Cited by 34Skin Protection and AgingPhytochemicals and Antioxidant ActivitiesMedicinal Plant Research

A Novel Approach in Skin Care: By-Product Extracts as Natural UV Filters and an Alternative to Synthetic Ones

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Ferreira, Sara M., Gomes, Sandra M., Santos, Lúcia·2023·Molecules

Abstract

The cosmetic industry has been focusing on replacing synthetic ingredients with natural ones, taking advantage of their bioactive compounds. This work assessed the biological properties of onion peel (OP) and passion fruit peel (PFP) extracts in topical formulations as an alternative to synthetic antioxidants and UV filters. The extracts were characterized regarding their antioxidant capacity, antibacterial capacity and sun protection factor (SPF) value. Results revealed that the OP extract exhibited better results, which can result from the high concentrations of quercetin, as identified and quantified in HPLC analysis. Afterward, nine formulations of O/W creams were produced with minor changes in the quantity of additives: OP and PFP extract (natural antioxidants and UV filters), BHT (synthetic antioxidant) and oxybenzone (synthetic UV filter). The stability of the formulations was determined for 28 days; it was verified that they remained stable throughout the study period. The assays of the formulations’ antioxidant capacity and SPF value revealed that OP and PFP extracts have some photoprotective properties and are excellent sources of antioxidants. As a result, they can be incorporated in daily moisturizers with SPF and sunscreens replacing and/or diminishing the quantities of synthetic ingredients, reducing their negative effects on human health and the environment.

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References 44 · Cited by 34

Authors
Ferreira, S. M., Gomes, S. M., & Santos, L.
Affiliations
Universidade do Porto (PT)
Corresponding author
Santos, Lúcia
Venue
Molecules
Publisher
MDPI AG
Published
2023-02-21
Volume
28
Issue
5
Pages
2037
ISSN
1420-3049 (ISSN-L)
OpenAlex
W4321498199
Cited by
34
References
44
Citations by year
2026: 6 · 2025: 12 · 2024: 11 · 2023: 5
FWCI
9.38
Type
journal article
Language
en
Open access
Locations
  • Molecules (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) (submittedVersion, other-oa)
Funders
  • ALiCE (LA/P/0045/2020, UIDB/00511/2020, UIDP/00511/2020)
  • LEPABE (LA/P/0045/2020, UIDB/00511/2020, UIDP/00511/2020)
  • FCT/MCTES (PIDDAC) (LA/P/0045/2020, UIDB/00511/2020, UIDP/00511/2020)
Topics
  • Health Sciences › Medicine › Dermatology › Skin Protection and Aging
  • Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
Keywords
onion peel extract, natural UV filters, benzophenone-3, butylated hydroxytoluene, quercetin, antioxidant capacity, antibacterial activity, sun protection factor, topical cream formulation, formulation stability, photoprotection, skin care
MeSH terms
Antioxidants, Humans, Plant Extracts, Skin, Sunscreening Agents, Ultraviolet Rays, Skin Care, Sun Protection Factor

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