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Knowledge and Attitudes Regarding Respiratory Syncytial Virus (RSV) Prevention: A Systematic Review
Abstract
Background: New strategies for respiratory syncytial virus (RSV) prevention are available and are in development, but their acceptance is crucial to their effectiveness. Objectives: This systematic review aims to summarize current quantitative and qualitative evidence regarding knowledge and attitudes relating to RSV prevention. Methods: Six databases (PubMed, Scopus, APA PsycArticles; APA PsycInfo; CINAHL Complete; Psychology and Behavioral Sciences Collection) and two preprint repositories (medRxiv and Preprints) were searched up until 23 December 2024 (PROSPERO: CRD42024602351). Results: Sixty-one articles were included, focusing on vaccination for the elderly and adults at risk (n = 10) or pregnant people (n = 24, of which 8 also examined preferences for maternal vs. infant immunization) and infant immunization (n = 27, of which 16 focused on palivizumab, with 6 focusing on adherence to its monthly administration). Eighteen articles assessed attitudes in healthcare professionals. Overall, findings showed limited knowledge and awareness of RSV but generally positive attitudes towards prevention strategies and moderate to high intentions and uptake rates. Protection against the disease and perceived severity promoted acceptance, whereas concerns about side effects hindered it. Maternal vaccination was more acceptable than infant immunization. Conclusions: Attitudes towards RSV prevention options were generally favorable. Should more options become available, preferences may depend on which options are available, their characteristics, and how they are framed and presented. These insights highlight the importance of education on RSV grounded in decision-making literature, while recognizing the likely favorable reception of preventive measures across target age-populations.
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Tucker, T., Garvey, Z., O'Sullivan, D., & Loza, A. (2024) · O&G Open · doi:10.1097/og9.0000000000000026 · Cited by 3
Kooiman, L. M. P., Kamps, A. W. A., Dassel, A. C. M., Brand, P. L. P., & Bekhof, J. (2018) · Acta Paediatrica · doi:10.1111/apa.14689 · Cited by 2
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Gavaruzzi, T., Caserotti, M., Bonaiuti, R., Bonanni, P., Crescioli, G., Tommaso, M. D., Lombardi, N., Lotto, L., Ravaldi, C., Rubaltelli, E., et al. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12103469 · Cited by 2
Self-citationBehavioural interventions to increase adherence to palivizumab prophylaxis in children with CHD
Erolu, E., Kıbrıs, Ö., Tosun, Y., Yıldırım, A., Pamukçu, Ö., Başar, E. Z., Babaoğlu, K., Epçaçan, S., Dönmez, Y. N., Giray, D., et al. (2024) · Cardiology in the Young · doi:10.1017/s1047951124024946 · Cited by 2
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The more the merrier? Two online experiments on how decoys can increase vaccine uptake.
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Research works printed but not linked: 4
- Walsh, E., Falsey, A., Patton, M., Stacey, H., Eiras, D.P., Jiang, Q., Woodside, J., Mikati, T., Kalinina, E., and Cooper, D. (2024, January 13–16). Efficacy of a Bivalent RSVpreF Vaccine in Older Adults Beyond a First RSV Season. Proceedings of the 8th ReSViNET Conference, Mumbai, India.
- Wilson, E., Goswami, J., Doreski, P.A., Marc, G.P., Jimenez, G., Priddy, F., Lin, N., Le Cam, N., Karen Slobod, K., and Stoszek, S.K. (2024, January 13–16). Efficacy and Safety of MRNA-1345, an RSV Vaccine, in Older Adults: Results through ≥6 Months of Follow-up and Evaluation of Correlate of Protection Against RSV. Proceedings of the 8th ReSViNET Conference, Mumbai, India.
- Sallam, M., Kherfan, T., Al-Farajat, A., Nemrawi, L., Atawneh, N., Fram, R., and Fram, K. (2024). Attitude to RSV Vaccination Among a Cohort of Pregnant Women in Jordan. Preprint. · DOI
- Alzahrani, 2023, Parental knowledge of RSV infection and attitude to infant immunization with monoclonal antibodies in western region, Saudi Arabia, AMJ, 16, 842
Metadata
- Authors
- Gavaruzzi, T., Ceccarelli, A., Nanni, C., Vignali, C., Colonnello, V., Caserotti, M., Riccò, M., & Gori, D.
- Venue
- Vaccines
- Publisher
- MDPI AG
- Published
- 2025-02-06
- Volume
- 13
- Issue
- 2
- Pages
- 159
- ISSN
- 2076-393X
- Cited by
- 29
- References
- 102
- Language
- en
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.