Antioxidants from microalgae and their potential impact on human well-being
Open accessAbstract
In recent times, there has been a revolutionary surge in antioxidant research, with a focus on harnessing microalgae to enhance wellness and extend human longevity. Microalgae, a diverse group of unicellular photosynthetic organisms, have emerged as promising sources of natural antioxidants due to their ability to synthesize various bioactive compounds, including carotenoids, polyphenols, and tocopherols. These antioxidants play a pivotal role in scavenging free radicals and reducing oxidative stress, known contributors to aging and chronic diseases. This review provides an over-view of recent advancements in understanding microalgae’s antioxidant potential, covering their biochemical composition, extraction techniques, and purification methods. Moreover, it delves into compelling in vitro and in vivo studies showcasing microalgae-derived antioxidants’ protective effects against oxidative damage, inflammation, cardiovascular diseases, and neurodegenerative disorders. The sustainable cultivation of microalgae in controlled environments further supports the potential for large-scale production and commercialization of their antioxidant compounds. As microalgae continue to revolutionize antioxidant research, they hold immense promise in developing novel preventive and therapeutic strategies to promote human health and wellbeing.
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Key microalgal antioxidants include carotenoids, phycobiliproteins, phenolic compounds, vitamins C and E, and omega-3 PUFAs like EPA and DHA.
“Key microalgal antioxidants include carotenoids (e.g., astaxanthin, β-carotene, and lutein); phycobiliproteins (e.g., phycocyanin); phenolic compounds; vitamins C and E; and omega-3 PUFAs like EPA and DHA [45].”
From Microalgae Bioactives for Functional Food Innovation and Health Promotion (2025) · cites this paper as [45]
The Introduction identifies the listed carotenoids, phycocyanin, phenolic compounds, and vitamin E as microalgal antioxidants; its antioxidant-production table also lists ascorbic acid (vitamin C). It discusses omega-3 fatty acids as microalgae-derived antioxidants, but the passages retrieved for EPA and DHA do not identify those specific fatty acids, so that part of the list is not verified. (LLM, conf=0.86)
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References 139 · Cited by 48
- Authors
- Pereira, L., Cotas, J., & Valado, A.
- Affiliations
- University of Coimbra (PT)
- Universidade Politécnica de Coimbra (PT)
- Corresponding author
- Pereira, Leonel
- Venue
- Exploration of Drug Science
- Publisher
- Open Exploration Publishing
- Published
- 2024-05-31
- Pages
- 292-321
- ISSN
- 2836-7677 (ISSN-L)
- OpenAlex
- W4399240723
- Cited by
- 48
- References
- 139
- Citations by year
- 2026: 20 · 2025: 24 · 2024: 4
- FWCI
- 15.38
- Type
- journal article
- Language
- en
- Update notices
- correction (2024-12-03)
- Open access
- diamond
- doi.org
- Locations
- Exploration of Drug Science (publishedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
- Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
- Keywords
- microalgae, antioxidants, carotenoids, polyphenols, tocopherols, oxidative stress, free radical scavenging, aging, chronic disease, inflammation, cardiovascular disease, neurodegenerative diseases, antioxidant extraction, microalgae cultivation, human health
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