Targeted alpha therapy: progress in radionuclide production, radiochemistry, and applications.
Cited by (193)
Items 101–193 of 193
- Enhancing the Therapeutic Effect of 2-211At-astato-α-methyl-L-phenylalanine with Probenecid LoadingHirofumi Hanaoka, Yasuhiro Ohshima, Hiroyuki Y. Suzuki, Ichiro Sasaki, Tadashi Watabe, Kazuhiro Ooe, Shigeki Watanabe, Noriko S. Ishioka · 2021 · Cancers
- Radiological and Molecular Analysis of Radioiodinated Anastrozole and Epirubicin as Innovative Radiopharmaceuticals Targeting Methylenetetrahydrofolate Dehydrogenase 2 in Solid TumorsMazen Abdulrahman Binmujlli · 2024 · Pharmaceutics
- Development of a 213Bi-Labeled Pyridyl Benzofuran for Targeted α-Therapy of Amyloid-β AggregatesAidan A Bender, Emily K Kirkeby, D. Cross, Satoshi Minoshima, Andrew G Roberts, Tara Mastren · 2024 · Journal of Nuclear Medicine
- A Novel Single-Step-Labeled 212Pb-CaCO3 Microparticle for Internal Alpha Therapy: Preparation, Stability, and Preclinical Data from MiceRuth Gong Li, Kim Lindland, Tina Bjørnlund Bønsdorff, Sara Westrøm, Roy H. Larsen · 2021 · Materials
- Feasibility of producing 225Ac via thermal neutron irradiation of 226Ra: A systematic theoretical studyLong Qiu, Jinsong Zhang, Tu Lan, Jiali Liao, Yuanyou Yang, Feize Li, Ning Liu · 2024 · Nuclear Analysis
- Peptide receptor radionuclide therapy: a new era of radiation nephropathyAbhirami Das, Ayse Tuba Kendi, Sandhya Manohar · 2025 · Nephrology Dialysis Transplantation
- Radiopharmaceutical: An Update and Comparison of Preclinical Investigation Result of Alpha and Beta Emitter RadioisotopeAditya Luhung, Aliya Nur Hasanah, Danni Ramdhani · 2026 · Drug Design Development and Therapy
- In vivo-stable bis-iminobiotin for targeted radionuclide delivery with the mutant streptavidinToshifumi Tatsumi, Songji Zhao, Akitomo Kasahara, Miho Aoki, Ken‐ichi Nishijima, Naoyuki Ukon, Tatsuhiko Kodama, Kazuhiro Takahashi, Akira Sugiyama, Kohshin Washiyama et al. · 2024 · Bioorganic & Medicinal Chemistry Letters
- Production of radionuclides: Cyclotrons and reactorsMartina Benešová, Gerald Reischl · 2021 · Elsevier eBooks
- Monte Carlo simulation study to explore optimum conditions for Astatine-211 SPECTAkihiko Takahashi, Ryosuke Kajiya, Shingo Baba, Masayuki Sasaki · 2023 · Radiological Physics and Technology
- The effects of nuclear level density model and alpha optical model potential to the excitation functions of novel therapeutic radionuclidesN. Kamal, Sana N. Nizam, A. Abdul Aziz · 2023 · Applied Radiation and Isotopes
- In vitro and in vivo study of 221Fr and 213Bi progeny release from the 225Ac-labelled TiO2 nanoparticlesMichal Sakmár, Ján Kozempel, Jan Kučka, Tereza Janská, Matěj Štíbr, Lukáš Ondrák, Kateřina Ondrák Fialová, Martin Vlk, Luděk Šefc, Frank Bruchertseifer et al. · 2024 · Nuclear Medicine and Biology
- Gravimetric Drop-on-Demand Inkjet Deposition for Imaging Phantoms with Traceable ActivitySean Jollota, Denis E. Bergeron, R. Michael Verkouteren, Svetlana Nour, Ryan Fitzgerald, Ohyun Kwon, Jeffrey L. Radtke, Bryan P. Bednarz, Brian W. Miller, Larry A. DeWerd · 2024 · Applied Radiation and Isotopes
