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Cited by 481

The DOI matches its Crossref record; 148 of the 148 references it cites were found in a registry or an index.

Chitosan-Based Nanomaterials for Drug Delivery

Open access
Li, Jianghua, Cai, Chao, Li, Jiarui, Li, Jun, Li, Jia, Sun, Tiantian, Wang, Lihao, Wu, Haotian, Yu, Guangli·2018·Molecules

Abstract

This review discusses different forms of nanomaterials generated from chitosan and its derivatives for controlled drug delivery. Nanomaterials are drug carriers with multiple features, including target delivery triggered by environmental, pH, thermal responses, enhanced biocompatibility, and the ability to cross the blood-brain barrier. Chitosan (CS), a natural polysaccharide largely obtained from marine crustaceans, is a promising drug delivery vector for therapeutics and diagnostics, owing to its biocompatibility, biodegradability, low toxicity, and structural variability. This review describes various approaches to obtain novel CS derivatives, including their distinct advantages, as well as different forms of nanomaterials recently developed from CS. The advanced applications of CS-based nanomaterials are presented here in terms of their specific functions. Recent studies have proven that nanotechnology combined with CS and its derivatives could potentially circumvent obstacles in the transport of drugs thereby improving the drug efficacy. CS-based nanomaterials have been shown to be highly effective in targeted drug therapy.

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Crossref · 10.3390/molecules23102661

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Metadata

Authors
Li, J., Cai, C., Li, J., Li, J., Li, J., Sun, T., Wang, L., Wu, H., & Yu, G.
Venue
Molecules
Publisher
MDPI AG
Published
2018-10-16
Volume
23
Issue
10
Pages
2661
ISSN
1420-3049 (ISSN-L)
OpenAlex
W2896623073
Cited by
481
References
148
FWCI
16.92
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Chitosan-Based Nanomaterials for Drug Delivery. https://app.cochat.ai/papers/10.3390/molecules23102661
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Li, J., Cai, C., Li, J., Li, J., Li, J., Sun, T., Wang, L., Wu, H., & Yu, G. (2018). Chitosan-Based Nanomaterials for Drug Delivery. Molecules. https://doi.org/10.3390/molecules23102661

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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