The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.
Antimicrobial Resistance and the Alternative Resources with Special Emphasis on Plant-Based Antimicrobials—A Review
Open accessAbstract
Indiscriminate and irrational use of antibiotics has created an unprecedented challenge for human civilization due to microbe’s development of antimicrobial resistance. It is difficult to treat bacterial infection due to bacteria’s ability to develop resistance against antimicrobial agents. Antimicrobial agents are categorized according to their mechanism of action, i.e., interference with cell wall synthesis, DNA and RNA synthesis, lysis of the bacterial membrane, inhibition of protein synthesis, inhibition of metabolic pathways, etc. Bacteria may become resistant by antibiotic inactivation, target modification, efflux pump and plasmidic efflux. Currently, the clinically available treatment is not effective against the antibiotic resistance developed by some bacterial species. However, plant-based antimicrobials have immense potential to combat bacterial, fungal, protozoal and viral diseases without any known side effects. Such plant metabolites include quinines, alkaloids, lectins, polypeptides, flavones, flavonoids, flavonols, coumarin, terpenoids, essential oils and tannins. The present review focuses on antibiotic resistance, the resistance mechanism in bacteria against antibiotics and the role of plant-active secondary metabolites against microorganisms, which might be useful as an alternative and effective strategy to break the resistance among microbes.
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Cites
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Cited by
Antibacterial Activity of Some Flavonoids and Organic Acids Widely Distributed in Plants
Adamczak, A., Ożarowski, M., & Karpiński, T. M. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm9010109 · Cited by 478
Graphitic carbon nitride-based materials for photocatalytic antibacterial application
Kong, X., Liu, X., Zheng, Y., Chu, P. K., Zhang, Y., & Wu, S. (2021) · Materials Science and Engineering: R: Reports · doi:10.1016/j.mser.2021.100610 · Cited by 259
Phytochemicals and antimicrobial activity of coconut water (Cocos nucifera) on microbial pathogens
Anyiam, I. V., & Opara, C. N. (2023) · GSC Biological and Pharmaceutical Sciences · doi:10.30574/gscbps.2023.25.2.0476 · Cited by 8
Metadata
- Authors
- Chandra, H., Bishnoi, P., Yadav, A., Patni, B., Mishra, A., & Nautiyal, A.
- Venue
- Plants
- Publisher
- MDPI AG
- Published
- 2017-04-10
- Volume
- 6
- Issue
- 2
- Pages
- 16
- ISSN
- 2223-7747 (ISSN-L)
- OpenAlex
- W2606416324
- Cited by
- 389
- References
- 42
- FWCI
- 35.24
- Type
- journal article
- Language
- en
- Open access
- gold
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- Chandra, H., Bishnoi, P., Yadav, A., Patni, B., Mishra, A., & Nautiyal, A. (2017). Antimicrobial Resistance and the Alternative Resources with Special Emphasis on Plant-Based Antimicrobials—A Review. Plants. https://doi.org/10.3390/plants6020016
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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