The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Effect of Postoperative Coffee Consumption on Postoperative Ileus after Abdominal Surgery: An Updated Systematic Review and Meta-Analysis
Abstract
Background: Previous systematic reviews have not clarified the effect of postoperative coffee consumption on the incidence of postoperative ileus (POI) and the length of hospital stay (LOS). We aimed to assess its effect on these postoperative outcomes. Methods: Studies evaluating postoperative coffee consumption were searched using electronic databases until September 2021 to perform random-effect meta-analysis. The quality of evidence was assessed using the Cochrane risk-of-bias tool. Caffeinated and decaffeinated coffee were also compared. Results: Thirteen trials (1246 patients) and nine ongoing trials were included. Of the 13 trials, 6 were on colorectal surgery, 5 on caesarean section, and 2 on gynecological surgery. Coffee reduced the time to first defecation (mean difference (MD) −10.1 min; 95% confidence interval (CI) = −14.5 to −5.6), POI (risk ratio 0.42; 95% CI = 0.26 to 0.69); and LOS (MD −1.5; 95% CI = −2.7 to −0.3). This trend was similar in colorectal and gynecological surgeries. Coffee had no adverse effects. There was no difference in POI or LOS between caffeinated and decaffeinated coffee (p > 0.05). The certainty of evidence was low to moderate. Conclusion: This review showed that postoperative coffee consumption, regardless of caffeine content, likely reduces POI and LOS after colorectal and gynecological surgery.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The most recent review and meta-analysis on postoperative ileus was published at the end of 2021 [117] and included 13 trials concerning colorectal surgeries, cesarean sections, and gynecologic surgeries on a total of 1246 patients.”
From Effects of Coffee on the Gastro-Intestinal Tract: A Narrative Review and Literature Update (2022) · cites this paper as [117]
In the citing paper
“Each of them included between four and thirteen randomized control trials concerning both colorectal and gynecological interventions and compared coffee consumption either to water or to no intervention [113,114,115,116,117].”
From Effects of Coffee on the Gastro-Intestinal Tract: A Narrative Review and Literature Update (2022) · cites this paper as [117]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
RoB 2: a revised tool for assessing risk of bias in randomised trials
Sterne, J. A. C., Savović, J., Page, M. J., Elbers, R. G., Blencowe, N. S., Boutron, I., Cates, C. J., Cheng, H.-Y., Corbett, M. S., Eldridge, S. M., et al. (2019) · BMJ · doi:10.1136/bmj.l4898 · Cited by 34,787
Imputing missing standard deviations in meta-analyses can provide accurate results
Furukawa, T. A., Barbui, C., Cipriani, A., Brambilla, P., & Watanabe, N. (2006) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2005.06.006 · Cited by 1,568
Research works printed but not linked: 47
- Wolff, 2007, Patterns of gastrointestinal recovery after bowel resection and total abdominal hysterectomy: Pooled results from the placebo arms of alvimopan phase III North American clinical trials, J. Am. Coll. Surg., 205, 43, 10.1016/j.jamcollsurg.2007.02.026 · DOI
- Scarborough, 2017, Associations of specific postoperative complications with outcomes after elective colon resection: A procedure-targeted approach toward surgical quality improvement, JAMA Surg., 152, e164681, 10.1001/jamasurg.2016.4681 · DOI
- Gero, 2017, Postoperative ileus: In search of an international consensus on definition, diagnosis, and treatment, Langenbecks Arch. Surg., 402, 149, 10.1007/s00423-016-1485-1 · DOI
- Iyer, 2009, Economic burden of postoperative ileus associated with colectomy in the United States, J. Manag. Care Pharm., 15, 485
- Asgeirsson, 2010, Postoperative ileus: It costs more than you expect, J. Am. Coll. Surg., 210, 228, 10.1016/j.jamcollsurg.2009.09.028 · DOI
- Peters, 2020, The clinical and economical impact of postoperative ileus in patients undergoing colorectal surgery, Neurogastroenterol. Motil., 32, e13862, 10.1111/nmo.13862 · DOI
- Abalo, R. (2021). Coffee and caffeine consumption for human health. Nutrients, 13. · DOI
- Mattioli, 2007, Effects of caffeine and coffee consumption on cardiovascular disease and risk factors, Future Cardiol., 3, 203, 10.2217/14796678.3.2.203 · DOI
