A Mini-Review of Human Studies on Cholesterol-Lowering Properties of Probiotics
Open accessAbstract
Cardiovascular diseases (CVD) are the major health issue of modernized society with a high mortality rate. Lifestyle, genetic makeup, and diet are some of the major influencing factors associated with CVD. The dyslipidemia is one such factor related to the development of several CVD. Many studies proved that the consumption of probiotics confers several health benefits. Several studies reported the evaluation of the cholesterol-lowering ability of probiotics (probiotics that showed positive effect in vitro and in vivo studies) in human volunteers. The current review summarizes the outcomes of human studies on the cholesterol-lowering property of probiotics. Probiotic consumption significantly improved the health status of hypercholesteremic patients by reducing the low-density lipoprotein cholesterol, total cholesterol, triglyceride levels, and increased the high-density lipoprotein cholesterol. The probiotic supplementation improved the lipid profile of diabetic patients, and obese people as well. However, not all probiotic interventions are effective against dyslipidemia. The results are controversial and depend on several factors such as probiotic strain, dose, duration of the treatment, lifestyle changes, etc. This literature survey indorses additional studies on the cholesterol-lowering property of probiotics, which could help to reduce the risk of CVD and other dyslipidemia associated health issues.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Probiotics reduce blood cholesterol levels.
“In addition to modulating the immune system, the positive health effects of taking probiotics include: the improvement of lactose tolerance and digestion [199,205], the prevention and treatment of gastrointestinal infections [206], the prevention of colorectal cancer [203,207], reduction in blood cholesterol levels [208,209,210], and the improvement of mental health via the gut-brain axis [211].”
From Lactic Acid Bacteria in Raw-Milk Cheeses: From Starter Cultures to Probiotic Functions (2022) · cites this paper as [208]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
The citation lists haven’t been fetched yet
References 67 · Cited by 37
Research works printed but not linked: 1
- Food and Agriculture Organization of the United Nations; World Health Organization. Probiotics in food: Health and nutritional properties and guidelines for evaluation. FAO Food Nutr. Pap. 2006, 85, 1-50.
- Authors
- Sivamaruthi, B. S., Kesika, P., & Chaiyasut, C.
- Affiliations
- Chiang Mai University (TH)
- Corresponding author
- Sivamaruthi, Bhagavathi Sundaram
- Chaiyasut, Chaiyavat
- Venue
- Scientia Pharmaceutica
- Publisher
- MDPI AG
- Published
- 2019-10-14
- Volume
- 87
- Issue
- 4
- Pages
- 26
- ISSN
- 0036-8709 (ISSN-L)
- 2218-0532
- OpenAlex
- W2979621227
- Cited by
- 37
- References
- 67
- Citations by year
- 2026: 3 · 2025: 5 · 2024: 4 · 2023: 5 · 2022: 10 · 2021: 6 · 2020: 3 · 2019: 1
- FWCI
- 0.45
- Type
- journal article
- Language
- en
- Open access
- gold
- dx.doi.org
- Licence
- Locations
- Scientia Pharmaceutica (publishedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Chiang Mai University
- Commission on Higher Education
- Division of Chemistry
- Science and Technology Postgraduate Education and Research Development Office, Office of the Higher Education Commission
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Health Sciences › Medicine › Surgery › Lipoproteins and Cardiovascular Health
- Health Sciences › Medicine › Surgery › Natural Products and Biological Research
- Keywords
- probiotics, cholesterol-lowering effect, dyslipidemia, hypercholesterolemia, cardiovascular disease, lipid profile, LDL cholesterol, HDL cholesterol, triglycerides, diabetes mellitus, obesity, probiotic supplementation, probiotic strains
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
