The DOI matches its Crossref record.
PENGARUH pH TERHADAP LAMANYA PENYIMPANAN SEDIAAN ESKTRAK DAUN SELIGI DAN EUGENOL DARI MINYAK DAUN CENGKEH SEBAGAI OBAT ANTINYERI
Open accessAbstract
Penyakit nyeri merupakan suatu perasaan yang tidak nyaman baik secara sensorik maupun emosional yang ditandai dengan kerusakan jaringan maupun tidak. Biasanya orang Indonesia menggunakan tanaman obat untuk mengatasi hal tersebut, beberapa tanaman obat yang bermanfaat banyak dan dapat mengatasi penyakit nyeri yaitu tanaman cengkeh dan daun seligi. Tanaman tersebut memiliki efek analgesik dan antiinflamasi sehingga dapat digunakan untuk mengatasi masalah nyeri. Pada penelitian ini disajikan suatu formulasi sediaan untuk mengatasi nyeri dengan menggunakan pengujian pH. Terdapat 3 metode dalam pembuatan sediaan ini, diantaranya yaitu pembuatan ekstrak daun seligi, pembuatan eugenol dari minyak daun cengkeh, dan formulasi sedian setelah itu akan dilakukan pengujian pH pada hari ke-1 dan ke-20. Yang masuk dalam SNI dan aman dipakai saat terkena kulit terdapat pada formulasi S6, dimana perbandingan eugenol lebih sedikit dibandingkan dengan ekstrak daun seligi.      Kata kunci : Analgesik, Eugenol, Nyeri, pH, Seligi.
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If the pH of the preparation is higher than the physiological pH, it can cause irritation and dry skin.
“If the pH of the preparation is higher than the physiological pH, it can cause irritation and dry skin [14].”
From Optimization of Carrageenan Concentration as an Emulsifier in Banana Peel Extract Body Lotion with Irritation Assessment (2025) · cites this paper as [14]
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Research works printed but not linked: 6
- Ansel, H.C., (2008), Pengantar Bentuk Sediaan Farmasi Edisi Keempat. Jakarta : UI Press
- Hastuti, S. Dan Safitri, I.A, (2015), Aktifitas Analgetik Ekstrak Etanol Daun Seligi (Phyllanthus buxifolius Muell. Arg.) terhadap Mencit Jantan Galur Balb/c. IJMS 2(1), pp. 11-15.
- Pratiwi, N., Jusadi, D., dan Nuryanti, S, (2016), Pemanfaatan Minyak Cengkeh Syzigium aromaticum untuk Meningkatkan Efisiensi Pakan pada Ikan Patin Pangasianodon hypophthalamus (Sauvage, 1876), Jurnal Iktiologi Indonesia 16(3), pp. 233-242.
- Safitri, I.A. dan Hastuti, S., (2014), Uji Daya Analgetik Ekstrak Etanol Daun Seligi Seligi (Phyllanthus buxifolius Muell. Arg.) terhadap Mencit Galur Swiss. IJMS 1(2), pp. 35-40.
- Syamsiah, N. Dan Endang Muslihat, (2015), Pengaruh Terapi Relaksasi Autogenik terhadap Tingkat Nyeri Akut pada Pasien Abdominal Pain di IGD RSUD Karawang 2014, Jurnal Ilmu Kepererawatan 3(1), pp. 1-7.
- Towaha, Juniaty, (2012), Manfaat Eugenol Cengkeh dalam Berbagi Industri di Indonesia. Jurnal Balai Penelitian Tanaman Industri dan Penyegar: Jawa Barat, pp.79-90.
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Meitasari, A. D., MH, M. F. Z., Kurnianingsih, R., Wigatiningtyas, A., & Juliyanti (2025) · Journal of Tropical Pharmacy and Chemistry · doi:10.30872/jtpc.v9i3.321 · Cited by 1
Metadata
- Authors
- Dewi, D. R. N., Zakkia, L. U., Khoiruddin, W., & Harismah, K.
- Affiliations
- Muhammadiyah University of Surakarta (ID)
- ORCID
- Harismah, Kun
- Venue
- Prosiding Sains Nasional dan Teknologi
- Published
- 2018-08-29
- Volume
- 1
- Issue
- 1
- ISSN
- 2964-5131 (ISSN-L)
- 2964-2531
- OpenAlex
- W3087300012
- Cited by
- 3
- References
- 0
- Citations by year
- 2024: 1 · 2023: 1 · 2022: 1
- FWCI
- 0.00
- Type
- journal article
- Language
- id
- Open access
- Locations
- Prosiding Sains Nasional dan Teknologi (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry Medicinal Plant Applications
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Drug Discovery › Pharmacology and Nanomedicine Research
- Keywords
- pH, storage stability, analgesic formulation, Syzygium aromaticum, clove leaf extract, eugenol, Symplocos paniculata, analgesia, anti-inflammatory agents, topical formulation
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