The DOI matches its Crossref record; 236 of the 236 references it cites were found in a registry or an index.
Antimicrobial Properties of Chitosan and Chitosan Derivatives in the Treatment of Enteric Infections
Open accessAbstract
Antibiotics played an important role in controlling the development of enteric infection. However, the emergence of antibiotic resistance and gut dysbiosis led to a growing interest in the use of natural antimicrobial agents as alternatives for therapy and disinfection. Chitosan is a nontoxic natural antimicrobial polymer and is approved by GRAS (Generally Recognized as Safe by the United States Food and Drug Administration). Chitosan and chitosan derivatives can kill microbes by neutralizing negative charges on the microbial surface. Besides, chemical modifications give chitosan derivatives better water solubility and antimicrobial property. This review gives an overview of the preparation of chitosan, its derivatives, and the conjugates with other polymers and nanoparticles with better antimicrobial properties, explains the direct and indirect mechanisms of action of chitosan, and summarizes current treatment for enteric infections as well as the role of chitosan and chitosan derivatives in the antimicrobial agents in enteric infections. Finally, we suggested future directions for further research to improve the treatment of enteric infections and to develop more useful chitosan derivatives and conjugates.
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1 retracted
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Self-citationDiversity of the Human Intestinal Microbial Flora
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Changes of Intestinal Functions in Liver Cirrhosis
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Self-citationRevised Estimates for the Number of Human and Bacteria Cells in the Body
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“Environmental factors interact with endogenous factors to form individuals’ unique microbial phenotypes [174].”
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Cited by
Naik, G. A. R. R., Roy, A. A., Mutalik, S., & Dhas, N. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.134977 · Cited by 47
Metadata
- Authors
- Yan, D., Li, Y., Liu, Y., Li, N., Zhang, X., & Yan, C.
- Venue
- Molecules
- Publisher
- MDPI AG
- Published
- 2021-11-25
- Volume
- 26
- Issue
- 23
- Pages
- 7136
- ISSN
- 1420-3049 (ISSN-L)
- OpenAlex
- W3215655803
- Cited by
- 608
- References
- 236
- FWCI
- 14.88
- Type
- journal article
- Language
- en
- Open access
- gold
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- Yan, D., Li, Y., Liu, Y., Li, N., Zhang, X., & Yan, C. (2021). Antimicrobial Properties of Chitosan and Chitosan Derivatives in the Treatment of Enteric Infections. Molecules. https://doi.org/10.3390/molecules26237136
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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