Recent advances in supercritical CO2 extraction of pigments, lipids and bioactive compounds from microalgae
Open accessAbstract
extraction is a green method that combines economic and environmental benefits. Microalgae, on the other hand, is a biomass in abundance, capable of providing a vast variety of valuable compounds, finding applications in the food industry, cosmetics, pharmaceuticals and biofuels. An extensive study on the existing literature concerning supercritical fluid extraction (SFE) of microalgae has been carried out focusing on carotenoids, chlorophylls, lipids and fatty acids recovery, as well as the bioactivity of the extracts. Moreover, kinetic models used to describe SFE process and experimental design are included. Finally, biomass pretreatment processes applied prior to SFE are mentioned, and other extraction methods used as benchmarks are also presented.
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SFE is an environmentally friendly process that utilizes supercritical fluids as solvents to extract compounds from solid substrates.
“SFE is an environmentally friendly process that utilizes supercritical fluids as solvents to extract compounds from solid substrates [127].”
From A comprehensive review of ultrasonic assisted extraction (UAE) for bioactive components: Principles, advantages, equipment, and combined technologies (2023) · cites this paper as [127]
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References 159 · Cited by 135
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- Authors
- Tzima, S., Georgiopoulou, I., Louli, V., & Magoulas, K.
- Affiliations
- Laboratory of Thermodynamics and Transport Phenomena, School of Chemical Engineering, National Technical University of Athens (NTUA), Zografou Campus, 15780 Athens, Greece
- National Technical University of Athens (GR)
- Corresponding author
- Magoulas, Kostis
- Venue
- Molecules
- Publisher
- MDPI AG
- Published
- 2023-02-02
- Volume
- 28
- Issue
- 3
- Pages
- 1410
- ISSN
- 1420-3049 (ISSN-L)
- PMC
- PMC9920624
- OpenAlex
- W4319035502
- Cited by
- 135
- References
- 159
- Citations by year
- 2026: 48 · 2025: 45 · 2024: 29 · 2023: 13
- FWCI
- 2.07
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Molecules (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DSpace - NTUA (National Technical University of Athens) (submittedVersion, cc-by-nc-nd)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- National Technical University of Athens (NTUA)
- Topics
- Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
- Physical Sciences › Engineering › Biomedical Engineering › Phase Equilibria and Thermodynamics
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Keywords
- supercritical CO2 extraction, microalgae, carotenoids, chlorophyll, lipids, fatty acids, bioactive compounds, extraction kinetics, biomass pretreatment, green extraction
- MeSH terms
- Carbon Dioxide, Carotenoids, Fatty Acids, Biomass, Chromatography, Supercritical Fluid, Microalgae
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