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Effect of Postoperative Coffee Consumption on Postoperative Ileus after Abdominal Surgery: An Updated Systematic Review and Meta-Analysis

Watanabe, Jun, Miki, Atsushi, Koizumi, Masaru, Kotani, Kazuhiko, Sata, Naohiro·2021·Nutrients

Abstract

Background: Previous systematic reviews have not clarified the effect of postoperative coffee consumption on the incidence of postoperative ileus (POI) and the length of hospital stay (LOS). We aimed to assess its effect on these postoperative outcomes. Methods: Studies evaluating postoperative coffee consumption were searched using electronic databases until September 2021 to perform random-effect meta-analysis. The quality of evidence was assessed using the Cochrane risk-of-bias tool. Caffeinated and decaffeinated coffee were also compared. Results: Thirteen trials (1246 patients) and nine ongoing trials were included. Of the 13 trials, 6 were on colorectal surgery, 5 on caesarean section, and 2 on gynecological surgery. Coffee reduced the time to first defecation (mean difference (MD) −10.1 min; 95% confidence interval (CI) = −14.5 to −5.6), POI (risk ratio 0.42; 95% CI = 0.26 to 0.69); and LOS (MD −1.5; 95% CI = −2.7 to −0.3). This trend was similar in colorectal and gynecological surgeries. Coffee had no adverse effects. There was no difference in POI or LOS between caffeinated and decaffeinated coffee (p > 0.05). The certainty of evidence was low to moderate. Conclusion: This review showed that postoperative coffee consumption, regardless of caffeine content, likely reduces POI and LOS after colorectal and gynecological surgery.

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Research works printed but not linked: 47