- Kiss, 2017, Involvement of adenosine A3 receptors in the chemotactic navigation of macrophages towards apoptotic cells, Immunol. Lett., 183, 62, 10.1016/j.imlet.2017.02.002 · DOI
- Gustafsson, 2019, Guidelines for perioperative care in elective colorectal surgery: Enhanced Recovery After Surgery (ERAS®) Society Recommendations: 2018, World J. Surg., 43, 659, 10.1007/s00268-018-4844-y · DOI · Paper page
- Nelson, 2019, Guidelines for perioperative care in gynecologic/oncology: Enhanced Recovery After Surgery (ERAS) Society recommendations—2019 update, Int. J. Gynecol. Cancer, 29, 651, 10.1136/ijgc-2019-000356 · DOI · Paper page
- Eamudomkarn, 2018, Effect of postoperative coffee consumption on gastrointestinal function after abdominal surgery: A systematic review and meta-analysis of randomized controlled trials, Sci. Rep., 8, 17349, 10.1038/s41598-018-35752-2 · DOI · Paper page
- Gkegkes, 2020, Effect of caffeine intake on postoperative ileus: A systematic review and meta-analysis, Dig. Surg., 37, 22, 10.1159/000496431 · DOI · Paper page
- Cornwall, 2020, Coffee to go? The effect of coffee on resolution of ileus following abdominal surgery: A systematic review and meta-analysis of randomised controlled trials, Clin. Nutr., 39, 1385, 10.1016/j.clnu.2019.06.003 · DOI · Paper page
- Kane, T.D., Tubog, T.D., and Schmidt, J.R. (2020). The use of coffee to decrease the incidence of postoperative ileus: A systematic review and meta-analysis. J. Perianesth. Nurs., 35. · DOI · Paper page
- Shamseer, 2015, Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: Elaboration and explanation, BMJ, 350, g7647, 10.1136/bmj.g7647 · DOI · Paper page
- Guyatt, 2011, GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables, J. Clin. Epidemiol., 64, 383, 10.1016/j.jclinepi.2010.04.026 · DOI · Paper page
- Rahbari, 2012, Randomized clinical trial on the effect of coffee on postoperative ileus following elective colectomy, Br. J. Surg., 99, 1530, 10.1002/bjs.8885 · DOI · Paper page
- Dulskas, 2015, Effect of coffee on the length of postoperative ileus after elective laparoscopic left-sided colectomy: A randomized, prospective single-center study, Dis. Colon Rectum., 58, 1064, 10.1097/DCR.0000000000000449 · DOI · Paper page
- Piric, 2015, The Effects of Drinking Coffee While Recovering from Colon and Rectal Resection Surgery, Med. Arch., 69, 357, 10.5455/medarh.2015.69.357-361 · DOI · Paper page
- Goymen, 2017, Effect of gum chewing and coffee consumption on intestinal motility in caesarean sections, J. Clin. Anal. Med., 8, 411e5
- Güngördük, K., Özdemir, İ.A., Güngördük, Ö., Gülseren, V., Gokçü, M., and Sancı, M. (2017). Effects of coffee consumption on gut recovery after surgery of gynecological cancer patients: A randomized controlled trial. Am. J. Obstet Gynecol., 216. · DOI · Paper page
- Mohamed, S. (2021, October 01). Immediate Postoperative Coffee Consumption Stimulates Early Gut Recovery after Cesarean Section. Available online: https://www.semanticscholar.org/paper/Immediate-Postoperative-Coffee-Consumption-Early-Sherbeny/8b790eb67f979bea8affae03fe5010167ae166c0?p2df.
- Rabiepoor, 2018, Does coffee affect the bowel function after caesarean section?, Eur. J. Obstet. Gynecol. Reprod. Biol., 220, 96, 10.1016/j.ejogrb.2017.07.028 · DOI · Paper page
- Linecker, 2019, Does coffee intake reduce postoperative ileus after laparoscopic elective colorectal surgery? A prospective, randomized controlled study: The coffee study, Dis. Colon Rectum, 62, 997, 10.1097/DCR.0000000000001405 · DOI
- Hayashi, 2019, Quantification of the effects of coffee on postoperative ileus after laparoscopic ventral rectopexy: A randomized controlled trial, Eur. Surg., 51, 325, 10.1007/s10353-019-0605-x · DOI
- Gokbel, 2020, Can coffee consumption be used to accelerate the recovery of bowel function after cesarean section? Randomized prospective trial, Ginekol. Pol., 91, 85, 10.5603/GP.2020.0014 · DOI · Paper page
- Gungorduk, 2020, Coffee consumption for recovery of intestinal function after laparoscopic gynecological surgery: A randomized controlled trial, Int. J. Surg., 82, 130, 10.1016/j.ijsu.2020.08.016 · DOI · Paper page
- 2021, Effects of acupressure, gum chewing and coffee consumption on the gastrointestinal system after caesarean section under spinal anaesthesia, J. Obstet Gynaecol., 41, 573, 10.1080/01443615.2020.1787363 · DOI
