitigating challenges such as hallucinations and lack of explainability. This study conducts a systematic literature review of 77 studies to examine AI methodologies supporting LLM–KG integration, including symbolic AI, machine learning, and hybrid approaches. The research explores diverse applications spanning healthcare, finance, justice, and industrial automation, revealing the transformative potential of this synergy. Through in-depth analysis, this study identifies key limitations in current approaches, including challenges in scalability with maintaining dynamic and real-time Knowledge Graphs, difficulty in adapting general-purpose LLMs to specialized domains, limited explainability in tracing model outputs to interpretable reasoning, and ethical concerns surrounding bias, fairness, and transparency. In response, the study highlights potential strategies to optimize LLM–KG synergy. The findings from this study provide actionable insights for researchers and practitioners aiming for robust, transparent, and adaptive AI systems to enhance knowledge-driven AI applications through LLM–KG integration, further advancing generative AI and explainable AI (XAI) applications.
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Structured data integration significantly enhances LLM capabilities across multiple dimensions, with knowledge graphs providing structured information that reduces hallucinations by grounding responses in verifiable facts and improving factual accuracy through clearly defined information sources.
“Structured data integration significantly enhances LLM capabilities across multiple dimensions, with knowledge graphs providing structured information that reduces hallucinations by grounding responses in verifiable facts and improving factual accuracy through clearly defined information sources [1010, 1352, 204, 571].”
From A Survey of Context Engineering for Large Language Models (2025) · cites this paper as [204]
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Systematic Mapping Studies in Software Engineering
Petersen, K., Feldt, R., Mujtaba, S., & Mattsson, M. (2008) · Electronic Workshops in Computing · doi:10.14236/ewic/ease2008.8 · Cited by 3,239 · cited 1× · see citing works
“Our study adopts a PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses—Scoping Review) [16] methodology to examine how LLMs integrate with KGs in the context of generative AI applications.”
Unifying Large Language Models and Knowledge Graphs: A Roadmap
Pan, S., Luo, L., Wang, Y., Chen, C., Wang, J., & Wu, X. (2024) · IEEE Transactions on Knowledge and Data Engineering · doi:10.1109/tkde.2024.3352100 · Cited by 1,376 · see citing works
LLMs for knowledge graph construction and reasoning: recent capabilities and future opportunities
Zhu, Y., Wang, X., Chen, J., Qiao, S., Ou, Y., Yao, Y., Deng, S., Chen, H., & Zhang, N. (2024) · World Wide Web · doi:10.1007/s11280-024-01297-w · Cited by 294 · cited 4× · see citing works
“This is crucial for applications like medical KGs, where inaccuracies can have critical implications [8].”
InfluentialExploring the Potential of Large Language Models (LLMs)in Learning on Graphs
Chen, Z., Mao, H., Li, H., Jin, W., Wen, H., Wei, X., Wang, S., Yin, D., Fan, W., Liu, H., et al. (2024) · ACM SIGKDD Explorations Newsletter · doi:10.1145/3655103.3655110 · Cited by 209 · see citing works
Graph Retrieval-Augmented Generation for Large Language Models: A Survey
Procko, T. T., & Ochoa, O. (2024) · 2024 Conference on AI, Science, Engineering, and Technology (AIxSET) · doi:10.1109/aixset62544.2024.00030 · Cited by 72 · cited 1× · see citing works
“Advanced techniques such as neural embeddings, prompt engineering, and RAG systems are employed to achieve high-precision and real-time knowledge extraction [23,42,93].”
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Cited by
Sorted by citations
A Survey of Context Engineering for Large Language Models
Mei, L., Yao, J., Ge, Y., Wang, Y., Bi, B., Cai, Y., Liu, J., Li, M., Li, Z.-Z., Zhang, D., et al. (2025) · arXiv · doi:10.48550/arxiv.2507.13334 · Cited by 13 · see citing works
- Authors
- Dehal, R. S., Sharma, M., & Rajabi, E.
- Affiliations
- Cape Breton University (CA)
- Corresponding author
- Rajabi, Enayat
- Venue
- Machine Learning and Knowledge Extraction
- Publisher
- MDPI AG
- Published
- 2025-04-21
- Volume
- 7
- Issue
- 2
- Pages
- 38
- ISSN
- 2504-4990 (ISSN-L)
- OpenAlex
- W4409634738
- Cited by
- 41
- References
- 5
- Citations by year
- 2026: 31 · 2025: 10
- FWCI
- 16.58
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Machine Learning and Knowledge Extraction (publishedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- NSERC (Natural Sciences and Engineering Research Council) Discovery Grant (RGPIN-2020-05869)
- Topics
- Physical Sciences › Computer Science › Artificial Intelligence › Topic Modeling
- Physical Sciences › Computer Science › Artificial Intelligence › Advanced Graph Neural Networks
- Physical Sciences › Computer Science › Artificial Intelligence › Semantic Web and Ontologies
- Keywords
- knowledge graphs, large language models, knowledge graph construction, entity recognition, relation extraction, schema generation, hallucination mitigation, explainable AI, interpretability, domain adaptation, bias and fairness, medical applications, financial applications, industrial automation
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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