  1. Wolff, 2007, Patterns of gastrointestinal recovery after bowel resection and total abdominal hysterectomy: Pooled results from the placebo arms of alvimopan phase III North American clinical trials, J. Am. Coll. Surg., 205, 43, 10.1016/j.jamcollsurg.2007.02.026 · DOI
  2. Scarborough, 2017, Associations of specific postoperative complications with outcomes after elective colon resection: A procedure-targeted approach toward surgical quality improvement, JAMA Surg., 152, e164681, 10.1001/jamasurg.2016.4681 · DOI
  3. Gero, 2017, Postoperative ileus: In search of an international consensus on definition, diagnosis, and treatment, Langenbecks Arch. Surg., 402, 149, 10.1007/s00423-016-1485-1 · DOI
  4. Iyer, 2009, Economic burden of postoperative ileus associated with colectomy in the United States, J. Manag. Care Pharm., 15, 485
  5. Asgeirsson, 2010, Postoperative ileus: It costs more than you expect, J. Am. Coll. Surg., 210, 228, 10.1016/j.jamcollsurg.2009.09.028 · DOI
  6. Peters, 2020, The clinical and economical impact of postoperative ileus in patients undergoing colorectal surgery, Neurogastroenterol. Motil., 32, e13862, 10.1111/nmo.13862 · DOI
  7. Abalo, R. (2021). Coffee and caffeine consumption for human health. Nutrients, 13. · DOI
  8. Mattioli, 2007, Effects of caffeine and coffee consumption on cardiovascular disease and risk factors, Future Cardiol., 3, 203, 10.2217/14796678.3.2.203 · DOI
  9. Kiss, 2017, Involvement of adenosine A3 receptors in the chemotactic navigation of macrophages towards apoptotic cells, Immunol. Lett., 183, 62, 10.1016/j.imlet.2017.02.002 · DOI
  10. Gustafsson, 2019, Guidelines for perioperative care in elective colorectal surgery: Enhanced Recovery After Surgery (ERAS®) Society Recommendations: 2018, World J. Surg., 43, 659, 10.1007/s00268-018-4844-y · DOI · Paper page
  11. Nelson, 2019, Guidelines for perioperative care in gynecologic/oncology: Enhanced Recovery After Surgery (ERAS) Society recommendations—2019 update, Int. J. Gynecol. Cancer, 29, 651, 10.1136/ijgc-2019-000356 · DOI · Paper page
  12. Eamudomkarn, 2018, Effect of postoperative coffee consumption on gastrointestinal function after abdominal surgery: A systematic review and meta-analysis of randomized controlled trials, Sci. Rep., 8, 17349, 10.1038/s41598-018-35752-2 · DOI · Paper page
  13. Gkegkes, 2020, Effect of caffeine intake on postoperative ileus: A systematic review and meta-analysis, Dig. Surg., 37, 22, 10.1159/000496431 · DOI · Paper page
  14. Cornwall, 2020, Coffee to go? The effect of coffee on resolution of ileus following abdominal surgery: A systematic review and meta-analysis of randomised controlled trials, Clin. Nutr., 39, 1385, 10.1016/j.clnu.2019.06.003 · DOI · Paper page
  15. Kane, T.D., Tubog, T.D., and Schmidt, J.R. (2020). The use of coffee to decrease the incidence of postoperative ileus: A systematic review and meta-analysis. J. Perianesth. Nurs., 35. · DOI · Paper page
  16. Shamseer, 2015, Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: Elaboration and explanation, BMJ, 350, g7647, 10.1136/bmj.g7647 · DOI · Paper page
  17. Guyatt, 2011, GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables, J. Clin. Epidemiol., 64, 383, 10.1016/j.jclinepi.2010.04.026 · DOI · Paper page
  18. Rahbari, 2012, Randomized clinical trial on the effect of coffee on postoperative ileus following elective colectomy, Br. J. Surg., 99, 1530, 10.1002/bjs.8885 · DOI · Paper page
  19. Dulskas, 2015, Effect of coffee on the length of postoperative ileus after elective laparoscopic left-sided colectomy: A randomized, prospective single-center study, Dis. Colon Rectum., 58, 1064, 10.1097/DCR.0000000000000449 · DOI · Paper page
  20. Piric, 2015, The Effects of Drinking Coffee While Recovering from Colon and Rectal Resection Surgery, Med. Arch., 69, 357, 10.5455/medarh.2015.69.357-361 · DOI · Paper page
  21. Goymen, 2017, Effect of gum chewing and coffee consumption on intestinal motility in caesarean sections, J. Clin. Anal. Med., 8, 411e5
  22. Güngördük, K., Özdemir, İ.A., Güngördük, Ö., Gülseren, V., Gokçü, M., and Sancı, M. (2017). Effects of coffee consumption on gut recovery after surgery of gynecological cancer patients: A randomized controlled trial. Am. J. Obstet Gynecol., 216. · DOI · Paper page
  23. Mohamed, S. (2021, October 01). Immediate Postoperative Coffee Consumption Stimulates Early Gut Recovery after Cesarean Section. Available online: https://www.semanticscholar.org/paper/Immediate-Postoperative-Coffee-Consumption-Early-Sherbeny/8b790eb67f979bea8affae03fe5010167ae166c0?p2df.
  24. Rabiepoor, 2018, Does coffee affect the bowel function after caesarean section?, Eur. J. Obstet. Gynecol. Reprod. Biol., 220, 96, 10.1016/j.ejogrb.2017.07.028 · DOI · Paper page
  25. Linecker, 2019, Does coffee intake reduce postoperative ileus after laparoscopic elective colorectal surgery? A prospective, randomized controlled study: The coffee study, Dis. Colon Rectum, 62, 997, 10.1097/DCR.0000000000001405 · DOI