- Breaking the Silence of Tumor Response: Future Prospects of Targeted Radionuclide TherapyChandan Kumar, Aanchal Udaynath Pareri, Arunkumar Singh Koijam · 2021 · Anti-Cancer Agents in Medicinal Chemistry
- Exploiting Radiation Induction of Antigens in Cancer: Targeted Drug DeliveryVaishali Kapoor, Abhay Kumar Singh, Calvin D. Lewis, Sapna Deore, Dennis E. Hallahan · 2022 · International Journal of Molecular Sciences
- Pr(H3BNMe2BH3)3 and Pr(thd)3 as Volatile Carriers for Actinium-225. Deposition of Actinium-Doped Praseodymium Boride Thin Films for Potential Use in BrachytherapyScott R. Daly, Brian J. Bellott, Daniel R. McAlister, E. Philip Horwitz, Gregory S. Girolami · 2022 · Inorganic Chemistry
- An optimization study for targeted alpha therapy: Ion behaviours and dose calculations within ICRU-compact bone tissueAyhan Kara · 2022 · Applied Radiation and Isotopes
- Production and radiochemistry of the in vivo PET generator 140Nd/140Pr as an imaging surrogate for F-block therapeutic radionuclidesMangi lal Godara, Shelbie Jaylene Cingoranelli, Volkan Tekin, Shefali Saini, Sharon L. Samuel, Hailey A. Houson, Suzanne E. Lapi · 2025 · Scientific Reports
- Emerging role of radiopharmaceutical therapy in oncology: advances, challenges, and future directionsLaura Ordas, Sean Foster, Phuc Pham, Andy S. Ollendorff, Varun Gnanasekar, Mahmoud Toulany, Quaovi H. Sodji · 2026 · JNCI Cancer Spectrum
- Design and development of the DE-SPECT system: a clinical SPECT system for broadband multi-isotope imaging of peripheral vascular diseaseElena Maria Zannoni, P Sankar, Yihong Jin, Cheng Liu, Albert J. Sinusas, Scott D. Metzler, Ling-Jian Meng · 2024 · Physics in Medicine and Biology
- Environmental geochemistry of radionuclides (Environmental radiochemistry)Yoshio Takahashi, A. Yamaguchi, Takumi Yomogida · 2024 · Treatise on Geochemistry
- Nanoradiopharmaceuticals: An Attractive Concept in OncotherapyRuitong Hou, Ning Liu, Feize Li · 2024 · ChemMedChem
- Recent advances in spatio-temporally controllable systems for management of gliomaHuiwen Zhang, Wanqi Zhu, Wei Pan, Xiuyan Wan, Na Li, Bo Tang · 2024 · Asian Journal of Pharmaceutical Sciences
- Triacetate of Benzoazacrown Compound as a Chelator for Lead Cations Promising for Targeted RadiopharmaceuticalsBayirta Vladimirovna Egorova, Lyubov Sergeevna Zamurueva, Anastasia D. Zubenko, Пашанова Анна Вячеславовна, Zeena Subramonia Pillai, Olga Anatol'evna Fedorova, Stepan Nikolaevich Kalmykov · 2021 · Macroheterocycles
- Exploring a Nuclear-Selective Radioisotope Delivery System for Efficient Targeted Alpha TherapyYuki Iizuka, Yoshiyuki Manabe, Kazuhiro Ooe, Atsushi Toyoshima, Xiaojie Yin, Hiromitsu Haba, Kazuya Kabayama, Koichi Fukase · 2023 · International Journal of Molecular Sciences
- α Emitter-Labeled Radiopeptides for Targeted α Therapy of TumorsPatrick Arthur Cieslik, Björn Wängler, Carmen Wängler · 2025 · Journal of Medicinal Chemistry
- Radiopharmaceutical therapy: From bench to bedsideQing Liang, Xiaoyan Li, Hancheng Cai, Wenyu Song, Xiaoli Lan, Michael C. Veronesi, Weibo Cai · 2025 · Acta Pharmaceutica Sinica B
