Cited by 80Seaweed-derived Bioactive CompoundsAlgal biology and biofuel productionProbiotics and Fermented Foods

Fermentation of microalgal biomass for innovative food production

Open access
Garofalo, Cristiana, Norici, Alessandra, Mollo, Lorenzo, Osimani, Andrea, Aquilanti, Lucia·2022·Microorganisms

Abstract

Fermentation is an ancient method used worldwide to process and preserve food while enhancing its nutraceutical profile. Alga-based fermented products have recently been developed and tested due to growing interest in healthy sustainable diets, which demands the development of innovative practices in food production, operating for both human health and Earth sustainability. Algae, particularly microalgae such as Arthrospira platensis, Chlorella vulgaris, and Dunaliella salina, are already cultivated as sources of food due to their valuable compounds, including proteins, pigments, lipids, carotenoids, polyunsaturated fatty acids, steroids, and vitamins. Due to their nutritional composition, functional diversity, and flexible metabolism, microalgae represent good fermentation substrates for lactic acid bacteria (LAB) and yeasts. This review presents an overview of the scientific studies on microalga fermentation underlining microalgae’s properties and health benefits coupled with the advantages of LAB and yeast fermentation. The potential applications of and future perspectives on such functional foods are discussed.

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Crossref · 10.3390/microorganisms10102069

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  • Enzymatic hydrolysis and controlled fermentation improve digestibility, functionality, and sensory profiles of microalgae.

    “This results in improved digestibility, functionality, and sensory profiles (Parsaeimehr and Ozbay, 2024; Garofalo et al., 2022).”

    From Microalgae biotechnology and its role in sustainable and healthy food design (2025) · cites this paper as Garofalo et al., 2022

    Section 1.2 describes enzymatic breakdown during fermentation, and the Conclusions report potential gains in microalgal digestibility and bioactive properties. Section 3.4 gives examples of improved aromas, but the Conclusions also say sensory acceptability often declines, especially when products contain high percentages of microalgae. The claim overstates sensory improvement as a general result. (LLM, conf=0.86)

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  • Enzymatic hydrolysis through proteases and carbohydrases, as well as controlled fermentation with lactic acid bacteria or yeast, ruptures rigid microalgal cell walls, releases soluble peptides and nutrients, minimizes undesirable volatiles, and forms desirable aroma precursors.

    “As a result, enzymatic hydrolysis—through proteases and carbohydrases—as well as controlled fermentation processes—with lactic acid bacteria or yeast—provide the rupture of these rigid cell walls, resulting in the release of soluble peptides and nutrients, minimizing the levels of undesirable volatiles while simultaneously forming desirable aroma precursors.”

    From Microalgae biotechnology and its role in sustainable and healthy food design (2025) · cites this paper as Garofalo et al., 2022

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References 92 · Cited by 80

Research works printed but not linked: 2

  1. [25]Hu Q. Environmental Effects on Cell Composition Handbook of Microalgal Culture Richmond A. Hu Q. John Wiley & Sons, Ltd. Oxford, UK 2013 114 122 978-1-118-56716-6
  2. [37]Rani K. Sandal N. Sahoo P. A Comprehensive Review on Chlorella-Its Composition, Health Benefits, Market and Regulatory Scenario Pharma Innov. 2018 7 584 589

Authors
Garofalo, C., Norici, A., Mollo, L., Osimani, A., & Aquilanti, L.
Affiliations
Marche Polytechnic University (IT)
Corresponding author
Aquilanti, Lucia
Venue
Microorganisms
Publisher
MDPI AG
Published
2022-10-19
Volume
10
Issue
10
Pages
2069
ISSN
2076-2607 (ISSN-L)
OpenAlex
W4306835844
Cited by
80
References
92
Citations by year
2026: 22 · 2025: 25 · 2024: 22 · 2023: 10
FWCI
1.21
Type
journal article
Language
en
Open access
Locations
  • Microorganisms (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • Università Politecnica delle Marche (Università Politecnica delle Marche) (submittedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
  • Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
Keywords
microalgal biomass, Spirulina platensis, Chlorella vulgaris, Dunaliella salina, lactic acid bacteria fermentation, yeast fermentation, functional foods, nutraceuticals, carotenoids, polyunsaturated fatty acids, sustainable diets, health benefits

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