  26. Hayashi, 2019, Quantification of the effects of coffee on postoperative ileus after laparoscopic ventral rectopexy: A randomized controlled trial, Eur. Surg., 51, 325, 10.1007/s10353-019-0605-x · DOI
  27. Gokbel, 2020, Can coffee consumption be used to accelerate the recovery of bowel function after cesarean section? Randomized prospective trial, Ginekol. Pol., 91, 85, 10.5603/GP.2020.0014 · DOI · Paper page
  28. Gungorduk, 2020, Coffee consumption for recovery of intestinal function after laparoscopic gynecological surgery: A randomized controlled trial, Int. J. Surg., 82, 130, 10.1016/j.ijsu.2020.08.016 · DOI · Paper page
  29. 2021, Effects of acupressure, gum chewing and coffee consumption on the gastrointestinal system after caesarean section under spinal anaesthesia, J. Obstet Gynaecol., 41, 573, 10.1080/01443615.2020.1787363 · DOI
  30. Parnasa, 2021, Does caffeine enhance bowel recovery after elective colorectal resection? A prospective double-blinded randomized clinical trial, Tech. Coloproctol., 25, 831, 10.1007/s10151-021-02450-7 · DOI · Paper page
  31. Lohsiriwat, 2020, Enhanced recovery after surgery in emergency resection for obstructive colorectal cancer: A systematic review and meta-analysis, Int. J. Colorectal. Dis., 35, 1453, 10.1007/s00384-020-03652-5 · DOI
  32. McKechnie, 2021, Selective opioid antagonists following bowel resection for prevention of postoperative ileus: A systematic review and meta-analysis, J. Gastrointest. Surg., 25, 1601, 10.1007/s11605-021-04973-8 · DOI
  33. Mattioli, 2018, Coffee in hypertensive women with asymptomatic peripheral arterial disease: A potential nutraceutical effect, J. Cardiovasc. Med., 19, 183, 10.2459/JCM.0000000000000626 · DOI
  34. Echeverri, 2010, Caffeine’s Vascular Mechanisms of Action, Int. J. Vasc. Med., 2010, 834060
  35. Mattioli, 2020, Effects of caffeine on colon: A potential clinical use of coffee in surgical patients, Dig. Surg., 37, 265, 10.1159/000499198 · DOI
  36. Cui, 2020, Caffeine and its main targets of colorectal cancer, World J. Gastrointest. Oncol., 12, 149, 10.4251/wjgo.v12.i2.149 · DOI
  37. Liu, 2021, Impact of drinking Chinese green tea on postoperative short outcomes for gastric cancer: A randomized controlled trial, Eur. J. Clin. Nutr., 75, 1568, 10.1038/s41430-021-00868-8 · DOI
  38. Tajik, 2017, The potential effects of chlorogenic acid, the main phenolic components in coffee, on health: A comprehensive review of the literature, Eur. J. Nutr., 56, 2215, 10.1007/s00394-017-1379-1 · DOI · Paper page
  39. Almeida, 2006, Evaluation of the anti-inflammatory, analgesic and antipyretic activities of the natural polyphenol chlorogenic acid, Biol. Pharm. Bull., 29, 2236, 10.1248/bpb.29.2236 · DOI · Paper page
  40. Krakauer, 2002, The polyphenol chlorogenic acid inhibits staphylococcal exotoxin-induced inflammatory cytokines and chemokines, Immunopharmacol. Immunotoxicol., 24, 113, 10.1081/IPH-120003407 · DOI
  41. Li, 2019, Caffeinated and decaffeinated coffee consumption and risk of all-cause mortality: A dose-response meta-analysis of cohort studies, J. Hum. Nutr. Diet., 32, 279, 10.1111/jhn.12633 · DOI
  42. Kennedy, 2017, Coffee, including caffeinated and decaffeinated coffee, and the risk of hepatocellular carcinoma: A systematic review and dose-response meta-analysis, BMJ Open, 7, e013739, 10.1136/bmjopen-2016-013739 · DOI · Paper page
  43. Casiglia, 1991, Haemodynamic effects of coffee and caffeine in normal volunteers: A placebo-controlled clinical study, J. Intern. Med., 229, 501, 10.1111/j.1365-2796.1991.tb00385.x · DOI
  44. Ribeiro, 2020, Safety of coffee consumption after myocardial infarction: A systematic review and meta-analysis, Nutr. Metab. Cardiovasc. Dis., 30, 2146, 10.1016/j.numecd.2020.07.016 · DOI
  45. Kelly, 2013, Outpatient versus inpatient induction of labour for improving birth outcomes, Cochrane Database Syst. Rev., 11, CD007372
  46. Riera, 2016, Chewing gum for enhancing early recovery of bowel function after caesarean section, Cochrane Database Syst. Rev., 10, CD011562
  47. Hamel, 2021, Comparison of treatment to improve gastrointestinal functions after colorectal surgery within enhanced recovery programmes: A systematic review and meta-analysis, Sci. Rep., 11, 7423, 10.1038/s41598-021-86699-w · DOI

Metadata

Authors
Watanabe, J., Miki, A., Koizumi, M., Kotani, K., & Sata, N.
Venue
Nutrients
Publisher
MDPI AG
Published
2021-12-08
Volume
13
Issue
12
Pages
4394
ISSN
2072-6643
Cited by
34
References
2
Language
en

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Watanabe, J., Miki, A., Koizumi, M., Kotani, K., & Sata, N. (2021). Effect of Postoperative Coffee Consumption on Postoperative Ileus after Abdominal Surgery: An Updated Systematic Review and Meta-Analysis. Nutrients. https://doi.org/10.3390/nu13124394

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