- Combination therapy of an 211At-labeled RGD peptide and immune checkpoint blockade to enhance antitumor efficacyHiroaki Echigo, Masayuki Munekane, Takeshi Fuchigami, Kohshin Washiyama, Takashi Nakamura, Atsushi Furukawa, Zhuoqing Chen, Kenji Mishiro, Hiroshi Wakabayashi, Kazuhiro Takahashi et al. · 2025 · European Journal of Nuclear Medicine and Molecular Imaging
- The use of radiopharmaceuticals in targeted cancer therapy: a narrative reviewAmirreza Khalaji · 2025 · International Journal of Physiology Pathophysiology and Pharmacology
- Radiopharmaceuticals for TherapyShankar Vallabhajosula · 2023 · Springer eBooks
- Chelator Design and Radiolabeling Chemistry of RadiometalsViktoria E. Krol, Mukesh K. Pandey · 2025 · Royal Society of Chemistry eBooks
- Displacement complexing chromatography with DTPA-based eluents under irradiation conditionsOleg V. Kharitonov, L. A. Firsova, Evgeny Anatolievich Kozlitin · 2025 · Journal of Radioanalytical and Nuclear Chemistry
- Development of 223Ra-labeled polymeric nanocarriers with variable administration routes for alpha-therapy of colorectal cancerAlisa S. Postovalova, Vladislava A. Rusakova, Darya R. Akhmetova, Yulia A. Tishchenko, Dmitry S. Sysoev, Michail A. Nadporojskii, Konstantin S. Sivak, Sergei Alexandrovich Shipilovskikh, Alexander S. Timin · 2025 · Drug Delivery and Translational Research
- Ab initio multiconfigurational calculations of experimentally significant energy levels and transition rates in Lr i ( Z = 103 )Joseph S. Andrews, A. I. Bondarev, Per Jönsson, Jon Grumer, S. Raeder, S. Fritzsche, Jacek Bieroń · 2025 · Physical Review A
- Alpha Therapy Beyond TOC and TATE—Production, Quality Control, and In-Human Results for the SSTR2 Antagonist DOTA-LM3Lukas Greifenstein, Marcel Martin, Sarah Stephan, Aleksandr Eismant, Carsten Sven Kramer, Christian Landvogt, Corinna Mueller, Frank Rösch, Richard Paul Baum · 2026 · Pharmaceuticals
- Delta-like Ligand 3Directed 225 Ac Radioimmunotherapy in Neuroendocrine Lung and Prostate Cancer ModelsTran Hoang, David Bauer, Aidan Ingham, Ileana C. Miranda, Lukas M. Carter, Alexa L. Michel, Roberto De Gregorio, Juliana Welk, Hong Zhong, John Thomas Poirier et al. · 2026 · Journal of Nuclear Medicine
- Medicinal (Radio) Chemistry: Building Radiopharmaceuticals for the FutureMartha Sahylí Ortega Pijeira, Paulo Sérgio Gonçalves Nunes, Samila Leon Chaviano, Aida Mary Abreu Diaz, Jean N. DaSilva, Eduardo Ricci‐Júnior, Luciana Magalhães Rebêlo Alencar, Xiaoyuan Shawn Chen, Ralph Santos‐Oliveira · 2023 · Current Medicinal Chemistry
- Targeted Alpha Therapy in Cancer Management: Therapeutic Prospects of Nuclear Medicine in OncologySipho Mdanda, Amanda Henrietta Mdlophane, Honest Ndlovu, Keamogetswe Ramonaheng, Milani Qebetu, Johncy Mahapane, Mankgopo Kgatle, Yonwaba V. Mzizi, Reabetswe Sebatana, Zamani E. D. Cele et al. · 2023 · Interdisciplinary cancer research
- Semi-Permanent Mass Production of Ac-225 for Cancer Therapy by the (3n,x) Reaction in Pressurized Water ReactorDaiki Iwahashi, Yuto Sasaki, Tomoatsu Shinohara, Naoyuki Takaki · 2023 · Processes
- Qualitative and quantitative imaging of alpha‐emitting radiopharmaceuticalsLan Wang, Jingjing Lou, Xuecen Cao, Lina Jia, Shuai Xue, Xingdang Liu, Lan Zhang, Xiao Li · 2024 · iRadiology
