Perspectives for New and More Efficient Multifunctional Ligands for Alzheimer′s Disease Therapy

Cites (222)

Items 201–222 of 222

1. New tacrine–acridine hybrids as promising multifunctional drugs for potential treatment of Alzheimer's disease
   Nina V. Chufarova, Kamila Czarnecka, Robert Skibiński, Magda Cuchra, Ireneusz Majsterek, Paweł Szymański · 2018 · Archiv der Pharmazie
2. Mitochondria as a target for neuroprotection: implications for Alzheimer´s disease
   Susana Cardoso, Raquel Maria Fino Seiça, Paula Isabel Moreira · 2016 · Expert Review of Neurotherapeutics
3. Total Synthesis of Pulmonarin B and Design of Brominated Phenylacetic Acid/Tacrine Hybrids: Marine Pharmacophore Inspired Discovery of New ChE and Aβ Aggregation Inhibitors
   Zhiqiang Cheng, Jia-Li Song, Kongkai Zhu, Juan Zhang, Cheng‐Shi Jiang, Hua Zhang · 2018 · Marine Drugs
4. Development and Application of a Virtual Screening Protocol for the Identification of Multitarget Fragments
   Giovanni Bottegoni, Marina Veronesi, Paola Bisignano, Puneet Kacker, Angelo Danilo Favia, Andrea Cavalli · 2015 · ChemMedChem
5. Design, synthesis, cholinesterase inhibition and molecular modelling study of novel tacrine hybrids with carbohydrate derivatives
   João Paulo Bizarro Lopes, Luana Aparecida Alves da Silva, Gabriela Da Costa Franarin, Marco Antônio Ceschi, Diogo Seibert Lüdtke, Rafael Ferreira Dantas, Cristiane Martins Cardoso de Salles, Floriano Paes Silva, Mário Roberto Senger, Isabella Alvim Guedes et al. · 2018 · Bioorganic & Medicinal Chemistry
6. Design, synthesis and evaluation of novel 5, 6, 7-trimethoxyflavone–6-chlorotacrine hybrids as potential multifunctional agents for the treatment of Alzheimer's disease
   Liao, Shixian, Deng, Hui, Huang, Shengbin, Yang, Jingyuan, Wang, Siqian, Yin, Baodi, Zheng, Tieli, Zhang, Dafeng, Liu, Jinsong, Gao, Guohui et al. · 2015 · Bioorganic & Medicinal Chemistry Letters
7. The prototypical histamine H3 receptor inverse agonist thioperamide improves multiple aspects of memory processing in an inhibitory avoidance task
   Yana Charlier, Christian Brabant, Maria Elisa Serrano Navacerrada · 2013 · Behavioural Brain Research
8. Design, synthesis and evaluation of a novel metal chelator as multifunctional agents for the treatment of Alzheimer’s disease
   Yingying Wang, Yue Yang, Kwon Ho Hong, Yao Ning, Ping Yu, Jinghui Ren, Min Ji, Jin Cai · 2019 · Bioorganic Chemistry
9. Synthesis and Biological Activity of Some Benzochromenoquinolinones: Tacrine Analogs as Potent Anti‐Alzheimer's Agents
   Mohammad Reza Mahdavi, Roshanak Hariri, Seyedeh Sara Mirfazli, Hania Lotfian, Arezoo Rastergari, Omidreza Firuzi, Najmeh Edraki, Bagher A. Larijani, Tahmineh Akbarzadeh, Mina Saeedi · 2019 · Chemistry & Biodiversity
10. Cellular model of neuronal atrophy induced by DYNC1I1 deficiency reveals protective roles of RAS-RAF-MEK signaling
    Zhi-Dong Liu, Su Zhang, Hao Jianjin, Taorong Xie, Jian‐Sheng Kang · 2016 · Protein & Cell
11. Donepezil-based hybrids as multifunctional anti-Alzheimer's disease chelating agents: Effect of positional isomerization
    Marina Costa, Romane Josselin, Diana Filipa Silva, Sandra M. Cardoso, Nóra V. May, Sı́lvia Chaves, Maria Amélia Santos · 2020 · Journal of Inorganic Biochemistry
12. Facts, Results, and Perspectives of the Current Alzheimer’s Disease Research
    Jose Luis Marco-Contelles · 2019 · ACS Chemical Neuroscience
13. Tacrine-xanomeline and tacrine-iperoxo hybrid ligands: Synthesis and biological evaluation at acetylcholinesterase and M1 muscarinic acetylcholine receptors
    Marco Maspero, Daniela Volpato, Davide Cirillo, Natalia Yuan Chen, Regina Messerer, Christoph Sotriffer, Marco De Amici, Ulrike Holzgrabe, Clelia Dallanoce · 2020 · Bioorganic Chemistry
14. Designing Dual Transglutaminase 2/Histone Deacetylase Inhibitors Effective at Halting Neuronal Death
    Manuela Basso, Huan Huan Chen, Debasmita Tripathy, Mariarosaria Conte, Kim Yang-Ping Apperley, Angela De Simone, Jeffrey W. Keillor, Rajiv R. Ratan, Angela Nebbioso, Federica Sarno et al. · 2017 · ChemMedChem
15. The development of 2-acetylphenol-donepezil hybrids as multifunctional agents for the treatment of Alzheimer’s disease
    Gaofeng Zhu, Keren Wang, Jian Shi, Pengfei Zhang, Dan Yang, Xiaotian Fan, Ziyi Zhang, Wenmin Liu, Zhipei Sang · 2019 · Bioorganic & Medicinal Chemistry Letters
16. Combining Chalcones with Donepezil to Inhibit Both Cholinesterases and Aβ Fibril Assembly
    Nishad Thamban Chandrika, Marina Y. Fosso, Oleg V. Tsodikov, Harry LeVine, Sylvie Garneau‐Tsodikova · 2019 · Molecules
17. Introducing transglutaminase into the study of Alzheimer's disease. A personal look back
    Dennis J. Selkoe · 2002 · Neurochemistry International
18. Alzheimer's Disease: Microenvironment Remodeling Micelles for Alzheimer's Disease Therapy by Early Modulation of Activated Microglia (Adv. Sci. 4/2019)
    Yifei Lü, Zhongyuan Guo, Yujie Zhang et al. · 2019 · Advanced Science
19. Epigenetic processes in Alzheimer's disease
    Isabel Castanho, Katie Lunnon · 2019 · Elsevier eBooks
20. Synthesis and Biological Evaluation of Novel Chromone+Donepezil Hybrids for Alzheimer’s Disease Therapy
    R.S. Malek, Bernard Refouvelet, Mohamed Benchekroun, Isabel Iriepa, Ignacio Moraleda, Rudolf Andrýs, Kamil Musílek, Jose Luis Marco, Lhassane Ismaïli · 2019 · Current Alzheimer Research
21. Identifying Therapeutic Targets for Alzheimer’s Disease With Big Data
    Nilüfer Ertekin‐Taner · 2017 · Neurodegenerative Disease Management
22. Tacrine-Flavonoid Quercetin Hybride as a MTDL Ligand against Alzheimer’s Disease with Metal Chelating and AChE, BChE, AChE-induced Aβ Aggregation Inhibition Properties: A Computational Study
    Razieh Habibpour Gharacheh, Mahboobeh Eslami, Parisa Amani · 2019 · Physical chemistry research