The DOI matches its Crossref record; 115 of the 115 references it cites were found in a registry or an index.
Techniques of assessing small airways dysfunction
Open accessAbstract
The small airways are defined as those less than 2 mm in diameter. They are a major site of pathology in many lung diseases, not least chronic obstructive pulmonary disease (COPD) and asthma. The small airways are frequently involved early in the course of these diseases, with significant pathology demonstrable often before the onset of symptoms or changes in spirometry and imaging. Despite their importance, they have proven relatively difficult to study. This is in part due to their relative inaccessibility to biopsy and their small size which makes their imaging difficult. Traditional lung function tests may only become abnormal once there is a significant burden of disease within them. This has led to the term 'the quiet zone' of the lung. In recent years, more specialised tests have been developed which may detect these changes earlier, perhaps offering the possibility of earlier diagnosis and intervention. These tests are now moving from the realms of clinical research laboratories into routine clinical practice and are increasingly useful in the diagnosis and monitoring of respiratory diseases. This article gives an overview of small airways physiology and some of the routine and more advanced tests of airway function.
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Interpretative strategies for lung function tests
Pellegrino, R., Viegi, G., Brusasco, V., Crapo, R. O., Burgos, F., Casaburi, R., Coates, A., van der Grinten, C. P. M., Gustafsson, P., Hankinson, J., et al. (2005) · European Respiratory Journal · doi:10.1183/09031936.05.00035205 · Cited by 5,945
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The Nature of Small-Airway Obstruction in Chronic Obstructive Pulmonary Disease
Hogg, J. C., Chu, F., Utokaparch, S., Woods, R., Elliott, W. M., Buzatu, L., Cherniack, R. M., Rogers, R. M., Sciurba, F. C., Coxson, H. O., et al. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa032158 · Cited by 3,782
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Small-Airway Obstruction and Emphysema in Chronic Obstructive Pulmonary Disease
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Site and Nature of Airway Obstruction in Chronic Obstructive Lung Disease
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The Relations between Structural Changes in Small Airways and Pulmonary-Function Tests
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The Pathology of Chronic Obstructive Pulmonary Disease
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Metadata
- Authors
- McNulty, W., & Usmani, O. S.
- Venue
- European Clinical Respiratory Journal
- Publisher
- Informa UK Limited
- Published
- 2014-01
- Volume
- 1
- Issue
- 1
- Pages
- 25898
- ISSN
- 2001-8525 (ISSN-L)
- OpenAlex
- W2030159044
- Cited by
- 275
- References
- 115
- FWCI
- 7.27
- Type
- journal article
- Language
- en
- Open access
- gold
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.