- Simulation of cell cycle effects on DNA strand break induction due to α -particlesLaura Ballisat, Chiara De Sio, L. Beck, Anna L. Chambers, Mark Simon Dillingham, Susanna Guatelli, D. Sakata, Yuyao Shi, Jinyan Duan, Jaap J. Velthuis et al. · 2024 · Physica Medica
- State of the art and future perspectives of new radionuclides in Nuclear Medicine. Part IIL. Sancho, A. Roteta, I. Torres, M. de Arcocha, Rocío Ramos-Membrive, M.L. Domínguez, Juan José Rosales, Elena Prieto, Gemma Quincoces · 2025 · Revista Española de Medicina Nuclear e Imagen Molecular (English Edition)
- Preirradiation of Spheroids with 225Ac-Trastuzumab Improves Penetration of 225Ac-Liposomes and MIRDcell Predictions of Responses to Drug CocktailsHima Tallam, Rajiv Nair, Aira Sarkar, Sumudu Katugampola, Stavroula Sofou, Roger W. Howell · 2025 · Journal of Nuclear Medicine
- Delivery of radiopharmaceuticals and theranostic agents: targeted alpha therapySayandev Chatterjee, Kenneth R. Czerwinski, Hilary A. Fitzgerald, Andrew L. Lakes, Zuolei Liao, Russell C. Ludwig, Katie M. McBride, Vladislav P. Vlasenko · 2022 · Elsevier eBooks
- PSMA-Targeted Radiopharmaceuticals for Imaging and Therapy of Prostate CancerВ. К. Тищенко, Василий Михайлович Петриев, Оксана Петровна Власова, В. В. Крылов, П. В. Шегай, С. А. Иванов, А. Д. Каприн · 2022 · Physics of Atomic Nuclei
- Status of α-emitter Radioimmunoconjugates for Targeted TherapyMobina Rabiei, Ahmad Reza Vaez Alaei, Hassan Yousefnia · 2023 · Current Radiopharmaceuticals
- Crown ether-based cloud point extraction for lead-212 enrichment from thorium seriesShiquan Cao, Baijia Hao, Zhi Chen · 2024 · New Journal of Chemistry
- Voxel based 211At dosimetry using CT and SPECT data with equivalent source term optimizationJinyang Li, Xingchen Zhou, Hui Wang, Jun-Liang Du, Wenming Zhou · 2025 · Journal of Radioanalytical and Nuclear Chemistry
- Using radioactive waste for targeted alpha therapy: Advancing a sovereign Australian supply of 225Ac and 212PbGrant Douglas, Darren J. Koppel, Tom Cresswell, Simon G. Puttick, John Phalen · 2025 · Journal of Environmental Radioactivity
- Separation of radium from natural thorium by precipitation and barium carbonate co-precipitationLingyuan Liao, Rulong Ren, Jing Tang, Xuexiang He, Shunyan Ning, Yuezhou Wei, Lifeng Chen · 2025 · Journal of Radioanalytical and Nuclear Chemistry
- Dosimetry and preclinical evaluation of long-term radiotoxicity following treatment with 212Pb alpha-radioimmunotherapy targeting CD20Isabelle Quelven, Amal Saidi, Magali Sage, Erick Mora‐Ramirez, Julien J.-C. Torgue, Michel Cogné, Stéphanie Durand-Panteix · 2025 · EJNMMI Research
- Current Status of PSMA-Targeted Agents Based on Small Molecules for Prostate Cancer in Preclinical StudiesAyman Muzammal, Kyo Chul Lee, Sairan Eom · 2026 · Nuclear Medicine and Molecular Imaging
- 177Lu-PSMA for prostate cancer: progress, challenges and future perspectivesZhen Xi, Shiyu Ji, Yu Zhang, Ming-Hui Sun, Gaozhen Jia, Qi Jiang · 2026 · Asian Journal of Andrology
- The Present and Future of THERANOSTICSWinnie Wing-Chuen Lam, Sue Ping Thang, Kelvin Siu Hoong Loke, Pei Ing Ngam, Andrew Eik‐Hock Tan, Lenith Tai‐Jit Cheng, Sidney Yu, Anna Siah Lee Ler, Damian Li‐Kin Khor, Soma Somanesan et al. · 2026 · Asia-Pacific Journal of Clinical Oncology