- Parnasa, 2021, Does caffeine enhance bowel recovery after elective colorectal resection? A prospective double-blinded randomized clinical trial, Tech. Coloproctol., 25, 831, 10.1007/s10151-021-02450-7 · DOI · Paper page
- Lohsiriwat, 2020, Enhanced recovery after surgery in emergency resection for obstructive colorectal cancer: A systematic review and meta-analysis, Int. J. Colorectal. Dis., 35, 1453, 10.1007/s00384-020-03652-5 · DOI
- McKechnie, 2021, Selective opioid antagonists following bowel resection for prevention of postoperative ileus: A systematic review and meta-analysis, J. Gastrointest. Surg., 25, 1601, 10.1007/s11605-021-04973-8 · DOI
- Mattioli, 2018, Coffee in hypertensive women with asymptomatic peripheral arterial disease: A potential nutraceutical effect, J. Cardiovasc. Med., 19, 183, 10.2459/JCM.0000000000000626 · DOI
- Echeverri, 2010, Caffeine’s Vascular Mechanisms of Action, Int. J. Vasc. Med., 2010, 834060
- Mattioli, 2020, Effects of caffeine on colon: A potential clinical use of coffee in surgical patients, Dig. Surg., 37, 265, 10.1159/000499198 · DOI
- Cui, 2020, Caffeine and its main targets of colorectal cancer, World J. Gastrointest. Oncol., 12, 149, 10.4251/wjgo.v12.i2.149 · DOI
- Liu, 2021, Impact of drinking Chinese green tea on postoperative short outcomes for gastric cancer: A randomized controlled trial, Eur. J. Clin. Nutr., 75, 1568, 10.1038/s41430-021-00868-8 · DOI
- Tajik, 2017, The potential effects of chlorogenic acid, the main phenolic components in coffee, on health: A comprehensive review of the literature, Eur. J. Nutr., 56, 2215, 10.1007/s00394-017-1379-1 · DOI · Paper page
- Almeida, 2006, Evaluation of the anti-inflammatory, analgesic and antipyretic activities of the natural polyphenol chlorogenic acid, Biol. Pharm. Bull., 29, 2236, 10.1248/bpb.29.2236 · DOI · Paper page
- Krakauer, 2002, The polyphenol chlorogenic acid inhibits staphylococcal exotoxin-induced inflammatory cytokines and chemokines, Immunopharmacol. Immunotoxicol., 24, 113, 10.1081/IPH-120003407 · DOI
- Li, 2019, Caffeinated and decaffeinated coffee consumption and risk of all-cause mortality: A dose-response meta-analysis of cohort studies, J. Hum. Nutr. Diet., 32, 279, 10.1111/jhn.12633 · DOI
- Kennedy, 2017, Coffee, including caffeinated and decaffeinated coffee, and the risk of hepatocellular carcinoma: A systematic review and dose-response meta-analysis, BMJ Open, 7, e013739, 10.1136/bmjopen-2016-013739 · DOI · Paper page
- Casiglia, 1991, Haemodynamic effects of coffee and caffeine in normal volunteers: A placebo-controlled clinical study, J. Intern. Med., 229, 501, 10.1111/j.1365-2796.1991.tb00385.x · DOI
- Ribeiro, 2020, Safety of coffee consumption after myocardial infarction: A systematic review and meta-analysis, Nutr. Metab. Cardiovasc. Dis., 30, 2146, 10.1016/j.numecd.2020.07.016 · DOI
- Kelly, 2013, Outpatient versus inpatient induction of labour for improving birth outcomes, Cochrane Database Syst. Rev., 11, CD007372
- Riera, 2016, Chewing gum for enhancing early recovery of bowel function after caesarean section, Cochrane Database Syst. Rev., 10, CD011562
- Hamel, 2021, Comparison of treatment to improve gastrointestinal functions after colorectal surgery within enhanced recovery programmes: A systematic review and meta-analysis, Sci. Rep., 11, 7423, 10.1038/s41598-021-86699-w · DOI
Cited by
Effects of Coffee on the Gastro-Intestinal Tract: A Narrative Review and Literature Update
Nehlig, A. (2022) · Nutrients · doi:10.3390/nu14020399 · Cited by 158
Metadata
- Authors
- Watanabe, J., Miki, A., Koizumi, M., Kotani, K., & Sata, N.
- Venue
- Nutrients
- Publisher
- MDPI AG
- Published
- 2021-12-08
- Volume
- 13
- Issue
- 12
- Pages
- 4394
- ISSN
- 2072-6643
- Cited by
- 34
- References
- 2
- Language
- en
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Effect of Postoperative Coffee Consumption on Postoperative Ileus after Abdominal Surgery: An Updated Systematic Review and Meta-Analysis. https://app.cochat.ai/papers/10.3390/nu13124394
- The paper
- Watanabe, J., Miki, A., Koizumi, M., Kotani, K., & Sata, N. (2021). Effect of Postoperative Coffee Consumption on Postoperative Ileus after Abdominal Surgery: An Updated Systematic Review and Meta-Analysis. Nutrients. https://doi.org/10.3390/nu13124394
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.