- Radionuclide‑drug conjugates in lung cancer: advances in precision therapy and clinical translationJunzhi Liu, Xiaoyu Zuo, Xue Yang, Xinyue Wang, Lu Gan, Jianxin Xue · 2026 · Molecular Cancer
- Improved 140Nd Production for the 140Nd/140Pr In Vivo Generator through Target Recycling and Radiochemical OptimizationMangi lal Godara, Gabriel Dufour, Anna Buryachenko, Suzanne E. Lapi · 2026 · ACS Omega
- Biodistribution of 213Bi–Metallothionein and 213Bi–IgG in Intact MiceВасилий Михайлович Петриев, В. К. Тищенко, П. В. Шегай, С. А. Иванов, А. Д. Каприн · 2022 · Physics of Atomic Nuclei
- Nanoparticle-Mediated Radiation TherapyMudasir Ashraf Shah, Arfat Firdous, Ghulam Nabi Dar · 2024 · Springer eBooks
- Radiobiology of Targeted Alpha TherapyMichael K. Schultz, Jean‐Pierre Pouget, Frank R. Wuest, Bryce J. B. Nelson, Jan D. Andersson, Sarah M. Cheal, Mengshi Li, Fiorenza Ianzini, Sangeeta Ray, Stephen A. Graves et al. · 2022 · Elsevier eBooks
- Monte Carlo approach to comparison of parallel-hole collimators of clinical scintillation camera system for imaging astatine-211 (At-211)Kohei Nakanishi, Seiichi Yamamoto, J. Kataoka · 2022 · Journal of Instrumentation
- Chemistry of Therapeutic RadionuclidesShankar Vallabhajosula · 2023 · Springer eBooks
- Crown Ether-Based Cloud Point Extraction for Lead-212 Enrichment from Thorium SeriesShiquan Cao, Baijia Hao, Zhi Chen · 2024 · SSRN Electronic Journal
- Estado del arte y perspectivas futuras de nuevos radionúclidos en Medicina Nuclear: Parte IIL. Sancho, A. Roteta, I. Torres, M. de Arcocha, Rocío Ramos-Membrive, M.L. Domínguez, Juan José Rosales, Elena Prieto, Gemma Quincoces · 2025 · Revista Española de Medicina Nuclear e Imagen Molecular
- Chemical coupling of biological magnetosomes with amine‐functionalized therapeutic antibody conjugatesSandy M. Payan, Lucía Gandarias, Romain Avellan, Damien Faivre, Sandra Prévéral · 2025 · Journal of Chemical Technology & Biotechnology
- MIR dosimetry using CR-39 based α spectroscopyM Sreena, E S Keerthi, Cherumukku Vallabhan Midhun, P V Arun, M. M. Musthafa · 2025 · Applied Radiation and Isotopes
- Physical behaviors and dose calculations of alpha-emitter radionuclides ( 227 Th, 213 Bi, and 211 At) and their daughter nuclei in targeted alpha therapy for breast tissueAbayomi M. Olaosun, Caleb Ayoade Aborisade, Denen E. Shian, Peter Taiwo Osuolale, Oluwaseun Olaitan Oloyede, Fatai Akintunde Balogun · 2025 · Radiation effects and defects in solids
- Roadmap of development of trackable anticancer agents based on metal complexes “Strategies and Perspectives for Precision Oncology and theranostics”Ewen Bodio, Julie Pineau · 2025 · Advances in inorganic chemistry
- Additional file 1 of In vivo stable 211At-labeled prostate-specific membrane antigen-targeted tracer using a neopentyl glycol structureSuzuki, Hiroyuki, Kannaka, Kento, Mizuki Hirayama, Yamashita, Tomoki, Yuta Kaizuka, Kobayashi, Ryota, Yasuda, Takahiro, Takahashi, Kazuhiro, Uehara, Tomoya · 2024 · Figshare
- An Integrated Analysis of Four Targeted Thorium Conjugates to Assess the 227 Th and 223 Ra Distribution and Tissue-Related RadiationMichael Block, Adriaan Cleton, Carsten Zieschang, Sandra Johanssen, Thorsten Poethko, Hartwig Hennekes, Christoph Niederalt · 2025 · Cancer Biotherapy and Radiopharmaceuticals
- 68 Ga/ 211 At-Labeled Specific NPY1R Peptide-Based Molecular Probe for Glioma-Targeted Imaging and Alpha TherapyRong Gan, Duling Xu, Weihao Liu, Jiadi Liu, Yi Yang, Ning Liu, Qiyue Zhang, Zhimin Wang, Hongyan Li · 2026 · Biomacromolecules
- Anti-cancer and dual inhibitory potential of PI3K/AKT and Ras/MAPK/ERK signalling of a novel zinc (II) trinuclear complex with tetradentate schiff base ligand and azido ion in prostate adenocarcinoma: synthesis, in silico and in vitro evaluationAbdul Wasai, Adhiraj Roy, Mamata Barua, Pameli Ghosh, Anjali Saxena, Yassir Boulaamane, Nainee Goyal, Anshuman Chandra, Subratanath Koner, Sandip Saha et al. · 2026 · Journal of Molecular Structure
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- Performance Evaluation of Single- and Double-Layer CZT Compton Cameras for 225 Ac ImagingGyohyeok Song, Biswajit Das, Youngho Seo, Gyuseong Cho, J. Caravaca Rodríguez · 2026 · IEEE Transactions on Nuclear Science
- [225Ac]Ac–anti-DLL3 targeted alpha therapy for neuroendocrine tumors: preclinical radiosynthesis, biodistribution, and therapeutic efficacySyed Qaiser Shah, Ralph Santos‐Oliveira, Derya İlem‐Özdemir · 2026 · Journal of Radioanalytical and Nuclear Chemistry
- Highly Efficient Extraction of 212 Pb/ 212 Bi from the Decay Chain of 232 Th‐Based on Anion Exchange in Bromide MediumLifeng Chen, Wannian Feng, Yuezhou Wei, Xuexiang He, Shaoying Wang, Zhongyuan Zhou, Qian Wu, Ningchao Zheng, Xiangbiao Yin, X. H. Li et al. · 2026 · Advanced Science
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- Clinical research analysis of [225Ac]Ac-DOTATATE therapy for neuroendocrine neoplasmsHongyu Yang, Meiling Hu, Bingyan Shen, Ya Liu, Lin Liu, Yu Zhang, Yue Chen · 2026 · European Journal of Nuclear Medicine and Molecular Imaging
- Effect of dispersive and relativistic optical model potentials on the production cross-section calculation of 225Ac from 232Th using proton energyOlumide Oluwasanmi Ige, Tongshinen S. Longmena, Sunday Adesunloye Jonah · 2026 · Nuclear Energy and Technology
- PSMA-targeted radioligand therapy in advanced prostate cancer: a narrative review of ^177Lu-PSMA, emerging ^225Ac-PSMA strategies, and therapeutic sequencingNatalia Gierulska, Nina Jankowska, Adrianna Kwiatkowska, Piotr Kuchno, Kinga Łysak, Katarzyna Szklener, Kamil Kośmider, Magdalena Skórzewska · 2026 · Oncology Reviews
- Monte Carlo Simulation of Medical Isotopes Production by Irradiation of nat U and 232 Th Targets with P, α, 9 Be and 12 CQiuying Liang, Tiancheng Lai, Guanghui Yang, Qiong Yang, Fen Fu, Xunchao Zhang · 2026 · Nuclear Science and Engineering
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- The Second Nitrogen Fits: Development of Diazine-Based Macrocyclic Chelators to Stably Bind Radionuclides Used in Targeted Alpha TherapyMagdalena Blei, Lukas Waurick, Björn Drobot, Santiago Andrés Brühlmann, Charlotte Duchemin, Edgars Mamis, Muhammad Inzamam, Thierry Storà, Nadia Audouin, Thomas Sounalet et al. · 2026 · Inorganic Chemistry
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